KCNQ/M电压门控钾通道在骨癌痛发生中的作用及其机制研究

31171063
2011
C0904.感觉与运动系统神经生物学
邢国刚
面上项目
教授
北京大学
68万元
DRG神经元;骨癌痛;NGF;KCNQ/M通道;外周敏化
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation. 期刊论文 Song Li|Xiao-Dan Liu|You Wan|Guo-Gang Xing (邢国刚)|
2 Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats 期刊论文 Jie Cai|Xue-Jing Kang|You Wan|Guo-Gang Xing|
3 BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation 期刊论文 Song Li|Xiao-Dan Liu|You Wan|Guo-Gang Xing|
4 Down-regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia, whereas up-regulation of the channel by Sheng-Jing-San treatment improves the sperm motility of asthenozoospermia in rats 期刊论文 Bin Zhang|Jie Cai|Wei Sun|Guo-Gang Xing|
5 Upregulation of P2X3 receptors by neuronal calcium sensor protein VILIP-1 in dorsal root ganglions contributes to the bone cancer pain in rats 期刊论文 You Wan|De-Hua Chui|Ji-Sheng Han|Guo-Gang Xing|
6 慢性疼痛与抑郁关系的研究进展 期刊论文 闻洁曦|邢国刚|
7 Down-regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia, whereas up-regulation of the channel by Sheng-Jing-San treatment improves the sperm motility of asthenozoospermia in rats 期刊论文 Bin Zhang|Jie Cai|Wei Sun|Guo-Gang Xing|
8 抑郁症的生物学机制研究进展 期刊论文 郭雨欣|邢国刚|
9 KCNQ/M (Kv7) 钾通道参与骨癌痛大鼠中枢敏化的电生理学研究. 期刊论文 蔡捷|崔彦军|邢国刚|
10 电压门控型钠离子通道Nav1.8 在骨癌大鼠DRG 神经元细胞膜上的表达上调. 期刊论文 蔡 捷|万 有|韩济生|邢国刚|
11 The antiallodynic action of pregabalin may depend on the suppression of spinal neuronal hyperexcitability in rats with spared nerve injury 期刊论文 Jie Cai|Xiang-Yang Guo|Xiu-Li Meng|Guo-Gang Xing|
12 Interleukin-6-mediated functional upregulation of TRPV1 receptors in dorsal root ganglion neurons through the activation of JAK/PI3K signaling pathway: roles in the development of bone cancer pain in a rat model 期刊论文 Song Li|Xiao-Dan Liu|Ji-Sheng Han|Guo-Gang Xing|
13 Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model 期刊论文 Jie Cai|You Wan|Ji-Sheng Han|Guo-Gang Xing|
14 Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model 期刊论文 Jie Cai|You Wan|Ji-Sheng Han|Guo-Gang Xing|
15 脊神经结扎诱导大鼠脊髓背角SFKs-Y416p 和GluN2B 表达增加. 期刊论文 蔡捷|万有|崔颜军|邢国刚|
16 Suppression of KCNQ/M (Kv7) potassium channels in the spinal cord contributes to the sensitization of dorsal horn WDR neurons and pain hypersensitivity in a rat model of bone cancer pain 期刊论文 Xiao-Dan Liu|Song Li|Juan Ren|Guo-Gang Xing|
17 Functional upregulation of nav1.8 sodium channels on the membrane of dorsal root ganglia neurons contributes to the development of cancer-induced bone pain 期刊论文 Dong Fang|Jie Cai|You Wan|Guo-Gang Xing|
18 Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain 期刊论文 Jie Cai|You Wan|Ji-Sheng Han|Guo-Gang Xing|
19 鞘内应用普瑞巴林对神经病理性疼痛大鼠的镇痛作用及其电生理学机制研究. 期刊论文 丁蕾|邢国刚|郭向阳|孟秀丽|
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