应用系统生物学结合PK-PD研究三芪口服液治疗膜性肾病的机制及物质基础
81774216
2017
H3108.中医内科学
徐鹏
面上项目
副研究员
广州中医药大学
54万元
三芪口服液;物质基础;系统生物学;中药药代动力学-药效学;膜性肾病
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Triptriolide antagonizes triptolide-induced nephrocyte apoptosis via inhibiting oxidative stress in vitro and in vivo | 期刊论文 | Xiaowan Wang;Ruimin Tian;Yiqi Yang;Zhaoyu Lu;Xiaodong Han;Xusheng Liu;Wei Mao;Peng Xu;Hongtao Xu;Bo Liu |
| 2 | 低毒雷公藤新多苷、其制备方法及其应用 | 专利 | 刘博;毛炜;刘旭生;徐鹏;韩晓东;周文;徐方方;刘敬功;李援朝;杨祎琦;邓金宝;吴利兰;吴云山;陈伟英;田瑞敏 |
| 3 | Metabonomic analysis of the therapeutic effects of Chinese medicine Sanqi oral solution on rats with exhaustive exercise | 期刊论文 | Peng Xu;Shasha Li;Ruimin Tian;Ling Han;Wei Mao;Li Li;Chuang Li;Yiming Wang;Guoan Luo;Nizhi Yang |
| 4 | Sanqi oral solution ameliorates renal ischemia/reperfusion injury via reducing apoptosis and enhancing autophagy: involvement of ERK/mTOR pathways | 期刊论文 | Ruimin Tian;Pinchao Wang;Lihua Huang;Chuang Li;Zhaoyu Lu;Zhisheng Lu;Aijun Wu;Kun Bao;Wei Mao;Qingming Huang;Peng Xu |
| 5 | Sanqi oral solution ameliorates renal damage and restores podocyte injury in experimental membranous nephropathy via suppression of NF kappa B | 期刊论文 | Ruimin Tian;Lijuan Wang;Aibin Chen;Lihua Huang;Xing Liang;Rongrong Wang;Wei Mao;Peng Xu;Kun Bao |
| 6 | Tripterygium glycoside fraction n2 ameliorates adriamycin-induced nephrotic syndrome in rats by suppressing apoptosis | 期刊论文 | Xiaowan Wang;Ruimin Tian;Yiqi Yang;Kai Wang;Ennian Li;Xiaodong Han;Kun Bao;Wei Mao;Hongtao Xu;Bo Liu;Peng Xu |
| 7 | Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/ HO-1 Pathway | 期刊论文 | Xiaowan Wang;Jinchu Liu;Ruimin Tian;Bidan Zheng;Chuang Li;Lihua Huang;Zhisheng Lu;Jing Zhang;Wei Mao;Bo Liu;Kun Bao;Peng Xu |
| 8 | 雷公藤内酯三醇的快速安全制备方法 | 专利 | 刘博;刘旭生;徐鹏;周文;韩晓东;毛炜;徐方方;刘敬功;李援朝;杨祎琦;邓金宝;邓远辉;吴利兰;田瑞敏;陆金健 |
| 9 | Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival | 期刊论文 | Yiqi Yang;Jian Liang;Xiaodong Han;Ruimin Tian;Xusheng Liu;Wei Mao;Hongtao Xu;Bo Liu;Peng Xu |
| 10 | 名中医杨霓芝学术思想及临证验案 | 专著 | 包崑;林启展;侯海晶;左琪;徐鹏;朴胜华;金华;张再康;毛炜 |
| 11 | Triptriolide Alleviates Lipopolysaccharide-Induced Liver Injury by Nrf2 and NF-κB Signaling Pathways | 期刊论文 | Yiqi Yang;Xiaoteng Yan;Kai Wang;Ruimin Tian;Zhaoyu Lu;Lilan Wu;Hongtao Xu;Yunshan Wu;Xusheng Liu;Wei Mao;Peng Xu;Bo Liu |
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