局部施用辛伐他汀抗生物膜及内植物感染的作用及其机制

81874010
2018
H0606.骨、关节、软组织感染
宋纯理
面上项目
研究员
北京大学
58万元
辛伐他汀;血管生成;生物膜;骨生成;内植物感染
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Single-dose local intraosseous injection of simvastatin suppresses breast cancer with tumor vascular normalization 期刊论文 Yuan W;Hai B;Ren X;Zhu J;Zhang C;Guan Z;Jia J;Wang H;Cao B;Song C
2 Gut microbiome dysbiosis alleviates the progression of osteoarthritis in mice. 期刊论文 Guan Z;Jia J;Zhang C;Sun T;Zhang W;Yuan W;Leng H;Song C
3 Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections 期刊论文 Tiantong Sun;Jie Huang;Wang Zhang;Xuanqi Zheng;Hong Wang;Jing Liu;Huijie Leng;Wanqiong Yuan;Chunli Song
4 Osteogenic effects in a rat osteoporosis model and femur defect model by simvastatin microcrystals 期刊论文 Zhu J;Zhang C;Jia J;Wang H;Leng H;Xu Y;Wu C;Zhang Q;Song C
5 A new approach to the treatment of spinal instability: Fusion or structural reinforcement without surgery? 期刊论文 Dang Lei;Zhu Jinglin;Liu Zhongjun;Liu Xiaoguang;Jiang Liang;Wei Feng;Song Chunli
6 Short-term caloric restriction induced bone loss in both axial and appendicular bones by increasing adiponectin 期刊论文 Zhu J;Liu C;Jia J;Zhang C;Yuan W;Leng H;Xu Y;Song C
7 Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method 期刊论文 Liu Qi;Bi Guofang;Chen Guiying;Guo Xuan;Tu Siqi;Tong Xiaolin;Xu Man;Liu Mengjie;Wang Bei;Jiang Hongliang;Wang Jufeng;Li Haiyan;Wang Kun;Liu Dongyang;Song Chunli
8 Incidence of and trends in hip fracture among adults in urban China A nationwide retrospective cohort study 期刊论文 Zhang C;Feng J;Wang S;Gao P;Xu L;Zhu J;Jia J;Liu L;Liu G;Wang J;Zhan S;Song C
9 局部骨骼与系统器官的内分泌对话 期刊论文 张丞贵;宋纯理
10 Pathophysiological mechanism of acute bone loss after fracture 期刊论文 Xuan-Qi Zheng;Jie Huang;Jia-Liang Lin;Chun-Li Song
11 Combination Therapy of PTH and Antiresorptive Drugs on Osteoporosis: A Review of Treatment Alternatives 期刊论文 Zhang C;Song C
12 Expression profile analysis identifies key genes as prognostic markers for metastasis of osteosarcoma 期刊论文 Guan X;Guan Z;Song C
13 Long-term pretreatment with alendronate inhibits calvarial defect healing in an osteoporotic rat model 期刊论文 Zhang Chenggui;Zhu Junxiong;Jia Jialin;Guan Zhiyuan;Sun Tiantong;Zhang Wang;Yuan Wanqiong;Wang Hong;Song Chunli
14 Effect of Single Versus Multiple Fractures on Systemic Bone Loss in Mice 期刊论文 Zhang C;Zhu J;Jia J;Guan Z;Sun T;Zhang W;Yuan W;Wang H;Leng H;Song C
15 普萘洛尔对小鼠骨折愈合的影响 期刊论文 张旺;张丞贵;管志远;黄杰;孙天童;郑烜琦;原婉琼;王红;宋纯理
16 Single intraosseous injection of simvastatin promotes endothelial progenitor cell mobilization, neovascularization, and wound healing in diabetic rats. 期刊论文 Liu C.;Zhu J.X.;Hai B.;Zhang W.;Wang H.;Leng H.J.;Xu Y.S.;Song C.L.
17 3D printed porous titanium cages filled with simvastatin hydrogel promotes bone ingrowth and spinal fusion in rhesus macaques 期刊论文 Wen Zhang;Chuiguo Sun;Junxiong Zhu;Weifang Zhang;Huijie Leng;Chunli Song
18 Once-weekly parathyroid hormone combined with ongoing long-term alendronate treatment promotes osteoporotic fracture healing in ovariectomized rats 期刊论文 Zhang C;Zhu J;Jia J;Guan Z;Sun T;Zhang W;Yuan W;Wang H;Leng H;Song C
19 静脉注射唑来膦酸所致急性期反应及他汀的预防作用 期刊论文 韩耕愚;李润庭;宋纯理
20 Single-intraosseous simvastatin injection suppresses cancers via activating CD8+ T cells 期刊论文 Wanqiong Yuan;Xiaoqing Ren;Junxiong Zhu;Jie Huang;Wang Zhang;Chenggui Zhang;Zhiyuan Guan;Hong Wang;Huijie Leng;Chunli Song
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