白血病干细胞免疫逃逸及其机制研究
81930004
2019
H08.血液系统
黄晓军
重点项目
教授
北京大学
297万元
异基因造血干细胞移植;白血病干细胞;微小残留病;免疫逃逸;急性白血病
2020-01-01到2024-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Glucocorticoid and glycolysis inhibitors cooperatively abrogate acute graft-versus-host disease | 期刊论文 | Qi Wen;Zheng-Li Xu;Yu Wang;Meng Lv;Yang Song;Zhong-Shi Lyv;Tong Xing;Lan-Ping Xu;Xiao-Hui Zhang;Xiao-Jun Huang;Yuan Kong |
| 2 | Optimizing outcomes for haploidentical hematopoietic stem cell transplantation in severe aplastic anemia with intensive GVHD prophylaxis: a review of current findings | 期刊论文 | Zheng-Li Xu;Xiao-Jun Huang |
| 3 | Targeting IFN-gamma-inducible lysosomal thiol reductase overcomes chemoresistance in AML through regulating the ROS-mediated mitochondrial damage | 期刊论文 | Niu Li-Ting;Wang Yu-Qing;Wong Catherine C. L.;Gao Shuai-Xin;Mo Xiao-Dong;Huang Xiao-Jun |
| 4 | Meta-Analysis of Interleukin-2 Receptor Antagonists as the Treatment for Steroid-Refractory Acute Graft-Versus-Host Disease | 期刊论文 | Meng-Zhu Shen;Jing-Xia Li;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Kai-Yan Liu;Xiao-Jun Huang;Shen-Da Hong;Xiao-Dong Mo |
| 5 | S1PR1作为白血病干细胞分子标志物的应用 | 专利 | 黄晓军;王语晴;任悦 |
| 6 | Monocyte subsets in bone marrow grafts may contribute to a low incidence of acute graft-vs-host disease for young donors | 期刊论文 | Qi Wen;Hong-Yan Zhao;Wei-Li Yao;Yuan-Yuan Zhang;Hai-Xia Fu;Yu Wang;Lan-Ping Xu;Xiao-Hui Zhang;Yuan Kong;Xiao-Jun Huang |
| 7 | A vision for the future of allogeneic hematopoietic stem cell transplantation in the next decade | 期刊论文 | Meng Lv;Norbert Claude Gorin;Xiao-jun Huang |
| 8 | The outcome of allogeneic hematopoietic stem cell transplantation among elderly patients with severe aplastic anemia and a predictive model from the Chinese Blood and Marrow Transplant Registry group | 期刊论文 | Zheng-Li Xu;Lan-Ping Xu;Yi-Cheng Zhang;Yu-Hong Zhou;Er-Lie Jiang;Jian-Ping Zhang;Bin Fu;Gui-Fang Ouyang;Xian-Min Song;Xue-Jun Zhang;Yu-Jun Dong;Nai-Nong Li;Ling Wang;Xi Zhang;Peng-Cheng He;Fan-Sheng Kong;Hui-Xia Liu;Li Liu;Lin Liu;Tai-Wu Xiao;Wen-Wei Xu;Xiao-Jun Xu;Guo-Lin Yuan;Hai Yi;Dan Yu;Li Yu;Xiao-Jun Huang |
| 9 | Outcomes of haploidentical haematopoietic stem cell transplantation for adolescent and young adults with acute myeloid leukaemia | 期刊论文 | Wen‐Xuan Huo;Qi Wen;Xiao‐Hui Zhang;Lan‐Ping Xu;Yu Wang;Chen‐Hua Yan;Huan Chen;Yu‐Hong Chen;Wei Han;Feng‐Rong Wang;Jing‐Zhi Wang;Xiao‐Jun Huang;Xiao‐Dong Mo |
| 10 | 与急性髓系白血病造血干细胞移植术后临床结局相关的生物标志物及其应用 | 专利 | 黄晓军;任悦;牛丽婷 |
| 11 | Minimal residual disease monitoring and preemptive immunotherapies for frequent 11q23 rearranged acute leukemia after allogeneic hematopoietic stem cell transplantation | 期刊论文 | Jing Liu;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Yi-Fei Cheng;Ya-Zhen Qin;Kai-Yan Liu;Xiao-Jun Huang;Xiao-Su Zhao;Xiao-Dong Mo |
| 12 | The lower relapse rate and better survival advantages of haploidentical allograft compared with HLA-matched sibling donor allografts for intermediate- and adverse-risk AML patients with pretransplantation minimal residual disease | 期刊论文 | Ming Wang;Bixia Wang;Lan-Ping Xu;Yu Wang;Xiao-Hui Zhang;Yi-fei Cheng;Yu-Qian Sun;Yuan-Yuan Zhang;Yan-Rong Liu;Ying-Jun Chang;Kai-Yan Liu;Xiao-Jun Huang |
