hnRNPA1调控肝脏甘油三酯代谢的机制及其作为非酒精性脂肪肝药物靶标的研究

81673487
2016
H3507.代谢性疾病药物药理
吴旭东
面上项目
教授
南京大学
60万元
A1;甘油三酯代谢;mRNA结合调控;非酒精性脂肪肝;hnRNP
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Fatty liver diseases, mechanisms, and potential therapeutic plant medicines 期刊论文 Zhu Jia-Zhen;Yi Hong-Wei;Huang Wei;Pang Tao;Zhou Hui-Ping;Wu Xu-Dong
2 5, 7, 2 ', 4 ', 5 '-Pentamethoxyflavanone regulates M1/M2 macrophage phenotype and protects the septic mice 期刊论文 Feng Li Li;Xu Li Sha;Guo Meng Meng;Huang Wei;Zhu Jia Zhen;Kong Ling Dong;Wu Xu Dong;Xu Qiang
3 南京市第十二届自然科学优秀学术论文奖 奖励 吴兴新;吴旭东;马玉香;邵粉丽
4 黄柏内酯在制备治疗肺纤维化、慢性肺炎、慢性呼吸道疾病药物中的应用及其药物 专利 徐强;吴雪丰;孙洋;王兴启;沈燕;吴旭东;罗琼;金彪
5 一种治疗类风湿关节炎的联用药物 专利 徐强;吴旭东;高晢;吴雪丰
6 A novel combination of astilbin and low-dose methotrexate respectively targeting A2AAR and its ligand adenosine for the treatment of collagen-induced arthritis. 期刊论文 Ma Yuxiang;Gao Zhe;Xu Fang;Liu Li;Luo Qiong;Shen Yan;Wu Xuefeng;Wu Xingxin;Sun Yang;Wu Xudong;Xu Qiang
7 Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis. 期刊论文 Xu Fang;Ma Yuxiang;Huang Wei;Gao Jian;Guo Mengmeng;Li Jianxin;Kong Lingdong;Liang Guang;Du Ronghui;Xu Qiang;Wu Xudong
8 (+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway 期刊论文 Zhang Xiong;Xu Fang;Liu Li;Feng Lili;Wu Xuefeng;Shen Yan;Sun Yang;Wu Xudong;Xu Qiang
9 cis-Khellactone Inhibited the Proinflammatory Macrophages via Promoting Autophagy to Ameliorate Imiquimod-Induced Psoriasis 期刊论文 Feng Lili;Song Pingping;Xu Fang;Xu Lisha;Shao Fenli;Guo Mengmeng;Huang Wei;Kong Lingdong;Wu Xudong;Xu Qiang
10 Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH 期刊论文 Fang Xu;Mengmeng Guo;Wei Huang;Lili Feng;Jiazhen Zhu;Kangkang Luo;Jian Gao;Bingfeng Zheng;Ling-Dong Kong;Tao Pang;Xudong Wu;Qiang Xu
11 Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement. 期刊论文 Zhou Hang;Feng Lili;Xu Fang;Sun Yi;Ma Yuxiang;Zhang Xiong;Liu Hailiang;Xu Ge;Wu Xuefeng;Shen Yan;Sun Yang;Wu Xudong;Xu Qiang
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