DAPK1-mTORC1-Myc通路对T细胞糖酵解及其免疫功能的调控机制研究
81671539
2016
H1101.免疫系统发育与分化异常
杨想平
面上项目
教授
华中科技大学
60万元
T细胞代谢与功能;mTORC1;T细胞活化;自身免疫与抗肿瘤免疫;Myc
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | ATP6V0d2 mediates leucine-induced mTORC1 activation and polarization of macrophages | 期刊论文 | Li Pingfei;Deng Xiaofei;Luo Jing;Chen Yufei;Bi Guoyu;Gong Feili;Wei Zhengping;Liu Na;Li Huabin;Laurence Arian;Yang Xiang Ping |
| 2 | Regulation of T cell differentiation and function by epigenetic modification enzymes | 期刊论文 | Liu Huicheng;Li Pingfei;Wei Zhengping;Zhang Cai;Xia Minghui;Du Qiuyang;Chen Yufei;Liu Na;Li Huabin;Yang Xiang Ping |
| 3 | The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion | 期刊论文 | Xia Yu;Liu Na;Xie Xiuxiu;Bi Guoyu;Ba Hongping;Li Lin;Zhang Jinxia;Deng Xiaofei;Yao Yao;Tang Zhaohui;Yin Binjiao;Wang Jing;Jiang Kan;Li Zhuoya;Choi Yongwon;Gong Feili;Cheng Xiang;O'Shea John J;Chae Jae Jin;Laurence Arian;Yang Xiang Ping |
| 4 | DAPK1 (death associated protein kinase 1) mediates mTORC1 activation and antiviral activities in CD8( ) T cells. | 期刊论文 | Wei Zhengping;Li Pingfei;He Ran;Liu Huicheng;Liu Na;Xia Yu;Bi Guoyu;Du Qiuyang;Xia Minghui;Pei Lei;Wang Jing;Wang Guihua;Tang Zhao-Hui;Cheng Xiang;Li Huabin;Li Zhuoya;Ye Lilin;Laurence Arian;Lu Youming;Yang Xiang-Ping |
| 5 | Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2 alpha-mediated tumor progression | 期刊论文 | Liu Na;Luo Jing;Kuang Dong;Xu Sanpeng;Duan Yaqi;Xia Yu;Wei Zhengping;Xie Xiuxiu;Yin Bingjiao;Chen Fang;Luo Shunqun;Liu Huicheng;Wang Jing;Jiang Kan;Gong Feili;Tang Zhao hui;Cheng Xiang;Li Huabin;Li Zhuoya;Laurence Arian;Wang Guoping;Yang Xiang Ping |
| 6 | TFEB Mediates Immune Evasion and Resistance to mTOR Inhibition of Renal Cell Carcinoma via Induction of PD-L1 | 期刊论文 | Zhang Cai;Duan Yaqi;Xia Minghui;Dong Yuting;Chen Yufei;Zheng Lu;Chai Shuaishuai;Zhang Qian;Wei Zhengping;Liu Na;Wang Jing;Sun Chaoyang;Tang Zhaohui;Cheng Xiang;Wu Jie;Wang Guoping;Zheng Fang;Laurence Arian;Li Bing;Yang Xiang-Ping |
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