面向生物威胁快速反应的大数据分析关键技术

U1435222
2014
F0213.生物信息计算与数字健康
伯晓晨
联合基金项目
研究员
中国人民解放军军事科学院军事医学研究院
480万元
生物威胁;数据挖掘;高性能计算;大数据
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Lnc2Catlas: an atlas of long noncoding RNAs associated with risk of cancers 期刊论文 Chao ren;Gaole An;Chenghui Zhao;Zhangyi Ouyang;Xiaochen Bo;Wenjie Shu
2 paraGSEA: a scalable approach for large-scale gene expression profiling 期刊论文 Peng Shaoliang;Yang Shunyun;Bo Xiaochen;Li Fei
3 Intra-host dynamics of Ebola virus during 2014 期刊论文 ming ni;Chen Chen;Jun Qian;Hai-Xia Xiao;Sheng-Qi Wang;George F. Gao;Xiao-Chen Bo;Di Liu
4 The landscape of the A-to-I RNA editome from 462 human genomes 期刊论文 Ouyang Zhangyi;Ren Chao;Liu Feng;An Gaole;Bo Xiaochen;Shu Wenjie
5 An integrative analysis of TFBS-clustered regions reveals new transcriptional regulation models on the accessible chromatin landscape. 期刊论文 Chen Hebing; Li Hao; Liu Feng; Zheng Xiaofei; Wang Shengqi; Bo Xiaochen; Shu Wenjie
6 A survey and evaluation of Web-based tools/databases for variant analysis of TCGA data 期刊论文 Zhuo Zhang;Hao Li;Shuai Jiang;Ruijiang Li;Wanying Li;Hebing Chen;Xiaochen Bo
7 Exploring the associations of host genes for viral infection revealed by genome-wide RNAi and virus-host protein interactions. 期刊论文 Xie Dafei;Han Lu;Luo Yifu;Liu Yang;He Song;Bai Hui;Wang Shengqi;Bo Xiaochen
8 B-MIC: An Ultrafast Three-Level Parallel Sequence Aligner Using MIC 期刊论文 Cui Yingbo;Liao Xiangke;Zhu Xiaoqian;Wang Bingqiang;Peng Shaoliang
9 Functional annotation of HOT regions in the human genome: implications for human disease and cancer. 期刊论文 Li Hao;Chen Hebing;Liu Feng;Ren Chao;Wang Shengqi;Bo Xiaochen;Shu Wenjie
10 A Hybrid Parallel Strategy Based on String Graph Theory to Improve De Novo DNA Assembly on the TianHe-2 Supercomputer 期刊论文 Zhang Feng;Liao Xiangke;Peng Shaoliang;Cui Yingbo;Wang Bingqiang;Zhu Xiaoqian;Liu Jie
11 Human enterovirus 71 protein interaction network prompts antiviral drug repositioning 期刊论文 Han Lu;Li Kang;Jin Chaozhi;Wang Jian;Li Qingjun;Zhang Qiling;Cheng Qiyue;Yang Jing;Bo Xiaochen;Wang Shengqi
12 Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery. 期刊论文 Jia Zhilong; Liu Ying; Guan Naiyang; Bo Xiaochen; Luo Zhigang; Barnes Michael R
13 Deep learning-based transcriptome data classification for drug-target interaction prediction 期刊论文 Lingwei Xie;Song He;Xinyu Song;Xiaochen Bo;Zhongnan Zhang
14 Discovery of novel therapeutic properties of drugs from transcriptional responses based on multi-label classification 期刊论文 Xie Lingwei;He Song;Wen Yuqi;Bo Xiaochen;Zhang Zhongnan
15 Influence of the Biliary System on Biliary Bacteria Revealed by Bacterial Communities of the Human Biliary and Upper Digestive Tracts. 期刊论文 Ye Fuqiang;Shen Hongzhang;Li Zhen;Meng Fei;Li Lei;Yang Jianfeng;Chen Ying;Bo Xiaochen;Zhang Xiaofeng;Ni Ming
16 Bioinformatics applications on Apache Spark 期刊论文 Runxin Guo;Yi Zhao;Quan Zou;Xiaodong Fang;Shaoliang Peng
17 3DSNP: a database for linking human noncoding SNPs to their three-dimensional interacting genes. 期刊论文 Lu Yiming;Quan Cheng;Chen Hebing;Bo Xiaochen;Zhang Chenggang
18 BiRen: predicting enhancers with a deep-learning-based model using the DNA sequence alone 期刊论文 Yang Bite;Liu Feng;Ren Chao;Ouyang Zhangyi;Xie Ziwei;Bo Xiaochen;Shu Wenjie
