真核生物基因组转录因子聚集区域的演化规律及其与肿瘤的关系
61873276
2018
F0305.生物、医学信息系统与技术
伯晓晨
面上项目
研究员
中国人民解放军军事科学院军事医学研究院
63万元
演化;染色质结构;转录因子聚集区域;多组学
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | New insights on human essential genes based on integrated analysis and the construction of the HEGIAP web-based platform | 期刊论文 | Ghen Hebing;Zhang Zhuo;Jiang Shuai;Li Ruijiang;Li Wanying;Zhao Chenghui;Hong Hao;Huang Xin;Li Hao;Bo Xiaochen |
| 2 | High-resolution annotation of the mouse preimplantation embryo transcriptome using long-read sequencing | 期刊论文 | Yunbo Qiao;Chao Ren;Shisheng Huang;Jie Yuan;Xingchen Liu;Jiao Fan;Jianxiang Lin;Susu Wu;Qiuzhen Chen;Xiaochen Bo;Xiangyang Li;Xingxu Huang;Zhen Liu;Wenjie Shu |
| 3 | Exploration of prognosis-related microRNA and transcription factor co-regulatory networks across cancer types | 期刊论文 | Ruijiang Li;Shuai Jiang;Wanying Li;Hao Hong;Chenghui Zhao;Xin Huang;Zhuo Zhang;Hao Li;Hebing Chen;Xiaochen Bo |
| 4 | Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance | 期刊论文 | Yang Ding;Yang Zheng;Junting Wang;Hao Li;Chenghui Zhao;Huan Tao;Yaru Li;Kang Xu;Xin Huang;Ge Gao;Hebing Chen;Xiaochen Bo |
| 5 | 染色体间易位识别方法、装置、电子设备及可读存储介质 | 专利 | 陈河兵;洪浩;李昊;江帅;黄昕;杜桂芳;陶欢;孙昱;王军婷;许康;李雅儒;伯晓晨 |
| 6 | 一种染色体变异检测方法、装置、电子设备及介质 | 专利 | 陈河兵;杨骞;李昊;伯晓晨 |
| 7 | DeepHiC: A generative adversarial network for enhancing Hi-C data resolution. | 期刊论文 | Hong Hao;Jiang Shuai;Li Hao;Du Guifang;Sun Yu;Tao Huan;Quan Cheng;Zhao Chenghui;Li Ruijiang;Li Wanying;Yin Xiaoyao;Huang Yangchen;Li Cheng;Chen Hebing;Bo Xiaochen |
| 8 | Inferring transcription factor regulatory networks from single-cell ATAC-seq data based on graph neural networks | 期刊论文 | Hao Li;Yu Sun;Hao Hong;Xin Huang;Huan Tao;Qiya Huang;Longteng Wang;Kang Xu;Jingbo Gan;Chen Hebing;Xiaochen Bo |
| 9 | Ionizing radiation damage and repair from 3D-genomic perspective | 期刊论文 | Yang Zheng;Hao Li;Xiaochen Bo;Hebing Chen |
| 10 | Regulatory patterns analysis of transcription factor binding site clustered regions and identification of key genes in endometrial cancer | 期刊论文 | Xiaohan Tang;Junting Wang;Huan Tao;Lin Yuan;Guifang Du;Yang Ding;Kang Xu;Xuemei Bai;Yaru Li;Yu Sun;Xin Huang;Xiushuang Zheng;Qianqian Li;Bowen Gong;Yang Zheng;Jingxuan Xu;Xiang Xu;Zhe Wang;Xiaochen Bo;Meisong Lu;Hao Li;Hebing Chen |
| 11 | Computational methods for the prediction of chromatin interaction and organization using sequence and epigenomic profiles | 期刊论文 | Huan Tao;Hao Li;Kang Xu;Hao Hong;Shuai Jiang;Guifang Du;Junting Wang;Yu Sun;Xin Huang;Yang Ding;Fei Li;Xiaofei Zheng;Hebing Chen;Xiaochen Bo |
| 12 | dbEmbryo multi-omics database for analyses of synergistic regulation in early mammalian embryo development | 期刊论文 | Xin Huang;Xiaohan Tang;Xuemei Bai;Honglei Li;Huan Tao;Junting Wang;Yaru Li;Yu Sun;Yang Zheng;Xiang Xu;Longteng Wang;Yang Ding;Meisong Lu;Pingkun Zhou;Xiaochen Bo;Hao Li;Hebing Chen |
| 13 | The accessible promoter-mediated supplementary effect of host factors provides new insight into the tropism of SARS-CoV-2 | 期刊论文 | Guifang Du;Xiang Xu;Junting Wang;Xuejun Wang;Yang Ding;Fei Li;Yu Sun;Huan Tao;Yawen Luo;Hao Li;Xiaochen Bo;Hebing Chen |
| 14 | 癌症基因组Hi-C数据仿真方法、装置和电子设备 | 专利 | 陈河兵;洪浩;李昊;江帅;杜桂芳;陶欢;孙昱;王军婷;许康;伯晓晨 |
| 15 | 一种识别合子型基因激活ZGA基因的方法及装置 | 专利 | 李昊;陈河兵;黄昕;孙昱;杜桂芳;王军婷;陶欢;许康;伯晓晨 |
| 16 | The hierarchical folding dynamics of topologically associating domains are closely related to transcriptional abnormalities in cancers | 期刊论文 | Du Guifang;Li Hao;Ding Yang;Jiang Shuai;Hong Hao;Gan Jingbo;Wang Longteng;Yang Yuanping;Li Yinyin;Huang Xin;Sun Yu;Tao Huan;Li Yaru;Xu Xiang;Zheng Yang;Wang Junting;Bai Xuemei;Xu Kang;Li Yaoshen;Jiang Qi;Li Cheng;Chen Hebing;Bo Xiaochen |
| 17 | Spatial density of open chromatin: an effective metric for the functional characterization of topologically associated domains. | 期刊论文 | Shuai Jiang;Hao Li;Hao Hong;Guifang Du;Xin Huang;Yu Sun;Junting Wang;Huan Tao;Kang Xu;Cheng Li;Yang Chen;Hebing Chen;Xiaochen Bo |
| 18 | 一种单细胞的转录因子调控网络预测方法及装置 | 专利 | 李昊;陈河兵;孙昱;洪浩;黄昕;陶欢;黄琦雅;伯晓晨 |
| 19 | 基于ATAC测序数据筛选子宫内膜癌关键基因的方法及应用 | 专利 | 卢美松;陈河兵;汤小晗;王军婷;李昊;陶欢;伯晓晨 |
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