| 13 | Cellular immunotherapy for hematological malignancy: recent progress and future perspectives | 期刊论文 | Xu Zhengli;Huang Xiaojun |
| 14 | COVID-19 was associated with the complications after allogeneic hematopoietic stem cell transplantation | 期刊论文 | Qi Wen;Ze Guo;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Yu-Qian Sun;Xiao-Jun Huang;Xiao-Dong Mo |
| 15 | The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation: 2021 update | 期刊论文 | Xiao-hui Zhang;Jing Chen;Ming-Zhe Han;He Huang;Er-lie Jiang;Ming Jiang;Yong-rong Lai;Dai-hong Liu;Qi-Fa Liu;Ting Liu;Han-yun Ren;Yong-Ping Song;Zi-min Sun;Xiao-wen Tang;Jian-min Wang;De-pei Wu;Lan-ping Xu;Xi Zhang;Dao-bin Zhou;Xiao-jun Huang |
| 16 | 芬戈莫德在制备治疗急性髓细胞白血病药物的用途 | 专利 | 黄晓军;王语晴;任悦;牛丽婷 |
| 17 | Repair of dysfunctional bone marrow endothelial cells alleviates aplastic anemia | 期刊论文 | Tang Shuqian;Xing Tong;Lyu Zhongshi;Guo Liping;Liang Mi;Li Chenyuan;Zhang Yuanyuan;Wang Yu;Xu Lanping;Zhang Xiaohui;Huang Xiaojun;Kong Yuan |
| 18 | Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study | 期刊论文 | Zheng-Li Xu;Lan-Ping Xu;De-Pei Wu;Shun-Qing Wang;Xi Zhang;Rui Xi;Su-Jun Gao;Ling-Hui Xia;Jian-Min Yang;Ming Jiang;Xin Wang;Qi-Fa Liu;Jia Chen;Ming Zhou;Xiao-Jun Huang |
| 19 | Clinical characteristics and outcomes of allogeneic hematopoietic stem cell transplantation recipients with coronavirus disease 2019 caused by the Omicron variant: a prospective, observational cohort study | 期刊论文 | Fan Shuang;Mo Xiaodong;Zhang Xiaohui;Xu Lanping;Wang Yu;Yan Chenhua;Chen Huan;Zhang Yuanyuan;Cheng Yifei;Sun Yuqian;Chen Yuhong;Chen Yao;Han Wei;Wang Jingzhi;Wang Fengrong;Xu Zhengli;Huang Xiaojun |
| 20 | Disease Risk Comorbidity Index for Patients Receiving Haploidentical Allogeneic Hematopoietic Transplantation | 期刊论文 | Xiao-Dong Mo;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Kai-Yan Liu;Xiao-Jun Huang |
| 21 | Bone marrow macrophages are involved in the ineffective hematopoiesis of myelodysplastic syndromes | 期刊论文 | Tong Xing;Wei‐Li Yao;Hong‐Yan Zhao;Jing Wang;Yuan‐Yuan Zhang;Meng Lv;Lan‐Ping Xu;Xiao‐Hui Zhang;Xiao‐Jun Huang;Yuan Kong |
| 22 | Prophylactic NAC promoted hematopoietic reconstitution by improving endothelial cells after haploidentical HSCT: a phase 3, open-label randomized trial | 期刊论文 | Yu Wang;Yuan Kong;Hong-Yan Zhao;Yuan-Yuan Zhang;Ya-Zhe Wang;Lan-Ping Xu;Xiao-Hui Zhang;Kai-Yan Liu;Xiao-Jun Huang |
| 23 | Preemptive interferon-α therapy could prevent relapse of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation: A real-world analysis | 期刊论文 | Shuang Fan;Tian-Zhong Pan;Li-Ping Dou;Yan-Min Zhao;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Xiao-Jun Huang;Xiao-Dong Mo |
| 24 | A Predicted Model for Refractory/Recurrent Cytomegalovirus Infection in Acute Leukemia Patients After Haploidentical Hematopoietic Stem Cell Transplantation | 期刊论文 | Meng-Zhu Shen;Shen-Da Hong;Jie Wang;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Kai-Yan Liu;Xiao-Jun Huang;Xiao-Dong Mo |
