长链非编码RNA 9130221H12Rik调控GSK-3α在衰老小鼠模式分离功能障碍中的作用及机理研究

81871108
2018
H1901.衰老机制与调控
刘丹
面上项目
教授
华中科技大学
56万元
脑老化;长链非编码RNA;糖原合酶激酶3α;模式分离;记忆
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Social isolation reinforces aging-related behavioral inflexibility by promoting neuronal necroptosis in basolateral amygdala 期刊论文 Juan Zhang;Dan Liu
2 Targeting miR‐124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model 期刊论文 Wen‐Dai Bao;Xiao‐Ting Zhou;Lan‐Ting Zhou;Fudi Wang;Xiaoping Yin;Youming Lu;Ling‐Qiang Zhu;Dan Liu
3 Targeting the Neuronal Activity of Prefrontal Cortex: New Directions for the Therapy of Depression. 期刊论文 Zhou Xiaoting;Bao Wendai;Liu Dan;Zhu Lingqiang
4 The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases 期刊论文 Moxin Wu;Manqing Zhang;Xiaoping Yin;Kai Chen;Zhijian Hu;Qin Zhou;Xianming Cao;Zhiying Chen;Dan Liu
5 miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer’s disease 期刊论文 Kai Zheng;Fan Hu;Yang Zhou;Juan Zhang;Jie Zheng;Chuan Lai;Wan Xiong;Ke Cui;Ya-Zhuo Hu;Zhi-Tao Han;Hong-Hong Zhang;Jian-Guo Chen;Heng-Ye Man;Dan Liu;Youming Lu;Ling-Qiang Zhu
6 Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway. 期刊论文 Xie AJ;Hou TY;Huang HZ;Zheng J;Li K;Man HY;Hu YZ;Han ZT;Zhang HH;Wei N;Wang JZ;Liu D;Lu Y;Zhu LQ
7 Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease. 期刊论文 Tong-Yao Hou;Yang Zhou;Ling-Shuang Zhu;Xiong Wang;Pei Pang;Ding-Qi Wang;Zhen-Yu Liuyang;Hengye Man;Youming Lu;Ling-Qiang Zhu;Dan Liu
8 A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb 期刊论文 Mei Ma;Wan Xiong;Fan Hu;Man-Fei Deng;Xian Huang;Jian-Guo Chen;Heng-Ye Man;Youming Lu;Dan Liu;Ling-Qiang Zhu
9 Ferroptosis, a Potential Therapeutic Target in Alzheimer’s Disease 期刊论文 Kai Chen
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