金属配合物导致基因组化学修饰的测序技术开发和分布规律解析

91953201
2019
B0702.生物分子的化学生物学
伊成器
重大研究计划
教授
北京大学
300万元
测序技术;分布规律;核酸修饰;顺铂;金属配合物
2020-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Multispecific Platinum(IV) Complex Deters Breast Cancer via Interposing Inflammation and Immunosuppression as an Inhibitor of COX‐2 and PD‐L1 期刊论文 Suxing Jin;Nafees Muhammad;Yuewen Sun;Yehong Tan;Hao Yuan;Dongfan Song;Zijian Guo;Xiaoyong Wang
2 The induction of PANoptosis in KRAS-mutant pancreatic ductal adenocarcinoma cells by a multispecific platinum complex 期刊论文 Xin Yuan;Shuren Zhang;Xuanmeng Zhong;Hao Yuan;Dongfan Song;Xiaoyu Wang;Hanyang Yu;Zijian Guo
3 Platinum(IV) Complexes as Inhibitors of STAT3 and Regulators of the Tumor Microenvironment To Control Breast Cancer 期刊论文 Linxiang Cai;Ying Wang;Hanhua Chen;Yehong Tan;Tao Yang;Shuren Zhang;Zijian Guo;Xiaoyong Wang
4 Regulating tumor glycometabolism and the immune microenvironment by inhibiting lactate dehydrogenase with platinum(iv) complexes 期刊论文 Suxing Jin;Enmao Yin;Chenyao Feng;Yuewen Sun;Tao Yang;Hao Yuan;Zijian Guo;Xiaoyong Wang
5 Overcoming Cancer Resistance to Platinum Drugs by Inhibiting Cholesterol Metabolism 期刊论文 Ying Wang;Linxiang Cai;Hui Li;Hanhua Chen;Tao Yang;Yehong Tan;Zijian Guo;Xiaoyong Wang
6 Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells 期刊论文 Wenhao Yu;Xinlu Zhao;Abubakar S. Jalloh;Yachao Li;Yingying Zhao;Brandon Dinner;Yang Yang;Shian Ouyang;Tian Tian;Zihan Zhao;Rong Yang;Mingkuan Chen;Gregoire Lauvau;Zijian Guo;Peng Wu;Jie P. Li
7 Interfering in apoptosis and DNA repair of cancer cells to conquer cisplatin resistance by platinum(iv) prodrugs 期刊论文 Shuren Zhang;Xuanmeng Zhong;Hao Yuan;Yan Guo;Dongfan Song;Fen Qi;Zhenzhu Zhu;Xiaoyong Wang;Zijian Guo
8 Platinum‐Based TREM2 Inhibitor Suppresses Tumors by Remodeling the Immunosuppressive Microenvironment 期刊论文 Tao Yang;Shuren Zhang;Hao Yuan;Ying Wang;Linxiang Cai;Hanhua Chen;Xiaoyu Wang;Dongfan Song;Xiaohui Wang;Zijian Guo;Xiaoyong Wang
9 Manganese(ii) complexes stimulate antitumor immunity via aggravating DNA damage and activating the cGAS-STING pathway 期刊论文 Linxiang Cai;Ying Wang;Yayu Chen;Hanhua Chen;Tao Yang;Shuren Zhang;Zijian Guo;Xiaoyong Wang
10 BODIPY-Based Multifunctional Nanoparticles for Dual Mode Imaging-Guided Tumor Photothermal and Photodynamic Therapy 期刊论文 Zhongyan Chen;Yuncong Chen;Yunjian Xu;Xiangchao Shi;Zhong Han;Yang Bai;Hongbao Fang;Weijiang He;Zijian Guo
11 An AIE-based monofunctional Pt(ii) complex for photodynamic therapy through synergism of necroptosis–ferroptosis 期刊论文 Xiaoxue Zheng;Minglun Liu;Yanping Wu;Yuncong Chen;Weijiang He;Zijian Guo
12 Platinum-Based Two-Photon Photosensitizer Responsive to NIR Light in Tumor Hypoxia Microenvironment 期刊论文 Yanjun Wang;Xiangchao Shi;Hongbao Fang;Zhong Han;Hao Yuan;Zhenzhu Zhu;Lei Dong;Zijian Guo;Xiaoyong Wang
13 Characterizing off-target effects of genome editors 期刊论文 Xichen Rao;Huanan Zhao;Chuyun Shao;Chengqi Yi
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