基于抗病毒蛋白SAMHD1的HIV与宿主细胞间博弈的新分子机制研究
81871639
2018
H2104.逆转录病毒与感染
籍晓云
面上项目
教授
南京大学
57万元
结构与功能;抗病毒蛋白;病毒拮抗;蛋白降解;蛋白核酸结合
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation | 期刊论文 | Abula Abudureyimu;Li Xiaona;Quan Xing;Yang Tingting;Liu Yue;Guo Hangtian;Li Tinghan;Ji Xiaoyun |
| 2 | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition | 期刊论文 | Yue Liu;Abudureyimu Abula;Haonan Xiao;Hangtian Guo;Tinghan Li;Le Zheng;Biqing Chen;Henry C. Nguyen;Xiaoyun Ji |
| 3 | Structures of Omicron spike complexes and implications for neutralizing antibody development | 期刊论文 | Hangtian Guo;Yan Gao;Tinghan Li;Tingting Li;Yuchi Lu;Le Zheng;Yue Liu;Tingting Yang;Feiyang Luo;Shuyi Song;Wei Wang;Xiuna Yang;Henry C. Nguyen;Hongkai Zhang;Ailong Huang;Aishun Jin;Haitao Yang;Zihe Rao;Xiaoyun Ji |
| 4 | SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis | 期刊论文 | Meijing Wang;Tinghan Li;Zijun Ouyang;Kai Tang;Yuyu Zhu;Chenglin Song;Haiyan Sun;Bin Yu;Xiaoyun Ji;Yang Sun |
| 5 | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1–Nup98 Complex to Compete With mRNA Nuclear Export | 期刊论文 | Tinghan Li;Yibo Wen;Hangtian Guo;Tingting Yang;Haitao Yang;Xiaoyun Ji |
| 6 | Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis | 期刊论文 | Mengmeng Lin;Wen Cui;Hongliang Tian;Yan Zhang;Chen Chen;Xiaoyun Yang;Heng Chi;Zhongyu Mu;Cheng Chen;Zefang Wang;Xiaoyun Ji;Haitao Yang;Zhi Lin |
| 7 | Enhancement of Escherichia coli Ribonuclease R Cytosine-Sensitive Activity by Single Amino Acid Substitution | 期刊论文 | Abudureyimu Abula;Tingting Yang;Yingxin Zhang;Tinghan Li;Xiaoyun Ji |
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