硅质体纳米药物载体的应用基础研究

81230036
2012
H2809.医用生物材料与仿生材料
戴志飞
重点项目
教授
北京大学
280万元
脂质体;癌症;造影剂;硅质体;纳米药物载体
2013-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Graphene oxide modified PLA microcapsules containing gold nanoparticles for ultrasonic/CT bimodal imaging guided photothermal tumor therapy 期刊论文 Jin Yushen;Wang Jinrui;Ke Hengte;Wang Shumin;Dai Zhifei
2 一种基于聚吡咯复合物的治疗诊断制剂及其制备方法 专利 戴志飞;查正宝;王金锐;曲恩泽
3 一种基于季戊四醇酯的超声造影剂及其制备方法和用途 专利 戴志飞;高闯;梁晓龙;刘仁发
4 癌症光动力治疗仪的研究进展 期刊论文 王梦玄;戴志飞
5 聚吡咯纳米粒子作为光声成像造影剂的新用途 专利 戴志飞;查正宝;梁晓龙;王金锐;李长辉;邓梓健;李妍妍;王淑敏;曲恩泽
6 一种集近红外荧光成像及化疗/光热治疗于一体的多功能纳米胶囊 专利 戴志飞;高闯;梁晓龙
7 Prussian blue nanoparticles operate as a contrast agent for enhanced photoacoustic imaging 期刊论文 Xiaolong Liang;Zijian Deng;Lijia Jing;Xiaoda Li;Changhui Li;Maomao Huang;Zhifei Dai
8 Hybrid bicelles as a pH-sensitive nanocarrier for hydrophobic drug delivery 期刊论文 Lin Li;Wang Xiaoyou;Guo Yanyu;Ren Kuan;Li Xiaoda;Jing Lijia;Yue Xiuli;Zhang Qiang;Dai Zhifei
9 普鲁士蓝壳聚糖复合纳米粒子作为基因载体的新应用 专利 戴志飞;杨勇博;冯珊珊;井立佳
10 Biocompatible polypyrrole nanoparticles as a novel organic photoacoustic contrast agent for deep tissue imaging 期刊论文 Zha Zhengbao;Deng Zijian;Li Yanyan;Li Changhui;Wang Jinrui;Wang Shumin;Qu Enze;Dai Zhifei
11 磁性普鲁士蓝纳米粒子用于癌症靶向诊疗的新应用 专利 戴志飞;付光磊;刘伟
12 分子探针在重大疾病诊疗中的应用、机遇与挑战 期刊论文 戴志飞
13 Fabrication of a Multimodal Microbubble Platform for Magnetic Resonance, Ultrasound and Fluorescence Imaging Application 期刊论文 Miao Zhaohua;Guo Caixin;Li Zhenglin;Jin Yushen;Ke Hengte;Dai Zhifei
14 Engineering of perfluorooctylbromide polypyrrole nano-/microcapsules for simultaneous contrast enhanced ultrasound imaging and photothermal treatment of cancer 期刊论文 Zha Zhengbao;Wang Jinrui;Zhang Shuhai;Wang Shumin;Qu Enze;Zhang Youyi;Dai Zhifei
15 Uniform Polypyrrole Nanoparticles with High Photothermal Conversion Efficiency for Photothermal Ablation of Cancer Cells 期刊论文 Zha Zhengbao;Yue Xiuli;Ren Qiushi;Dai Zhifei
16 A Novel Cyanine and Porphyrin based Theranostic Nanoagent for Near-infrared Fluorescence Imaging guided Synergistic Phototherapy 期刊论文 Pravin Bhattarai;Liang Xiaolong;Xu Yunxue;Dai Zhifei
17 一种阳离子复合脂质纳米盘及其制备方法和用途 专利 8..戴志飞;梁子才;李妍妍;梁晓龙;吴一荻;郑书全;靳玉慎;刘仁发;赵云辉
18 Theranostic porphyrin dyad nanoparticles for magnetic resonance imaging guided photodynamic therapy 期刊论文 Liang Xiaolong;Li Xiaoda;Jing Lijia;Yue Xiuli;Dai Zhifei
19 Multifunctional magnetic nanoparticles for magnetic resonance image-guided photothermal therapy for cancer 期刊论文 Yue Xiu-Li;Ma Fang;Dai Zhi-Fei