| 25 | G-CSF-Primed Peripheral Blood Stem Cell Haploidentical Transplantation Could Achieve Satisfactory Clinical Outcomes for Acute Leukemia Patients in the First Complete Remission: A Registered Study | 期刊论文 | Ma Yan-Ru;Zhang Xiaohui;Xu Lanping;Wang Yu;Yan Chenhua;Chen Huan;Chen Yuhong;Han Wei;Wang Fengrong;Wang Jingzhi;Liu Kaiyan;Huang Xiaojun;Mo Xiaodong |
| 26 | The impact of the combination of KIT mutation and minimal residual disease on outcome in t(8;21) acute myeloid leukemia | 期刊论文 | Ya-Zhen Qin;Qian Jiang;Yu Wang;Hao Jiang;Lan-Ping Xu;Xiang-Yu Zhao;Xiao-Hui Zhang;Kai-Yan Liu;Xiao-Jun Huang |
| 27 | Dysfunctional bone marrow endothelial progenitor cells are involved in patients with myelodysplastic syndromes | 期刊论文 | Tong Xing;Zhong-Shi Lyu;Cai-Wen Duan;Hong-Yan Zhao;Shu-Qian Tang;Qi Wen;Yuan-Yuan Zhang;Meng Lv;Yu Wang;Lan-Ping Xu;Xiao-Hui Zhang;Xiao-Jun Huang;Yuan Kong |
| 28 | Ruxolitinib is an effective salvage treatment for multidrug-resistant graft-versus-host disease after haploidentical allogeneic hematopoietic stem cell transplantation without posttransplant cyclophosphamide | 期刊论文 | Zhao Jiao-Yu;Liu Si-Ning;Xu Lan-Ping;Zhang Xiao-Hui;Wang Yu;Chen Yu-Hong;Liu Kai-Yan;Huang Xiao-Jun;Mo Xiao-Dong |
| 29 | Graft Failure in Patients With Hematological Malignancies: A Successful Salvage With a Second Transplantation From a Different Haploidentical Donor | 期刊论文 | Sun Yu-Qian;Wang Yu;Wang Feng-Rong;Yan Chen-Hua;Cheng Yi-Fei;Chen Yu-Hong;Zhang Yuan-Yuan;Han Ting-Ting;Han Wei;Suo Pan;Xu Lan-Ping;Zhang Xiao-Hui;Liu Kai-Yan;Huang Xiao-Jun |
| 30 | The role of m6A demethylase FTO in chemotherapy resistance mediating acute myeloid leukemia relapse | 期刊论文 | Zhi-Wei Zhang;Xiao-Su Zhao;Huidong Guo;Xiao-Jun Huang |
| 31 | Wilms’ tumor gene 1 is an independent prognostic factor for pediatric acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation | 期刊论文 | Dao-Xing Deng;Juan-Juan Wen;Yi-Fei Cheng;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Yu-Hong Chen;Huan Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Ya-Zhen Qin;Kai-Yan Liu;Xiao-Jun Huang;Xiao-Su Zhao;Xiao-Dong Mo |
| 32 | Prognostic factors and long-term follow-up of basiliximab for steroid-refractory acute graft-versus-host disease: Updated experience from a large-scale study | 期刊论文 | Si-Ning Liu;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Kai-Yan Liu;Xiao-Jun Huang;Xiao-Dong Mo |
| 33 | Comparison of haplo-SCT and chemotherapy for young adults with standard-risk Ph-negative acute lymphoblastic leukemia in CR1 | 期刊论文 | Meng LV;Qian Jiang;Dao-Bin Zhou;Yu Hu;Dai-Hong Liu;De-Pei Wu;Jing-Bo Wang;Hao Jiang;Jing Wang;Ying-jun Chang;Xiao-Hui Zhang;Lan-Ping Xu;Kai-Yan Liu;Xiao-Jun Huang |
| 34 | A perfect mismatch: haploidentical hematopoietic stem cell transplantation overtakes a bend | 期刊论文 | Meng Lv;Hui-Dong Guo;Xiao-jun Huang |
| 35 | Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial | 期刊论文 | Qian Jiang;Zongru Li;Yazhen Qin;Weiming Li;Na Xu;Bingcheng Liu;Yanli Zhang;Li Meng;Huanling Zhu;Xin Du;Suning Chen;Yang Liang;Yu Hu;Xiaoli Liu;Yongping Song;Lichuang Men;Zi Chen;Qian Niu;Hengbang Wang;Ming Lu;Dajun Yang;Yifan Zhai;Xiaojun Huang |
