长链非编码RNA AK036689在阿尔茨海默病早期海马突触环路功能障碍中的作用
31571039
2015
C0901.分子与细胞神经生物学
朱铃强
面上项目
教授
华中科技大学
64万元
非编码RNA;阿尔茨海默病;突触可塑性;海马环路
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1. | 期刊论文 | Shu Shu;Zhu Houze;Tang Na;Chen Wenting;Li Xinyan;Li Hao;Pei Lei;Liu Dan;Mu Yangling;Tian Qing;Zhu Ling-Qiang;Lu Youming |
| 2 | A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer's Disease. | 期刊论文 | Wang Xiong;Liu Dan;Huang He-Zhou;Wang Zhi-Hao;Hou Tong-Yao;Yang Xin;Pang Pei;Wei Na;Zhou Ya-Fan;Dupras Marie-Josee;Calon Frederic;Wang Yu-Tian;Man Heng-Ye;Chen Jian-Guo;Wang Jian-Zhi;Hebert Sebastien S;Lu Youming;Zhu Ling-Qiang |
| 3 | Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes. | 期刊论文 | Xie Ao-Ji;Liu En-Jie;Huang He-Zhou;Hu Yu;Li Ke;Lu Youming;Wang Jian-Zhi;Zhu Ling-Qiang |
| 4 | Long Non-coding RNAs, Novel Culprits, or Bodyguards in Neurodegenerative Diseases | 期刊论文 | Ding-Qi Wang;Peng Fu;Chengye Yao;Ling-Shuang Zhu;Tong-Yao Hou;Jian-Guo Chen;Youming Lu;Dan Liu;Ling-Qiang Zhu |
| 5 | Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. | 期刊论文 | Zhu Houze;Yan Huanhuan;Tang Na;Li Xinyan;Pang Pei;Li Hao;Chen Wenting;Guo Yu;Shu Shu;Cai You;Pei Lei;Liu Dan;Luo Min-Hua;Man Hengye;Tian Qing;Mu Yangling;Zhu Ling-Qiang;Lu Youming |
| 6 | A novel mechanism of memory loss in Alzheimer's disease mice via the degeneration of entorhinal-CA1 synapses. | 期刊论文 | Yang X;Yao C;Tian T;Li X;Yan H;Wu J;Li H;Pei L;Liu D;Tian Q;Zhu L-Q;Lu Y |
| 7 | The Peptide-Directed Lysosomal Degradation of CDK5 Exerts Therapeutic Effects against Stroke | 期刊论文 | Zhou Ya Fan;Wang Jing;Deng Man Fei;Chi Bin;Wei Na;Chen Jian Guo;Liu Dan;Yin Xiaoping;Lu Youming;Zhu Ling Qiang |
| 8 | MicroRNA-26a/Death-Associated Protein Kinase 1 Signaling Induces Synucleinopathy and Dopaminergic Neuron Degeneration in Parkinson's Disease | 期刊论文 | Su Ying;Deng Man Fei;Xiong Wan;Xie Ao Ji;Guo Jifeng;Liang Zhi Hou;Hu Bo;Chen Jian Guo;Zhu Xiongwei;Man Heng Ye;Lu Youming;Liu Dan;Tang Beisha;Zhu Ling Qiang |
| 9 | MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats | 期刊论文 | Ouyang Yetong;Li Dongling;Wang Han;Wan Zhigang;Luo Qinghua;Zhong Yuqin;Yin Min;Qing Zhengfang;Li Zhengyu;Bao Bing;Chen Zhiying;Yin Xiaoping;Zhu Ling Qiang |
| 10 | Synaptic Dysfunction in Alzheimer's Disease: Abeta, Tau, and Epigenetic Alterations. | 期刊论文 | Li Ke;Wei Qing;Liu Fang-Fang;Hu Fan;Xie Ao-Ji;Zhu Ling-Qiang;Liu Dan |
| 11 | Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease. | 期刊论文 | Liu Dan;Tang Hui;Li Xin-Yan;Deng Man-Fei;Wei Na;Wang Xiong;Zhou Ya-Fan;Wang Ding-Qi;Fu Peng;Wang Jian-Zhi;Hebert Sebastien S;Chen Jian-Guo;Lu Youming;Zhu Ling-Qiang |
| 12 | Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR-132/MeCP2 pathway | 期刊论文 | Xie Ao Ji;Hou Tong Yao;Xiong Wan;Huang He Zhou;Zheng Jie;Li Ke;Man Heng Ye;Hu Ya Zhuo;Han Zhi Tao;Zhang Hong Hong;Wei Na;Wang Jian Zhi;Liu Dan;Lu Youming;Zhu Ling Qiang |
| 13 | Activation of MT2 receptor ameliorates dendritic abnormalities in Alzheimer's disease via C/EBP alpha/miR-125b pathway | 期刊论文 | Tang Hui;Ma Mei;Wu Ying;Deng Man Fei;Hu Fan;Almansoub Hasan a m m;Huang He Zhou;Wang Ding Qi;Zhou Lan Ting;Wei Na;Man Hengye;Lu Youming;Liu Dan;Zhu Ling Qiang |
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