20 Doxorubicin and Indocyanine Green Loaded Hybrid Bicelles for Fluorescence Imaging Guided Synergetic Chemo-Photothermal Therapy 期刊论文 Li Lin;Xiaolong Liang;Yunxue Xu;Yongbo Yang;Xiaoda Li;Zhifei Dai
21 Gadolinium-chelate functionalized copper sulphide as a nanotheranostic agent for MR imaging and photothermal destruction of cancer cells 期刊论文 Zhang Shuhai;Zha Zhengbao;Yue Xiuli;Liang Xiaolong;Dai Zhifei
22 多功能超声造影剂 奖励 戴志飞;岳秀丽;王金锐;柯亨特;梁晓龙
23 Hyaluronic Acid Modified Tantalum Oxide Nanoparticles Conjugating Doxorubicin for Targeted Cancer Theranostics 期刊论文 Jin Yushen;Ma Xibo;Feng Shanshan;Liang Xiao;Dai Zhifei;Tian Jie;Yue Xiuli
24 基于碘帕醇脂质衍生物的造影剂及其制备方法与用途 专利 戴志飞;梁晓龙
25 Multifunctional Ultrasound Contrast Agents for Imaging Guided Photothermal Therapy 期刊论文 Caixin Guo;Yushen Jin;Zhifei Dai
26 一种长循环胆固醇复合脂质体及其制备方法 专利 戴志飞;李小达;梁晓龙;傅光磊;井立佳;林丽;杨勇博;冯珊珊
27 Anisotropy in Shape and Ligand-Conjugation of Hybrid Nanoparticulates Manipulates the Mode of Bio-Nano Interaction and Its Outcome 期刊论文 Wang Xiaoyou;Lin Li;Liu Renfa;Chen Min;Chen Binlong;He Bo;He Bing;Liang Xiaolong;Dai Wenbing;Zhang Hua;Wang Xueqing;Wang Yiguang;Dai Zhifei;Zhang Qiang
28 Near-infrared dye-loaded magnetic nanoparticles as photoacoustic contrast agent for enhanced tumor imaging 期刊论文 Chuang Gao;Zi-Jian Deng1;Dong Peng;Yu-Shen Jin;Yan Ma;Yan-Yan Li;Yu-Kun Zhu;Jian-Zhong Xi;Jie Tian;Chang-Hui Li;Zhi-Fei Dai
29 三磺酸基靶向酞菁及其制备方法与用途 专利 戴志飞;莫善雁;梁晓龙
30 Modulating Drug Release Rate from Partially Silica-Coated Bicellar Nanodisc by Incorporating PEGylated Phospholipid 期刊论文 Lin Li;Wang Xiaoyou;Li Xiaoda;Yang Yongbo;Yue Xiuli;Zhang Qiang;Dai Zhifei
31 癌症声动力治疗装置的研究进展 期刊论文 王梦玄;梁晓龙;陈敏;张妮丝;戴志飞
32 Design and Synthesis of Lipidic Organoalkoxysilanes for the Self-Assembly of Liposomal Nanohybrid Cerasomes with Controlled Drug Release Properties 期刊论文 Liang Xiaolong;Li Xiaoda;Jing Lijia;Xue Peng;Jiang Lingdong;Ren Qiushi;Dai Zhifei
33 Covalent attachment of Mn-porphyrin onto doxorubicin-loaded poly(lactic acid) nanoparticles for potential magnetic resonance imaging and pH-sensitive drug delivery 期刊论文 Jing Lijia;Liang Xiaolong;Li Xiaoda;Yang Yongbo;Dai Zhifei
34 Chitosan stabilized Prussian blue nanoparticles for photothermally enhanced gene delivery 期刊论文 Li Xiao-Da;Liang Xiao-Long;Ma Fang;Jing Li-Jia;Lin Li;Yang Yong-Bo;Feng Shan-Shan;Fu Guang-Lei;Yue Xiu-Li;Dai Zhi-Fei
