折叠酶DsbA、DsbC、PDI在活细胞内和天然底物蛋白相互作用的分子机制

31100559
2011
C0505.蛋白质、多肽与酶生物化学
付新苗
青年科学基金项目
研究员
北京大学
25万元
非天然氨基酸;DsbA;折叠酶;PDI;二硫键
2012-01-01到2014-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Differential degradation for small heat shock proteins IbpA and IbpB is synchronized in Escherichia coli: Implications for their functional cooperation in substrate refolding 期刊论文 Shi, Xiaodong|Yan, Linxuan|Zhang, Hanlin|Sun, Kai|Chang, Zengyi|Fu, Xinmiao|
2 DegP primarily functions as a protease for the biogenesis of beta-barrel outer membrane proteins in the Gram-negative bacterium Escherichia coli 期刊论文 Ge, Xi|Wang, Rui|Ma, Jing|Liu, Yang|Ezemaduka, Anastasia N.|Chen, Peng R.|Fu, Xinmiao|Chang, Zengyi|
3 Chaperone-dependent mechanisms for acid resistance in enteric bacteria 期刊论文 Hong, Weizhe|Wu, Ye E.|Fu, Xinmiao|Chang, Zengyi|
4 PDIp is a major intracellular oestrogen-storage protein that modulates tissue levels of oestrogen in the pancreas 期刊论文 Fu, Xinmiao|Wang, Pan|Fukui, Masayuki|Long, Cheng|Yin, Linxiang|Choi, Hye Joung|Zhu, Bao Ting|
5 <strong>In vivo substrate diversity and preference of small heat shock protein IbpB as revealed by using a genetically incorporated photo-crosslinker</strong> 期刊论文 Fu X|Shi X|Yan L|Zhang H|Chang Z|
6 Chaperone-dependent mechanisms for acid resistance in enteric bacteria 期刊论文 付新苗|
7 Identification of FkpA as a Key Quality Control Factor for the Biogenesis of Outer Membrane Proteins under Heat Shock Conditions 期刊论文 Ge, Xi|Lyu, Zhi-Xin|Liu, Yang|Wang, Rui|Zhao, Xin Sheng|Fu, Xinmiao|Chang, Zengyi|
8 <strong>In vivo substrate diversity and preference of small heat shock protein IbpB as revealed by using a genetically incorporated photo-crosslinker</strong> 期刊论文 付新苗|
9 Chaperone function and mechanism of small heat-shock proteins 期刊论文 Fu, Xinmiao|
10 PDIp is a major intracellular oestrogen-storage protein that modulates tissue levels of oestrogen in the pancreas 期刊论文 付新苗|
11 Small Heat Shock Protein IbpB Acts as a Robust Chaperone in Living Cells by Hierarchically Activating Its Multi-type Substrate-binding Residues 期刊论文 Fu, Xinmiao|Shi, Xiaodong|Yin, Linxiang|Liu, Jiafeng|Joo, Keehyoung|Lee, Jooyoung|Chang, Zengyi|
12 Small Heat Shock Protein IbpB Acts as a Robust Chaperone in Living Cells by Hierarchically Activating Its Multi-type Substrate-binding Residues 期刊论文 付新苗|
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