| 36 | Machine learning algorithm as a prognostic tool for Epstein-Barr virus reactivation after haploidentical hematopoietic stem cell transplantation | 期刊论文 | Shuang Fan;Hao-Yang Hong;Xin-Yu Dong;Lan-Ping Xu;Xiao-Hui Zhang;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Kai-Yan Liu;Meng-Zhu Shen;Xiao-Jun Huang;Shen-Da Hong;Xiao-Dong Mo |
| 37 | Preemptive Immunotherapy for Minimal Residual Disease in Patients With t(8;21) Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation | 期刊论文 | Shuang Fan;Meng-Zhu Shen;Xiao-Hui Zhang;Lan-Ping Xu;Yu Wang;Chen-Hua Yan;Huan Chen;Yu-Hong Chen;Wei Han;Feng-Rong Wang;Jing-Zhi Wang;Xiao-Su Zhao;Ya-Zhen Qin;Ying-Jun Chang;Kai-Yan Liu;Xiao-Jun Huang;Xiao-Dong Mo |
| 38 | Preemptive interferon-alpha treatment could protect against relapse and improve long-term survival of ALL patients after allo-HSCT | 期刊论文 | Liu Sining;Luo Xueyi;Zhang Xiaohui;Xu Lanping;Wang Yu;Yan Chenhua;Chen Huan;Chen Yuhong;Han Wei;Wang Fengrong;Wang Jingzhi;Liu Kaiyan;Huang Xiaojun;Mo Xiaodong |
| 39 | Comparison of outcomes for patients with acute myeloid leukemia undergoing haploidentical stem cell transplantation in first and second complete remission | 期刊论文 | Wen-Jing Yu;Yu-qian Sun;Lan-Ping Xu;Xiao-Hui Zhang;Kai-Yan Liu;Xiao-Jun Huang;Yu Wang |
| 40 | Hematopoietic Stem Cell Transplantation Activity in China 2020–2021 During the SARS-CoV-2 Pandemic: A Report From the Chinese Blood and Marrow Transplantation Registry Group | 期刊论文 | Lan-Ping Xu;Dao-Pei Lu;De-Pei Wu;Er-Lie Jiang;Dai-Hong Liu;He Huang;Zi-Min Sun;Nai-Nong Li;Qi-Fa Liu;Xi Zhang;Yong-Rong Lai;Yong-Ping Song;Xian-Min Song;Si-Xi Liu;Yi-Cheng Zhang;Cheng-Juan Luo;Ling-Hui Xia;Ting Niu;Yu Yu;Xiao-Hui Zhang;Xiao-Wen Tang;Yi Luo;Xiao-Jun Huang |
| 41 | GILT在作为提高急性髓系白血病患者对化疗药敏感性的作用靶点中的应用 | 专利 | 黄晓军;牛丽婷;莫晓冬 |
| 42 | Overcoming graft failure after haploidentical transplantation: Is this a possibility? | 期刊论文 | Xiao-Jun Huang |
| 43 | Adoptive therapy with CMV-specific T cells for CMV infection after haploidentical stem cell transplantation and factors affecting efficacy. | 期刊论文 | Xu-Ying Pei;Xiang-Yu Zhao;Xue-Fei Liu;Xiao-Dong Mo;Meng Lv;Lan-Ping Xu;Yu Wang;Ying-Jun Chang;Xiao-Hui Zhang;Kai-Yan Liu;Xiao-Jun Huang |
| 44 | Single-cell immune landscape of measurable residual disease in acute myeloid leukemia | 期刊论文 | Xiaodong Mo;Weilong Zhang;Guomei Fu;Yingjun Chang;Xiaohui Zhang;Lanping Xu;Yu Wang;Chenhua Yan;Mengzhu Shen;Qiuxia Wei;Changjian Yan;Xiaojun Huang |
| 45 | M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K-AKT pathway activity | 期刊论文 | Hong-Yan Zhao;Yuan-Yuan Zhang;Tong Xing;Shu-Qian Tang;Qi Wen;Zhong-Shi Lyu;Meng Lv;Yu Wang;Lan-Ping Xu;Xiao-Hui Zhang;Yuan Kong;Xiao-Jun Huang |
| 46 | Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells | 期刊论文 | Yu-Qing Wang;Yue Ren;Robert Peter Gale;Li-Ting Niu;Xiao-Jun Huang |
| 47 | Expanded clinical-grade NK cells exhibit stronger effects than primary NK cells against HCMV infection | 期刊论文 | Qian-Nan Shang;Xing-Xing Yu;Zheng-Li Xu;Yu-Hong Chen;Ting-Ting Han;Yuan-Yuan Zhang;Meng Lv;Yu-Qian Sun;Yu Wang;Lan-Ping Xu;Xiao-Hui Zhang;Xiang-Yu Zhao;Xiao-Jun Huang |
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