α2AR-AMPKα信号通路介导损伤线粒体原位复能预防痛觉中枢敏化的机制研究

81870883
2018
H0903.感觉障碍、疼痛与镇痛
崔剑
面上项目
副教授
中国人民解放军第三军医大学
56万元
胶质细胞;中枢敏化;神经病理性疼痛;线粒体动力学;躯体感觉神经元
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CXCR4/CX43 Regulate Diabetic Neuropathic Pain via Intercellular Interactions between Activated Neurons and Dysfunctional Astrocytes during Late Phase of Diabetes in Rats and the Effects of Antioxidant N-Acetyl-L-Cysteine 期刊论文 Dan Zhu;Tingting Fan;Yaohua Chen;Xingyue Huo;Yuping Li;Danyong Liu;Yin Cai;Chi Wai Cheung;Jing Tang;Jian Cui;Zhenyuan Xia
2 The Efficacy of an Ultrasound-Guided Improved Puncture Path Technique of Nerve Block/Pulsed Radiofrequency for Pudendal Neuralgia: A Retrospective Study 期刊论文 Dan Zhu;Zhenzhen Fan;Fujun Cheng;Yuping Li;Xingyue Huo;Jian Cui
3 Perisciatic Nerve Dexmedetomidine Alleviates Spinal Oxidative Stress and Improves Peripheral Mitochondrial Dynamic Equilibrium in a Neuropathic Pain Mouse Model in an AMPK-Dependent Manner 期刊论文 Yang Mu;Yang Mei;Yaohua Chen;Yuping Li;Dan Zhu;Jian Cui;Lehua Yu
4 Genetic Polymorphisms of PRKAA1(AMPKα1) and Postherpetic Pain Susceptibility: Multicenter, Randomized Control, Haplotype Analysis Study 期刊论文 Mei Yang;Qi Chen;Yu-Ping Li;Yao-hua Chen;Juan Xia;Jie Zeng;Le-hua Yu;Wei Li;Jian Cui
5 Effect of AMPK Subunit Alpha 2 Polymorphisms on Postherpetic Pain Susceptibility in Southwestern Han Chinese 期刊论文 Yang Mei;Yang Mu;Bo-Tao Tan;Yao-Hua Chen;Yu-Ping Li;Dan Zhu;Wei Li;Jian Cui;Le-Hua Yu
6 Propofol downregulates the activity of glutamatergic neurons in the basal forebrain via affecting intrinsic membrane properties and postsynaptic GABAARs 期刊论文 Yuping Li;Lin Chen;Dan Zhu;Yaohua Chen;Wanxiang Qin;Jian Cui
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