35 吲哚菁绿J-聚集体的制备方法及应用 专利 戴志飞;刘仁发
36 Manganese (II) Chelate Functionalized Copper Sulfide Nanoparticles for Efficient Magnetic Resonance/Photoacoustic Dual-Modal Imaging Guided Photothermal Therapy 期刊论文 Liu Renfa;Jing Lijia;Peng Dong;Li Yong;Tian Jie;Dai Zhifei
37 Hyaluronic Acid Conjugated Magnetic Prussian Blue@Quantum Dot Nanoparticles for Cancer Theranostics 期刊论文 Yang Yongbo;Jing Lijia;Li Xiaoda;Lin Li;Yue Xiuli;Dai Zhifei
38 近红外荧光/超声双模式淋巴结靶向造影剂的制备方法及用途 专利 戴志飞;王金锐;曲恩泽;梁晓龙
39 Magnetic Prussian Blue Nanoparticles for Targeted Photothermal Therapy under Magnetic Resonance Imaging Guidance 期刊论文 Fu Guanglei;Liu Wei;Li Yanyan;Jin Yushen;Jiang Lingdong;Liang Xiaolong;Feng Shanshan;Dai Zhifei
40 CuInS2/ZnS Quantum Dots Conjugating Gd(III) Chelates for Near-Infrared Fluorescence and Magnetic Resonance Bimodal Imaging 期刊论文 Yang Yongbo;Lin Li;Jing Lijia;Yue Xiuli;Dai Zhifei
41 Self-assembly of Amphiphilic Janus Camptothecin-Floxuridine Conjugate into Liposome-like Nanocapsules for More Efficacious Combination Chemotherapy in Cancer 期刊论文 Xiaolong Liang;Chuang Gao;Ligang Cui;Shumin Wang;Jinrui Wang;Zhifei Dai
42 Enhancing therapeutic efficacy of combined cancer phototherapy by ultrasound-mediated in situ conversion of near-infrared cyanine/porphyrin microbubbles into nanoparticles 期刊论文 Yunxue Xu;Xiaolong Liang;Pravin Bhattarai;Yang Sun;Yiming Zhou;Shumin Wang;Wen Chen;Huiyu Ge;Jinrui Wang;Ligang Cui;Zhifei Dai
43 Chitosan Functionalized CuS Nanoparticles Boots Gene Transfection via Photothermal Effect 期刊论文 Lin Li;Li Xiaoda;Yang Yongbo;Jing Lijia;Yue Xiuli;Chen Xuzhu;Dai Zhifei
44 Nanohybrid Liposomal Cerasomes with Good Physiological Stability and Rapid Temperature Responsiveness for High Intensity Focused Ultrasound Triggered Local Chemotherapy of Cancer 期刊论文 Liang Xiaolong;Gao Jing;Jiang Lingdong;Luo Jianwen;Jing Lijia;Li Xiaoda;Jin Yushen;Dai Zhifei
45 Prussian blue nanoparticles loaded microbubbles for photothermally enhanced gene delivery through ultrasound-targeted microbubble destruction 期刊论文 Li Xiaoda;Yue Xiuli;Wang Jinrui;Liang Xiaolong;Jing Lijia;Lin Li;Yang Yongbo;Feng Shanshan;Qian Yajun;Dai Zhifei
46 PEGylated Polypyrrole Nanoparticles Conjugating Gadolinium Chelates for Dual-Modal MRI/Photoacoustic Imaging Guided Photothermal Therapy of Cancer 期刊论文 Liang Xiaolong;Li Yanyan;Li Xiaoda;Jing Lijia;Deng Zijian;Yue Xiuli;Li Changhui;Dai Zhifei
