基于高通量CRISPR基因敲除筛选技术探讨肿瘤化疗耐药机制及对抗策略
31871344
2018
C0607.基因组学
费腾
面上项目
教授
东北大学
59万元
基因敲除;化疗耐药;基因编辑;全基因组筛选;人
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | An in silico drug repositioning workflow for host-based antivirals. | 期刊论文 | Li Zexu;Yao Yingjia;Cheng Xiaolong;Li Wei;Fei Teng |
| 2 | Deciphering essential cistromes using genome-wide CRISPR screens. | 期刊论文 | Fei Teng;Li Wei;Peng Jingyu;Xiao Tengfei;Chen Chen-Hao;Wu Alexander;Huang Jialiang;Zang Chongzhi;Liu X Shirley;Brown Myles |
| 3 | A chemical-enhanced system for CRISPR-Based nucleic acid detection. | 期刊论文 | Li Zihan;Zhao Wenchang;Ma Shixin;Li Zexu;Yao Yingjia;Fei Teng |
| 4 | A computational framework of host-based drug repositioning for broad-spectrum antivirals against RNA viruses. | 期刊论文 | Li Zexu;Yao Yingjia;Cheng Xiaolong;Chen Qing;Zhao Wenchang;Ma Shixin;Li Zihan;Zhou Hu;Li Wei;Fei Teng |
| 5 | Modeling CRISPR-Cas13d on-target and off-target effects using machine learning approaches | 期刊论文 | Cheng Xiaolong;Li Zexu;Shan Ruocheng;Li Zihan;Wang Shengnan;Zhao Wenchang;Zhang Han;Chao Lumen;Peng Jian;Fei Teng;Li Wei |
| 6 | Improving Cancer Immunotherapy with CRISPR-Based Technology. | 期刊论文 | Li Zexu;Fei Teng |
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