代谢综合征高游离脂肪酸血症促血管硬化的作用和机制研究
81570405
2015
H0214.动脉粥样硬化与动脉硬化
黄恺
面上项目
教授
华中科技大学
60万元
代谢综合征;1型多聚ADP核糖合成酶;高游离脂肪酸血症;血管硬化
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The role of CD27-CD70 signaling in myocardial infarction and cardiac remodeling. | 期刊论文 | Li Wei;Zhang Fengxiao;Ju Chenhui;Lv Suying;Huang Kai |
| 2 | Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy | 期刊论文 | Tan Xin;Hu Lizhi;Shu Zhiping;Chen Long;Li Xiangrao;Du Meng;Sun Dan;Mao Xiaoxiang;Deng Shan;Huang Kai;Zhang Fengxiao |
| 3 | The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation. | 期刊论文 | Du Meng;Yuan Lin;Tan Xin;Huang Dandan;Wang Xiaojing;Zheng Zhe;Mao Xiaoxiang;Li Xiangrao;Yang Liu;Huang Kun;Zhang Fengxiao;Wang Yan;Luo Xi;Huang Dan;Huang Kai |
| 4 | Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-kappaB Signaling Pathway. | 期刊论文 | Zhao Shengnan;Liang Minglu;Wang Yilong;Hu Ji;Zhong Yi;Li Jia;Huang Kai;Li Yiqing |
| 5 | PRMT4 overexpression aggravates cardiac remodeling following myocardial infarction by promoting cardiomyocyte apoptosis. | 期刊论文 | Yilong Wang;Chenhui Ju;Ji Hu;Kai Huang;Ling Yang |
| 6 | Absence of Interferon Regulatory Factor 1 Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice | 期刊论文 | Du Meng;Wang Xiaojing;Mao Xiaoxiang;Yang Liu;Huang Kun;Zhang Fengxiao;Wang Yan;Luo Xi;Wang Cheng;Peng Jiangtong;Liang Minglu;Huang Dan;Huang Kai |
| 7 | Role of adipokine zinc-α2-glycoprotein in coronary heart disease. | 期刊论文 | Dandan Huang;Xiaoxiang Mao;Jiangtong Peng;Min Cheng;Tao Bai;Meng Du;Kun Huang;Bing Liu;Liu Yang;Kai Huang;Fengxiao Zhang |
| 8 | PARP1-mediated PPARalpha poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease. | 期刊论文 | Huang Kun;Du Meng;Tan Xin;Yang Ling;Li Xiangrao;Jiang Yuhan;Wang Cheng;Zhang Fengxiao;Zhu Feng;Cheng Min;Yang Qinglin;Yu Liqing;Wang Lin;Huang Dan;Huang Kai |
| 9 | T0901317作为PARP1抑制剂的应用 | 专利 | 黄恺;张冯筱;黄丹 |
| 10 | GW3965作为PARP1抑制剂的应用 | 专利 | 黄恺;张冯筱;罗希 |
| 11 | 22(R)-羟基胆固醇作为PARP1抑制剂的应用 | 专利 | 黄恺;张冯筱;黄丹 |
| 12 | Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity. | 期刊论文 | Wang Cheng;Xu Wenjing;Zhang Yanqing;Huang Dan;Huang Kai |
| 13 | Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice | 期刊论文 | Ju Chenhui;Liu Chang;Yan Shu;Wang Yilong;Mao Xiaoxiang;Liang Minglu;Huang Kai |
| 14 | PARP1 promote autophagy in cardiomyocytes via modulating FoxO3a transcription. | 期刊论文 | Wang Cheng;Xu Wenjing;Zhang Yanqing;Zhang Fengxiao;Huang Kai |
| 15 | 代谢异常及相关心血管疾病的发病机制及治疗新策略 | 奖励 | 黄恺;张铭湘;陈璐璐;杨玲;付琴;李大主;程敏;黄丹;徐可树;张冯筱;杜萌;王成;秦伟栋;梁明露;彭江通 |
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