47 Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer 期刊论文 Lijia Jing;Xiaolong Liang;Zijian Deng;Shanshan Feng;Xiaoda Li;Maomao Huang;Changhui Li;Zhifei Dai
48 Stabilized Magnetic Cerasomes for Drug Delivery 期刊论文 Cao Zhong;Yue Xiuli;Li Xiaoda;Dai Zhifei
49 一种集超声/荧光双模态成像及光热/光动力治疗于一体的多功能微泡 专利 戴志飞;徐云雪;梁晓龙
50 基于季戊四醇的Janus脂质及其中间体,制备方法与用途 专利 戴志飞;梁晓龙;岳秀丽
51 Polypyrrole Hollow Microspheres as Echogenic Photothermal Agent for Ultrasound Imaging Guided Tumor Ablation 期刊论文 Zha Zhengbao;Wang Jinrui;Qu Enze;Zhang Shuhai;Jin Yushen;Wang Shumin;Dai Zhifei
52 Chitosan modified cerasomes incorporating poly (vinyl pyrrolidone) for oral insulin delivery 期刊论文 Jin Yushen;Pan Hongjie;Li Yanyan;Dai Zhifei
53 Enzyme-responsive copper sulphide nanoparticles for combined photoacoustic imaging, tumor-selective chemotherapy and photothermal therapy 期刊论文 Zha Zhengbao;Zhang Shuhai;Deng Zijian;Li Yanyan;Li Changhui;Dai Zhifei
54 一种集超声/荧光双模态成像及光动力治疗于一体的多功能微泡 专利 梁晓龙;徐云雪;郑荣琴;游宇佳;戴志飞
55 一种具有微波增敏效果的纳米脂质体及其制备方法和应用 专利 戴志飞;靳玉慎;张晓婷;安云坤
56 一种基于Janus药物共轭体的诊疗微泡的制备方法和用途 专利 戴志飞;高闯;梁晓龙
57 Hyaluronic Acid Modified Hollow Prussian Blue Nanoparticles Loading 10-hydroxycamptothecin for Targeting Thermochemotherapy of Cancer 期刊论文 Jing Lijia;Shao Shangmin;Wang Yang;Yang Yongbo;Yue Xiuli;Dai Zhifei
58 Microwave-Triggered Smart Drug Release from Liposomes Coencapsulating doxorubicin and salt for local combined hyperthermia and chemotherapy of cancer 期刊论文 Yushen Jin;Xiaolong Liang;Yunkun An;Zhifei Dai
59 Targeted delivery of CuS nanoparticles through ultrasound image-guided microbubble destruction for efficient photothermal therapy 期刊论文 Zha Zhengbao;Wang Shumin;Zhang Shuhai;Qu Enze;Ke Hengte;Wang Jinrui;Dai Zhifei
60 Nanomedicine has opened new avenues for cancer diagnosis and therapy 期刊论文 Zhi-Fei Dai
61 一种用于肿瘤荧光成像及光热/光动力治疗的多功能纳米粒子 专利 戴志飞;梁晓龙;徐云雪;Pravin Bhattarai
62 一种靶向乳腺癌干细胞的洛伐他汀硅质体 专利 邓锡云;戴志飞;宋柳江
63 Advances in Nanotheranostics (Volume I and II) 专著 戴志飞
64 Gold Nanoshelled Liquid Perfluorocarbon Magnetic Nanocapsules: a Nanotheranostic Platform for Bimodal Ultrasound/Magnetic Resonance Imaging Guided Photothermal Tumor Ablation 期刊论文 Hengte Ke;Jinrui Wang;Sheng Tong;Yushen Jin;Shumin Wang;Enze Qu;Gang Ba;Zhifei Dai
65 Encapsulating tantalum oxide into polypyrrole nanoparticles for X-ray CT/photoacoustic bimodal imaging-guided photothermal ablation of cancer 期刊论文 Yushen Jin;Yanyan Li;Xibo Ma;Zhengbao Zha;Liangliang Shi;Jie Tian;Zhifei Dai
