口服靶向纳米粒子介导CD98沉默提高结肠癌化疗敏感性及其分子机制研究

81571807
2015
H2808.纳米医学
肖波
面上项目
研究员
西南大学
57万元
结肠癌;化疗敏感性;口服;靶向纳米粒子;CD98小干扰RNA
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Effects of tripolyphosphate on cellular uptake and RNA interference efficiency of chitosan-based nanoparticles in Raw 264.7 macrophages 期刊论文 Xiao Bo;Ma Panpan;Ma Lijun;Chen Qiubing;Si Xiaoying;Walter Lewins;Merlin Didier
2 Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis 期刊论文 Xiao Bo;Xu Zhigang;Viennois Emilie;Zhang Yuchen;Zhang Zhan;Zhang Mingzhen;Han Moon;Kang Yuejun;Merlin Didier
3 Oral Administration of Hydrogel-Embedding Silk Sericin Alleviates Ulcerative Colitis through Wound Healing, Anti-Inflammation, and Anti-Oxidation 期刊论文 Ma Ya;Tong Xiaoling;Huang Yamei;Zhou Xin;Yang Chunhua;Chen Jiucun;Dai Fangyin;Xiao Bo
4 Facile fabrication of bowl-shaped microparticles for oral curcumin delivery to ulcerative colitis tissue 期刊论文 Chen Qiubing;Gou Shuangquan;Huang Yamei;Zhou Xin;Li Qian;Han Moon Kwon;Kang Yuejun;Xiao Bo
5 iRGD-functionalized PEGylated nanoparticles for enhanced colon tumor accumulation and targeted drug delivery 期刊论文 Ma Lijun;Chen Qiubing;Ma Panpan;Han Moon Kwon;Xu Zhigang;Kang Yuejun;Xiao Bo;Merlin Didier
6 Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy 期刊论文 Xiao Bo;Si Xiaoying;Han Moon Kwon;Viennois Emilie;Zhang Mingzhen;Merlin Didier
7 Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation 期刊论文 Xiao Bo;Zhang Zhan;Viennois Emilie;Kang Yuejun;Zhang Mingzhen;Hang Moon Kwon;Chen Jiucun;Merlin Didier
8 Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer 期刊论文 Xiao Bo;Viennois Emilie;Chen Qiubing;Wang Lixin;Han Moon Kwon;Zhang Yuchen;Zhang Zhan;Kang Yuejun;Wan Ying;Merlin Didier
9 Oral delivery of curcumin via porous polymeric nanoparticles for effective ulcerative colitis therapy 期刊论文 Chen Qiubing;Si Xiaoying;Ma Lijun;Ma Panpan;Hou Meili;Bai Shuang;Wu Xiaoshuai;Wan Ying;Xiao Bo;Merlin Didier
10 Chondroitin sulfate-functionalized polymeric nanoparticles for colon cancer-targeted chemotherapy 期刊论文 Zu Menghang;Ma Lijun;Zhang Xueqing;Xie Dengchao;Kang Yuejun;Xiao Bo
11 Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis 期刊论文 Gou Shuangquan;Huang Yamei;Wan Ying;Ma Ya;Zhou Xin;Tong Xiaoling;Huang Jin;Kang Yuejun;Pan Guoqing;Dai Fangyin;Xiao Bo
12 Recent advances in orally administered cell-specific nanotherapeutics for inflammatory bowel disease 期刊论文 Si Xiaoying;Merlin Didier;Xiao Bo
13 Mucus-penetrating polymeric nanoparticles for oral delivery of curcumin to inflamed colon tissue 期刊论文 Zhou Xin;Liu Yao;Huang Yamei;Ma Ya;Lv Jun;Xiao Bo
14 Oral Drug Delivery Systems for Ulcerative Colitis Therapy: A Comparative Study with Microparticles and Nanoparticles 期刊论文 Ma Panpan;Si Xiaoying;Chen Qiubing;Ma Lijun;Hou Meili;Xu Zhigang;Kang Yuejun;Wang Jianglin;Xiao Bo
15 一种基于丝素蛋白的可触变水凝胶的制备方法及产品和应用 专利 肖波;苟双全
