乙型肝炎病毒x蛋白激活Rho信号途径诱发肝细胞恶性转化分子机制的定量蛋白质组学研究

31470809
2014
C0509.生物学过程与代谢
徐平
面上项目
研究员
中国人民解放军军事科学院军事医学研究院
85万元
肝细胞癌;基于细胞培养的同位素标记;侵袭转移;乙型肝炎病毒x蛋白;小G蛋白
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Enhanced Purification of Ubiquitinated Proteins by Engineered Tandem Hybrid Ubiquitin-binding Domains (ThUBDs) 期刊论文 Gao Yuan;Li Yanchang;Zhang Chengpu;Zhao Mingzhi;Liu Zexian;Chang Lei;Peng Junmin;Xu Ping
2 Digging for Missing Proteins Using Low-Molecular-Weight Protein Enrichment and a "Mirror Protease" Strategy 期刊论文 He Cuitong;Sun Jinshuai;Shi Jiahui;Wang Yihao;Zhao Jialing;Wu Shujia;Chang Lei;Gao Huiying;Liu Fengsong;Lv Zhitang;He Fuchu;Zhang Yao;Xu Ping
3 High-coverage proteomics reveals methionine auxotrophy in Deinococcus radiodurans 期刊论文 Zhou Yanxia;Shen Pan;Lan Qiuyan;Deng Chen;Zhang Yao;Li Yanchang;Wei Wei;Wang Yihao;Xu Ping
4 Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism 期刊论文 Xu Zhongwei;Zhai Linghui;Yi Tailong;Gao Huiying;Fan Fengxu;Li Yanchang;Wang Youliang;Li Ning;Xing Xiaohua;Xu Ping
5 Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells 期刊论文 Xie Qi;Fan Fengxu;Wei Wei;Liu Yang;Xu Zhongwei;Zhai Linhui;Qi Yingzi;Wu Junzhu;Xu Ping
6 Proteomic Analysis and NIR-II Imaging of MCM2 Protein in Hepatocellular Carcinoma 期刊论文 Yang Jing;Xie Qi;Zhou Hui;Chang Lei;Wei Wei;Wang Yin;Li Hong;Deng Zixin;Xiao Yuling;Wu Junzhu;Xu Ping;Hong Xuechuan
7 脂肪分化相关蛋白作为HBV-HCC患者筛查标记物的新用途 专利 徐平;徐忠伟;翟琳辉;衣泰龙;樊锋旭;李衍常;李宁;常蕾
8 Deep Coverage Proteomics Identifies More Low-Abundance Missing Proteins in Human Testis Tissue with Q-Exactive HF Mass Spectrometer 期刊论文 Wei Wei;Luo Weijia;Wu Feilin;Peng Xuehui;Zhang Yao;Zhang Manli;Zhao Yan;He Fuchu;Xu Ping
9 Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae 期刊论文 He Cuitong;Jia Chenxi;Zhang Yao;Xu Ping
10 Searching Missing Proteins Based on the Optimization of Membrane Protein Enrichment and Digestion Process 期刊论文 Zhao Mingzhi;Wei Wei;Cheng Long;Zhang Yao;Wu Feilin;He Fuchu;Xu Ping
11 Quantitative proteomics reveals FLNC as a potential progression marker for the development of hepatocellular carcinoma 期刊论文 Qi Yingzi;Xu Feng;Chen Lingsheng;Li Yanchang;Xu Zhongwei;Zhang Yao;Liu Yinkun;Xu Ping
12 一种重组乙酰化赖氨酸精氨酸N端蛋白酶及其制备方法和应用 专利 徐平;王富强;张俊令;赵明治;常蕾
13 一种重组乙酰化阳离子型胰蛋白酶的制备方法及其应用 专利 赵明治;徐平;吴飞林
14 A rapid and easy protein N-terminal profiling strategy using (N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl) phosphonium bromide ( TMPP) labeling and StageTip 期刊论文 Li Yanchang;Wang Zhiqiang;Zhou Wenjing;Zhang Kun;Ma Jia;Wu Feilin;Hong Xuechuan;Deng Zixin;Xu Ping
15 人工构建的杂种泛素结合结构域多肽及其应用 专利 徐平;高媛;李衍常;赵明治;王京伟;常蕾
16 一种赖氨酰肽链内肽酶的原核重组表达与制备方法 专利 赵明治;徐平;吴飞林;常蕾
17 iTRAQ-Based Membrane Proteomics Reveals Plasma Membrane Proteins Change During HepaRG Cell Differentiation 期刊论文 Zhao Mingzhi;Xu Feng;Wu Feilin;Yu Debin;Su Na;Zhang Yao;Cheng Long;Xu Ping
18 蛋白激酶mTOR的S2481位点磷酸化作为肿瘤用药的标志物 专利 徐平;薛宇;徐锋;刘泽先;徐忠伟
19 Hepatitis B Virus X Protein Stimulates Proliferation, Wound Closure and Inhibits Apoptosis of HuH-7 Cells via CDC42 期刊论文 Xu Yongru;Qi Yingzi;Luo Jing;Yang Jing;Xie Qi;Deng Chen;Xu Feng;Li Xiangping;Xu Ping
20 Multi-Protease Strategy Identifies Three PE2 Missing Proteins in Human Testis Tissue 期刊论文 Wang Yihao;Chen Yang;Zhang Yao;Wei Wei;Li Yanchang;Zhang Tao;He Fuchu;Gao Yue;Xu Ping
21 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer 期刊论文 Peng Xuehui;Xu Feng;Liu Shu;Li Suzhen;Huang Qingbo;Chang Lei;Wang Lei;Xu Ping
22 Multiproteases Combined with High-pH Reverse-Phase Separation Strategy Verified Fourteen Missing Proteins in Human Testis Tissue 期刊论文 Sun Jinshuai;Shi Jiahui;Wang Yihao;Chen Yang;Li Yanchang;Kong Degang;Chang Lei;Liu Fengsong;Lv Zhitang;Zhou Yue;He Fuchu;Zhang Yao;Xu Ping
23 Digging for Missing Proteins Using Low-Molecular-Weight Protein Enrichment and a "Mirror Protease" Strategy 期刊论文 He Cuitong;Sun Jinshuai;Shi Jiahui;Wang Yihao;Zhao Jialing;Wu Shujia;Chang Lei;Gao Huiying;Liu Fengsong;Lv Zhitang;He Fuchu;Zhang Yao;Xu Ping
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