66 Doping Hydroxylated Cationic Lipid into PEGylated Cerasome Boosts in Vivo siRNA Transfection Efficacy 期刊论文 Li Yanyan;Zheng Shuquan;Liang Xiaolong;Jin Yushen;Wu Yidi;Bai Huichen;Liu Renfa;Dai Zhifei;Liang Zicai;Shi Tiejun
67 Porphyrin-loaded nanoparticles for cancer theranostics 期刊论文 Zhou Yiming;Liang Xiaolong;Dai Zhifei
68 Mn-porphyrin Conjugated Au Nanoshells Encapsulating Doxorubicin for Potential Magnetic Resonance Imaging and Light Triggered Synergistic Therapy of Cancer 期刊论文 Jing Lijia;Liang Xiaolong;Li Xiaoda;Lin Li;Yang Yongbo;Yue Xueli;Dai Zhifei
69 Recent advances in liposomal nanohybrid cerasomes as promising drug nanocarriers 期刊论文 Xiuli Yue;Zhifei Dai
70 Cyanine based Nanoprobes for Cancer Theranostics 期刊论文 Bhattarai Pravin;Dai Zhifei
71 Nano-sized Indocyanine Green J-aggregate as a One-component Theranostic Agent. Nanotheranostics 期刊论文 Renfa Liu;Jie Tang;Yunxue Xu;Yiming Zhou;Zhifei Dai
72 Liposomal nanohybrid cerasomes for controlled insulin release 期刊论文 Jin Yushen;Li Yanyan;Pan Hongjie;Dai Zhifei
73 177Lu-Labeled Cerasomes Encapsulating Indocyanine Green for Cancer Theranostics 期刊论文 Jing Lijia;Shi Jiyun;Fan Di;Li Yaqian;Liu Renfa;Dai Zhifei;Wang Fan;Tian Jie
74 普鲁士蓝纳米粒子作为光声成像造影剂的新用途 专利 戴志飞;梁晓龙;李长辉;邓梓健;井立佳;黄毛毛;李小达
75 温敏复合脂质体用于水溶性及两亲性抗癌药物的控制释放 专利 戴志飞;梁晓龙;蒋灵冬;井立佳
76 Liposomal nanotechnology for cancer theranostics 期刊论文 Xiuli Yue;Zhifei Dai
77 Gold Nanoshelled Liquid Perfluorocarbon Nanocapsules for Combined Dual Modal Ultrasound/CT Imaging and Photothermal Therapy of Cancer 期刊论文 Ke Hengte;Yue Xiuli;Wang Jinrui;Xing Sen;Zhang Qian;Dai Zhifei;Tian Jie;Wang Shumin;Jin Yushen
78 Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy 期刊论文 Ma Yan;Tong Sheng;Bao Gang;Gao Chuang;Dai Zhifei
79 一种具有超长持续时间的超声造影剂及其制备方法 专利 戴志飞;刘仁发;梁晓龙;王金锐
80 Advances in multifunctional nano-sized CT contrast agents (in Chinese) 期刊论文 Xiaoting Zhang;Zhifei Dai
81 Near-infrared light-activatable polymeric nanoformulations for combined therapy and imaging of cancer 期刊论文 Xiuli Yue;Qiang Zhang;Zhifei Dai
82 Imaging guided photothermal therapy using iron oxide loaded poly(lactic acid) microcapsules coated with graphene oxide 期刊论文 Li Xiao-Da;Liang Xiao-Long;Yue Xiu-Li;Wang Jin-Rui;Li Chang-Hui;Deng Zi-Jian;Jing Li-Jia;Lin Li;Qu En-Ze;Wang Shu-Min;Wu Chun-Long;Wu Hua-Xing;Dai Zhi-Fei
83 一种基于叔丁醇/水混合液的制备微泡超声造影剂的方法 专利 戴志飞;刘仁发;梁晓龙;王金锐
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