过氧化物还原酶Peroxiredoxin 2调控ROS-ASK1-p38 MAPK信号通路抑制蛛网膜下腔出血后神经元铁死亡的机制研究
81901203
2019
H0906.脑血管结构、功能异常及相关疾病
鲁悦
青年科学基金项目
主治医师
南京大学
21万元
蛛网膜下腔出血;蛋白相互作用;活性氧自由基;铁死亡;过氧化物还原酶2
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Knock-Down of CD24 in Astrocytes Aggravates Oxyhemoglobin-Induced Hippocampal Neuron Impairment | 期刊论文 | Xiang-Xin Chen;Tao Tao;Sen Gao;Han Wang;Xiao-Ming Zhou;Yong-Yue Gao;Chun-Hua Hang;Wei Li |
| 2 | DHEA Attenuates Microglial Activation via Induction of JMJD3 in Experimental Subarachnoid Haemorrhage | 期刊论文 | Tao Tao;Guang-Jie Liu;Xuan Shi;Yan Zhou;Yue Lu;Yong-Yue Gao;Xiang-Sheng Zhang;Han Wang;Ling-Yun Wu;Chun-Lei Chen;Zong Zhuang;Wei Li;Chun-Hua Hang |
| 3 | Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/NRF2/Prx2/ASK1/p38 after traumatic brain injury in mice | 期刊论文 | Xiang‐Sheng Zhang;Yue Lu;Wen Li;Tao Tao;Lei Peng;Wei‐Han Wang;Sen Gao;Cang Liu;Zong Zhuang;Da‐Yong Xia;Chun‐Hua Hang;Wei Li |
| 4 | High Expression of PDK4 Could Play a Potentially Protective Role by Attenuating Oxidative Stress after Subarachnoid Hemorrhage | 期刊论文 | Xuan Gao;Yong-Yue Gao;Ling-Yun Wu;Zheng Peng;X-F Liu;Xiang-Xin Chen;Sen Gao;Hua-Sheng Zhang;Yue Lu;Chun-Hua Hang;Zong Zhuang;Wei Li |
| 5 | Astrocytic CD24 Protects Neuron from Recombinant High-Mobility Group Box 1 Protein(rHMGB1)-Elicited Neuronal Injury | 期刊论文 | Cong Pang;Sen Gao;Xun-Zhi Liu;Xiao-Jian Li;Zheng Peng;Hua-Sheng Zhang;Yan Zhou;Xiang-Xin Chen;Tao Tao;Yue Lu;Wei Li;Chun-Hua Hang |
| 6 | Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway | 期刊论文 | Xiang-Sheng Zhang;Yue Lu;Tao Tao;Han Wang;Guang-Jie Liu;Xun-Zhi Liu;Cang Liu;Da-Yong Xia;Chun-Hua Hang;Wei Li |
| 7 | Pterostilbene Attenuates Subarachnoid Hemorrhage-Induced Brain Injury through the SIRT1-Dependent Nrf2 Signaling Pathway. | 期刊论文 | Zhang Zihuan;Fang Jincheng;Zhou Jiawang;Ding Fei;Zhou Gang;Zhao Xintong;Zhuang Zong;Lu Yue |
| 8 | Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhage | 期刊论文 | Tao Tao;Xiangxin Chen;Yan Zhou;Qiang Zheng;Sen Gao;Jinwei Wang;Pengfei Ding;Xiaojian Li;Zheng Peng;Yue Lu;Yongyue Gao;Zong Zhuang;Chun-hua Hang;Wei Li |
| 9 | Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury | 期刊论文 | Han Wang;Xiao-Ming Zhou;Ling-Yun Wu;Guang-Jie Liu;Wei-Dong Xu;Xiang-Sheng Zhang;Yong-Yue Gao;Tao Tao;Yan Zhou;Yue Lu;Juan Wang;Chu-Lei Deng;Zong Zhuang;Chun-Hua Hang;Wei Li |
| 10 | 以问题为基础教学法在颅内动脉瘤外科治疗临床教学中的应用 | 期刊论文 | 鲁悦;陶涛;庄宗;李伟;杭春华 |
| 11 | Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury | 期刊论文 | Guang-Jie Liu;Tao Tao;Han Wang;Yan Zhou;Xuan Gao;Yong-Yue Gao;Chun-Hua Hang;Wei Li |
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