CREB-NR2B反馈调控过程对脑衰老相关胰岛素抵抗与TGF-β信号通路紊乱对话的作用及其在术后认知功能障碍中的意义

81801380
2018
H1902.衰老相关疾病
赵鑫
青年科学基金项目
主治医师
南京大学
21万元
胰岛素抵抗;术后认知功能障碍;衰老;转化生长因子-β信号通路;cAMP应答元件结合蛋白
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The role of 5-HT7R in the memory impairment induced by long-term isoflurane anesthesia in youg mice 期刊论文 Tiantian Liu;Jia Song;Qingyun Zhou;Shuaishuai Chu;Yujia Liu;Xin Zhao;Zhengliang Ma;Tianjiao Xia;Xiaoping Gu
2 Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice 期刊论文 Liangyu Peng;Xin Fang;Fangxia Xu;Shuai Liu;Yue Qian;Xiangdan Gong;Xin Zhao;Zhengliang Ma;Tianjiao Xia;Xiaoping Gu
3 Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice 期刊论文 Fang Xin;Xia Tianjiao;Xu Fangxia;Wu Hao;Ma Zhengliang;Zhao Xin;Gu Xiaoping
4 Protective effects of grape seed procyanidin on isoflurane-induced cognitive impairment in mice 期刊论文 Gong X;Xu L;Fang X;Zhao X;Du Y;Wu H;Qian Y;Ma Z;Xia T;Gu X
5 Time-restricted feeding alters isofluraneinduced memory deficits 期刊论文 Song Jia;Chu Shuaishuai;Fang Xin;Xu Fangxia;Zhang Peng;Zhao Xin;Ma Zhengliang;Xia Tianjiao;Gu Xiaoping
6 Photoacoustic treatment mitigates cognitive dysfunction in a model of sleep-wake rhythm disturbance 期刊论文 Xing Fang;Fang Xin;Gong Xiang-Dan;Zhao Xin;Du Ying;Ma Zheng-Liang;Gu Xiao-Ping;Xia Tian-Jiao
7 Green tea polyphenols improve isoflurane-induced cognitive impairment via modulating oxidative stress 期刊论文 Song Yuting;Li Xiuxiu;Gong Xiangdan;Zhao Xin;Ma Zhengliang;Xia Tianjiao;Gu Xiaoping
8 GLYX-13 pretreatment ameliorates long-term isoflurane exposure-induced cognitive impairment in mice 期刊论文 Liu Huan;Gong Xiang-Dan;Zhao Xin;Qian Yue;Gu Xiao-Ping;Xia Tian-Jiao
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