重型肝炎mfgl2分子在肝脏Kupffer 细胞M1/M2极化和NK细胞活化中的调节作用及其机制

81571989
2015
H2103.肝炎病毒与感染
宁琴
面上项目
教授
华中科技大学
60万元
巨噬细胞;重型乙型肝炎;肝损伤;纤维介素;自然杀伤细胞
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 乙型肝炎病毒感染合并酒精性脂肪肝小鼠模型的构建方法 专利 宁琴;罗小平;王洪武;吴婷;王晓晶;习东;陈培哲;黄丽华
2 Functional restoration of CD56bright NK cells facilitates immune control via IL-15 and NKG2D in patients under antiviral treatment for chronic hepatitis B 期刊论文 Tao Chen;Lin Zhu;Aichao Shi;Lin Ding;Xiaoping Zhang;Zhenmin Tan;Wei Guo;Weiming Yan;Meifang Han;Jidong Jia;Xiaoping Luo;Detlef Schuppan;Qin Ning
3 抗纤维介素蛋白的单克隆抗体及应用 专利 宁琴;罗小平;习东;王鸣;孙颖;王发席;严伟明
4 IL-33 protects Murine Viral Fulminant Hepatitis by targeting coagulation hallmark protein FGL2/fibroleukin expression 期刊论文 Haijing Yu;Yang Liu;Jiaquan Huang;Hongwu Wang;Weiming Yan;Dong Xi;Guanxin Shen;Xiaoping Luo;Qin Ning
5 湖北省科学技术奖励(自然科学奖)一等奖 奖励 宁琴;吴玉章;罗小平;韩梅芳;严伟明
6 Interference with KCTD9 inhibits NK cell activation and ameliorates fulminant liver failure in mice 期刊论文 Xiaoping Zhang;Lin Zhu;Yaoyong Zhou;Aichao Shi;Hongwu Wang;Meifang Han;Xiaoyang Wan;Semvua Bukheti Kilonzo;Xiaoping Luo;Tao Chen;Qin Ning
7 Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector Function 期刊论文 Xiaoping Zhang;Peng Wang;Tao Chen;Weiming Yan;Xiaoxu Guan;Guanxin Shen;Xiaoping Luo;Xiaoyang Wan;Qin Ning
8 Intrahepatic recruitment of cytotoxic NK cells contributes to autoimmune hepatitis progression. 期刊论文 Fang Xiao;Guo Ai;Weiming Yan;Xiaoyang Wan;Xiaoping Luo;Qin Ning
9 CD56bright natural killer cells induce HBsAg reduction via cytolysis and cccDNA decay in long-term entecavir-treated patients switching to peginterferon alfa-2a. 期刊论文 A. Shi;X. Zhang;F. Xiao;L. Zhu;W. Yan;M. Han;X. Luo;T. Chen;Q. Ning
10 Soluble Fgl2 restricts autoimmune hepatitis progression via suppressing Tc17 and conventional CD8+ T cell function 期刊论文 Ai G;Yan W;Yu H;Xiao F;Xi D;Ma K;Huang J;Luo X;Wan X;Ning Q
11 Non-alcoholic hepatic steatosis attenuates hepatitis B virus replication in an HBV-immunocompetent mouse model. 期刊论文 Danqing Hu;Hongwu Wang;Hai Wang;Yaqi Wang;Xiaoyang Wan;Weiming Yan;Xiaoping Luo;Qin Ning
12 Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis 期刊论文 Qun-Qun Jiang;Mei-fang Han;Ke Ma;Guang Chen;Xiao-Yang Wan;Semvua Bukheti Kilonzo;Wen-Yu Wu;Yong-Li Wang;Jie You;Qin Ning
13 Intracellular hepatitis B virus increases hepatic cholesterol deposition in alcoholic fatty liver via hepatitis B core protein 期刊论文 YaQi Wang;Ting Wu;DanQing Hu;XinXin Weng;PeiJer Chen;XiaoPing Luo;Hongwu Wang;Qin Ning
14 Clara Cell 10 kDa Protein Alleviates Murine Hepatitis virus strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-like protein 2 Expression 期刊论文 Haijing Yu;Yang Liu;Hongwu Wang;Xiaoyang Wan;Jiaquan Huang;Weiming Yan;Dong Xi;Xiaoping Luo;Guanxin Shen;Qin Ning
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