基因敲除/敲入小鼠模型的建立和标准化
81372491
2013
H1826.肿瘤学研究新技术与新方法
尹玉新
面上项目
教授
北京大学
185万元
基因敲除;C25_其它肿瘤;标准化;敲入;小鼠模型
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates T(H)17 differentiation | 期刊论文 | Lu Dan;Liu Liang;Ji Xin;Gao Yanan;Chen Xi;Liu Yu;Liu Yang;Zhao Xuyang;Li Yan;Lil Yunqiao;Jin Yan;Zhang Yu;McNutt Michael A.;Yin Yuxin |
| 2 | Workflow development for targeted lipidomic quantification using parallel reaction monitoring on a quadrupole-time of flight mass spectrometry | 期刊论文 | Zhou Juntuo;Liu Chunlei;Si Dandan;Jia Bing;Zhong Lijun;Yin Yuxin |
| 3 | New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds | 期刊论文 | Zhang Yu;Liu Bin;Wu Xingyu;Li Ridong;Ning Xianling;Liu Yu;Liu Zhenming;Ge Zemei;Li Runtao;Yin Yuxin |
| 4 | Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation | 期刊论文 | Wang Yufei;Wu Xingyu;Du Mufeng;Chen Xi;Ning Xianling;Chen Hong;Wang Siyuan;Liu Jia;Liu Zhenming;Li Ridong;Fu Ge;Wang Chunguang;McNutt Michael A.;Zhou Demin;Yin Yuxin |
| 5 | Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase m2 isoform. | 期刊论文 | Ning Xianling;Qi Hailong;Li Ridong;Jin Yan;McNutt Michael A.;Yin Yuxin |
| 6 | PTEN alpha Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning | 期刊论文 | Wang Pan;Mei Fan;Hu Jiapan;Zhu Minglu;Qi Hailong;Chen Xi;Li Ruiqi;McNutt Michael A.;Yin Yuxin |
| 7 | 抗癌基因PTEN在维持基因组稳定性中的作用及其机理研究 | 奖励 | 尹玉新;梁会;王光熙;冯嘉汶;何世明;李扬;孙卓;陈铸鸿;朱明璐;张重;梁婧 |
| 8 | An HPLC-MS/MS method for quantitation of Gly-MCA in mouse plasma: Application to a pharmacokinetic study | 期刊论文 | Liu Jia;Lian Guan;Wang Ting;Ma Yuanheng;Zhou Junto;Jiang Changtao;Yin Yuxin |
| 9 | Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression | 期刊论文 | Liu Yang;Zhang Zhong;Liang Hui;Zhao Xuyang;Liang Ling;Wang Guangxi;Yang Jingyi;Jin Yan;McNutt Michael A.;Yin Yuxin |
| 10 | PTEN regulates RPA1 and protects DNA replication forks | 期刊论文 | Wang Guangxi;Li Yang;Wang Pan;Liang Hui;Cui Ming;Zhu Minglu;Guo Limei;Su Qian;Sun Yujie;McNutt Michael A.;Yin Yuxin |
| 11 | USP9X destabilizes pVHL and promotes cell proliferation | 期刊论文 | Zhang Cong;Peng Zuohan;Zhu Minglu;Wang Penglong;Du Xiao;Li Xiang;Liu Yu;Jin Yan;McNutt Michael A.;Yin Yuxin |
| 12 | PTEN beta is an alternatively translated isoform of PTEN that regulates rDNA transcription | 期刊论文 | Liang Hui;Chen Xi;Yin Qi;Ruan Danhui;Zhao Xuyang;Zhang Cong;McNutt Michael A.;Yin Yuxin |
| 13 | PTEN Controls the DNA Replication Process through MCM2 in Response to Replicative Stress | 期刊论文 | Feng Jiawen;Liang Jing;Li Jiaju;Li Yunqiao;Liang Hui;Zhao Xuyang;McNutt Michael A.;Yin Yuxin |
| 14 | Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry | 期刊论文 | Zhou Juntuo;Yin Yuxin |
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