19 Parallel algorithms for large-scale biological sequence alignment on Xeon-Phi based clusters 期刊论文 Lan Haidong;Chan Yuandong;Xu Kai;Schmidt Bertil;Peng Shaoliang;Liu Weiguo
20 ICM: a web server for integrated clustering of multi-dimensional biomedical data. 期刊论文 He Song;He Haochen;Xu Wenjian;Huang Xin;Jiang Shuai;Li Fei;He Fuchu;Bo Xiaochen
21 An R Package for Characterizing and Comparing of Annotated Biological Networks 期刊论文 Yang Cao;Wenjian Xu;Xiaochen Bo;Fei Li
22 The relationships among host transcriptional responses reveal distinct signatures underlying viral infection-disease associations. 期刊论文 Han Lu;He Haochen;Qu Xinyan;Liu Yang;He Song;Zheng Xiaofei;He Fuchu;Bai Hui;Bo Xiaochen
23 De novo identification of replication-timing domains in the human genome by deep learning. 期刊论文 Liu Feng;Ren Chao;Li Hao;Zhou Pingkun;Bo Xiaochen;Shu Wenjie
24 Functional annotation of structural ncRNAs within enhancer RNAs in the human genome: implications for human disease 期刊论文 Ren Chao;Liu Feng;Ouyang Zhangyi;An Gaole;Zhao Chenghui;Shuai Jun;Cai Shuhong;Bo Xiaochen;Shu Wenjie
25 Accurate identification of RNA editing sites from primitive sequence with deep neural networks 期刊论文 Ouyang Zhangyi;Liu Feng;Zhao Chenghui;Ren Chao;An Gaole;Mei Chuan;Bo Xiaochen;Shu Wenjie
26 Efficient computation of motif discovery on Intel Many Integrated Core (MIC) Architecture 期刊论文 Peng Shaoliang;Cheng Minxia;Huang Kaiwen;Cui YingBo;Zhang Zhiqiang;Guo Runxin;Zhang Xiaoyu;Yang Shunyun;Liao Xiangke;Lu Yutong;Zou Quan;Shi Benyun
27 Network fingerprint: a knowledge-based characterization of biomedical networks. 期刊论文 Cui Xiuliang;He Haochen;He Fuchu;Wang Shengqi;Li Fei;Bo Xiaochen
28 Metagenomic sequencing of bile from gallstone patients to identify different microbial community patterns and novel biliary bacteria. 期刊论文 Shen Hongzhang;Ye Fuqiang;Xie Lu;Yang Jianfeng;Li Zhen;Xu Peisong;Meng Fei;Li Lei;Chen Ying;Bo Xiaochen;Ni Ming;Zhang Xiaofeng
29 Exploring spatially adjacent TFBS-clustered regions with Hi-C data 期刊论文 Hebing Chen;Shuai Jiang;Zhuo Zhang;Hao Li;Yiming Lu;Xiaochen Bo
30 PEDLA: predicting enhancers with a deep learning-based algorithmic framework. 期刊论文 Liu Feng;Li Hao;Ren Chao;Bo Xiaochen;Shu Wenjie
31 iFORM: Incorporating Find Occurrence of Regulatory Motifs. 期刊论文 Ren Chao;Chen Hebing;Yang Bite;Liu Feng;Ouyang Zhangyi;Bo Xiaochen;Shu Wenjie
32 Direct next-generation sequencing of virus-human mixed samples without pretreatment is favorable to recover virus genome. 期刊论文 Li Dingchen;Li Zongwei;Zhou Zhe;Li Zhen;Qu Xinyan;Xu Peisong;Zhou Pingkun;Bo Xiaochen;Ni Ming
33 Genome-wide identification and characterisation of HOT regions in the human genome. 期刊论文 Li Hao;Liu Feng;Ren Chao;Bo Xiaochen;Shu Wenjie
34 NFPscanner: a webtool for knowledge-based deciphering of biomedical networks 期刊论文 Xu Wenjian;Cao Yang;Xie Ziwei;He Haochen;He Song;Hong Hao;Bo Xiaochen;Li Fei
35 EHFPI: a database and analysis resource of essential host factors for pathogenic infection. 期刊论文 Liu Yang;Xie Dafei;Han Lu;Bai Hui;Li Fei;Wang Shengqi;Bo Xiaochen
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