16 Green Fabrication of Ovalbumin Nanoparticles as Natural Polyphenol Carriers for Ulcerative Colitis Therapy 期刊论文 Shuangquan Gou;Qiubing Chen;Yan Liu;Liang Zeng;Heliang Song;Zhigang Xu;Yuejun Kang;Changming Li;Bo Xiao
17 2018全国再生医学材料大会“青年论文奖” 奖励 肖波
18 Silk fibroin-based nanotherapeutics: application in the treatment of colonic diseases 期刊论文 Shuangquan Gou;Yamei Huang;Junsik Sung;Bo Xiao;Didier Merlin
19 Oral administration of chondroitin sulfate-functionalized nanoparticles for colonic macrophage-targeted drug delivery 期刊论文 Zhang Xueqing;Ma Ya;Ma Lijun;Zu Menghang;Song Heliang;Xiao Bo
20 一种新型载药碗状粒子的制备方法及其应用 专利 肖波;陈秋冰
21 一种载抗肿瘤药物电纺微米纤维膜及其制备方法 专利 肖波;马盼盼
22 Porous Polymeric Microparticles as an Oral Drug Platform for Effective Ulcerative Colitis Treatment 期刊论文 Zhou Xin;Chen Qiubing;Ma Ya;Huang Yamei;Gou Shuangquan;Xiao Bo
23 Oral administration of colitis tissue-accumulating porous nanoparticles for ulcerative colitis therapy 期刊论文 Chen Qiubing;Gou Shuangquan;Ma Panpan;Song Heliang;Zhou Xin;Huang Yamei;Han Moon Kwon;Wan Ying;Kang Yuejun;Xiao Bo
24 TNFα gene silencing mediated by orally targeted nanoparticles combined with interleukin-22 for synergistic combination therapy of ulcerative colitis 期刊论文 Xiao Bo;Chen Qiubing;Zhang Zhan;Wang Lixin;Kang Yuejun;Denning Timothy;Merlin Didier
25 一种溃疡性结肠炎组织靶向分子及其应用 专利 肖波;司笑莹;汪敏
26 Hyaluronic acid-functionalized polymeric nanoparticles for colon cancer-targeted combination chemotherapy 期刊论文 Xiao Bo;Han Moon Kwon;Viennois Emilie;Wang Lixin;Zhang Mingzhen;Si Xiaoying;Merlin Didier
27 Urocanic acid-modified chitosan nanoparticles can confer anti-inflammatory effect by delivering CD98 siRNA to macrophages 期刊论文 Xiao Bo;Ma Panpan;Viennois Emilie;Merlin Didier
28 Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy 期刊论文 Xiao Bo;Ma Lijun;Merlin Didier
29 Low-frequency ultrasound may improve drug penetration in colonic mucosa 期刊论文 Chen Qiubing;Xiao Bo;Merlin Didier
30 Nanotherapeutics for the treatment of inflammatory bowel disease 期刊论文 Chen Qiubing;Xiao Bo;Merlin Didier
31 一种用于巨噬细胞靶向药物递送的纳米粒子及其制备方法 专利 肖波;马莉君;汪敏
32 一种结肠肿瘤细胞主动靶向的纳米粒子及其制备方法 专利 肖波;马莉君;汪敏
33 Modulation of drug release by decoration with Pluronic F127 to improve anti-colon cancer activity of electrospun fibrous meshes 期刊论文 Ma Panpan;Gou Shuangquan;Ma Ya;Chen Qiubing;Zhu Siyuan;Chen Jiucun;Kang Yuejun;Xiao Bo
34 Facile Fabrication of Oxidation-Responsive Polymeric Nanoparticles for Effective Anticancer Drug Delivery 期刊论文 Huang Yamei;Chen Qiubing;Ma Panpan;Song Heliang;Ma Xiaoqian;Ma Ya;Zhou Xin;Gou Shuangquan;Xu Zhigang;Chen Jiucun;Xiao Bo
35 2018 Nano- Meso- and Microstructured Materials for Energy, Electronics and Biotechnology SUSTech Workshop “Best Poster Award” (“最佳海报奖”) 奖励 肖波
36 Knitted Silk Fibroin-Reinforced Bead-on-String Electrospun Fibers for Sustained Drug Delivery Against Colon Cancer 期刊论文 Ma Panpan;Gou Shuangquan;Wang Min;Chen Jiucun;Hu Wei;Xiao Bo
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