AMPK对内源性H2S的调控及fraxinellone治疗炎性肠病的机制研究

81373466
2013
H3508.消化与呼吸系统药物药理
吴雪丰
面上项目
副教授
南京大学
80万元
AMPK;炎性肠病;fraxinellone;H2S
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CUG-binding protein 1 regulates HSC activation and liver fibrogenesis 期刊论文 X. Wu Y. Ma;F. Shao Y. Tan;T. Tan L. Gu;Y. Zhou B. Sun Y. Sun;X. Wu Q. Xu
2 黄柏内酯在制备治疗肺纤维化、慢性肺炎、慢性呼吸道疾病药物中的应用及其药物 专利 徐强;吴雪丰;孙洋;等
3 Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88 期刊论文 Shao Fenli;Tan Tao;Tan Yang;Sun Yang;Wu Xingxin;Xu Qiang
4 Herpetol ameliorates allergic contact dermatitis through regulating T-lymphocytes 期刊论文 Li Xiang;Wang Xingqi;Jiang Hezhong;Zhang Guohui;Tan Rui;Sun Yang;Wu Xuefeng;Tan Renxiang;Xu Qiang
5 The antioxidant Procyanidin reduces reactive Oxygen species signaling in Macrophages and ameliorates experimental colitis in Mice. 期刊论文 Lu Chen Qian You Liang Hu;Jian Gao Qianqian Meng Wentao Liu;Xuefeng Wu;Qiang Xu
6 Obaculactone exerts a novel ameliorating effect on contact dermatitis through regulating T lymphocyte 期刊论文 X. Wang Y. Zhou;S. He Z. Ouyang;L. Feng Y. Shen;X. Wu;Y. Sun Q. Xu
7 A natural compound jaceosidin ameliorates endoplasmic reticulum stress and insulin resistance via upregulation of SERCA2b 期刊论文 Ouyang Zijun;Li Wanshuai;Meng Qianqian;Zhang Qi;Wang Xingqi;Elgehama Ahmed;Wu Xudong;Shen Yan;Sun Yang;Wu Xuefeng;Xu Qiang
8 Activation of Adenosine Monophosphate- activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain 期刊论文 Song Huayuan;Han Yuan;Pan Cailong;Deng Xueting;Dai Wenling;Hu Liang;Jiang Chunyi;Yang Yanjing;Cheng Zhixiang;Li Fei;Zhang Guangqin;Wu Xuefeng;Liu Wentao
9 Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases 期刊论文 Ouyang Zijun;Wang Xingqi;Meng Qianqian;Feng Lili;Sun Yang;Wu Xuefeng;Xu Qiang
10 Decrease of functional activated T and B cells and treatment ofglomerulonephitis in lupus-prone mice using a natural flavonoid astilbin. 期刊论文 Lele Guo Wen Liu Tingting Lu Wenjie Guo;Jian Gao Qiong Luo;Xuefeng Wu;Yang Sun Xudong Wu Yan Shen Qiang Xu
11 Suppression of NF-kappa B signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone 期刊论文 Wu Xue-Feng;Ouyang Zi-Jun;Feng Li-Li;Chen Gong;Guo Wen-Jie;Shen Yan;Wu Xu-Dong;Sun Yang;Xu Qiang
12 Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice 期刊论文 Wang Xingqi;Ouyang Zijun;You Qian;He Shuai;Meng Qianqian;Hu Chunhui;Wu Xudong;Shen Yan;Sun Yang;Wu Xuefeng;Xu Qiang
13 Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes 期刊论文 Wang Xingqi;Hu Chunhui;Wu Xingxin;Wang Shiyu;Zhang Aihua;Chen Wei;Shen Yan;Tan Renxiang;Wu Xuefeng;Sun Yang;Xu Qiang
14 Targeting the PDGF-B/PDGFR-beta Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-betabeta Signaling and Attenuate Liver Fibrosis 期刊论文 X. Wang X. Wu;A. Zhang S. Wang;C. Hu W. Chen;Y. Shen R. Tan;Y. Sun Q. Xu
15 EGFR inhibitor-driven endoplasmic reticulum stress-mediated injury on intestinal epithelial cells 期刊论文 Hong Shaocheng;Gu Yanhong;Gao Zhenzhen;Guo Lele;Guo Wenjie;Wu Xudong;Shen Yan;Sun Yang;Wu Xuefeng;Xu Qiang
16 黄柏内酯在制备治疗肺纤维化、慢性肺炎、慢性呼吸道疾病药物中的应用及其药物 专利 徐强;吴雪丰;孙洋;等
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