LncRNA GLS-AS介导m6A去甲基化在酸性微环境诱导胰腺癌代谢重编程中作用及机制
81872030
2018
H1805.肿瘤表观遗传
赵刚
面上项目
教授
华中科技大学
57万元
酸性微环境;胰腺癌;m6A去甲基化;谷氨酰胺酶;代谢重编程
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | LncRNA HIF1A-AS1 Promotes Gemcitabine Resistance of Pancreatic Cancer by Enhancing Glycolysis through Modulating the AKT/YB1/HIF1α Pathway. | 期刊论文 | Xu Fengyu;Huang Mengqi;Chen Qingyong;Niu Yi;Hu Yuhang;Hu Ping;Chen Ding;He Chi;Huang Kang;Zeng Zhu;Tang Jiang;Wang Fan;Zhao Yong;Wang Chunyou;Zhao Gang |
| 2 | Hypoxic exosomal HIF-1 alpha-stabilizing circZNF91 promotes chemoresistance of normoxic pancreatic cancer cells via enhancing glycolysis | 期刊论文 | Zeng Zhu;Zhao Yong;Chen QingYong;Zhu Shuai;Niu Yi;Ye Zeng;Hu Ping;Chen Ding;Xu Peng;Chen Jinghuang;Hu Chaojie;Hu Yuhang;Xu Fengyu;Tang Jiang;Wang Fan;Han Shengbo;Huang Mengqi;Wang Chunyou;Zhao Gang |
| 3 | LncRNA ZNFTR functions as an inhibitor in pancreatic cancer by modulating ATF3/ZNF24/VEGFA pathway | 期刊论文 | Li Wei;Han Shengbo;Hu Ping;Chen Ding;Zeng Zhu;Hu Yuhang;Xu Fengyu;Tang Jiang;Wang Fan;Zhao Yong;Huang Mengqi;Zhao Gang |
| 4 | Nutrient Stress-Dysregulated Antisense lncRNA GLS-AS Impairs GLS-Mediated Metabolism and Represses Pancreatic Cancer Progression. | 期刊论文 | Deng Shi Jiang;Chen Heng Yu;Zeng Zhu;Deng Shichang;Zhu Shuai;Ye Zeng;He Chi;Liu Ming Liang;Huang Kang;Zhong Jian Xin;Xu Feng Yu;Li Qiang;Liu Yang;Wang Chunyou;Zhao Gang |
| 5 | Hypoxia-induced feedback of HIF-1 alpha and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein | 期刊论文 | Liu Mingliang;Zhong Jianxin;Zeng Zhu;Huang Kang;Ye Zeng;Deng Shijiang;Chen Hengyu;Xu Fengyu;Li Qiang;Zhao Gang |
| 6 | A reciprocal feedback between N6-methyladenosine reader YTHDF3 and lncRNA DICER1-AS1 promotes glycolysis of pancreatic cancer through inhibiting maturation of miR-5586-5p. | 期刊论文 | Hu Yuhang;Tang Jiang;Xu Fengyu;Chen Jinhuang;Zeng Zhu;Han Shengbo;Wang Fan;Wang Decai;Huang Mengqi;Zhao Yong;Huang Yan;Zhuo Wenfeng;Zhao Gang |
| 7 | A reciprocal feedback of Myc and lncRNA MTSS1-AS contributes to extracellular acidity-promoted metastasis of pancreatic cancer | 期刊论文 | Hu Yuhang;Wang Fan;Xu Fengyu;Fang Kaifeng;Fang Zhi;Shuai Xiaoming;Cai Kailin;Chen Jinhuang;Hu Ping;Chen Ding;Xu Peng;Hu Chaojie;Zeng Zhu;Zhong Jianxin;Li Wei;Tang Jiang;Huang Mengqi;Zhao Yong;Wang Chunyou;Zhao Gang |
| 8 | LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1 alpha | 期刊论文 | Zeng Zhu;Xu Feng yu;Zheng Hai;Cheng Ping;Chen Qing yong;Ye Zeng;Zhong Jian xin;Deng Shi jiang;Liu Ming liang;Huang Kang;Li Qiang;Li Wei;Hu Yu hang;Wang Fan;Wang Chun you;Zhao Gang |
| 9 | A reciprocal feedback between colon cancer cells and Schwann cells promotes the proliferation and metastasis of colon cancer | 期刊论文 | Shengbo Han;Decai Wang;Yan Huang;Zhu Zeng;Peng Xu;Hewei Xiong;Zunxiang Ke;Ya Zhang;Yuhang Hu;Fan Wang;Jie Wang;Yong Zhao;Wenfeng Zhuo;Gang Zhao |
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