【21275119】酶催化原位生成共反应试剂增强电致化学发光的超灵敏适体传感器研究国家自然基金项目

酶催化原位生成共反应试剂增强电致化学发光的超灵敏适体传感器研究

项目批准号： 21275119

批准年份： 2012

学科分类： B0402.电分析化学

项目负责人：袁若

资助类别：面上项目

负责人职称：教授

依托单位：西南大学

资助金额： 80万元

关键词：血清疾病标志物;电致化学发光;适体传感器;原位生成共反应试剂;纳米材料

起止时间： 2013-01-01到2016-12-31

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序号	标题	类型	作者
1	Ultrasensitive simultaneous detection of four biomarkers based on hybridization chain reaction and biotin-streptavidin signal amplification strategy	期刊论文	Zhu Qiang\|Chai Yaqin\|Zhuo Ying\|Yuan Ruo\|
2	Ultrasensitive Cytosensor Based on Self-Enhanced Electrochemiluminescent Ruthenium-Silica Composite Nanoparticles for Efficient Drug Screening with Cell Apoptosis Monitoring	期刊论文	Xiong, Chengyi\|Zheng, Yingning\|Chai, Yaqin\|Yuan, Ruo\|
3	In situ electro-polymerization of nitrogen doped carbon dots and their application in an electrochemiluminescence biosensor for the detection of intracellular lead ions	期刊论文	Zheng, Yingning\|Zhuo, Ying\|Chai, Yaqin\|Yuan, Ruo\|
4	Fe3O4NPs mediated nonenzymatic electrochemical immunosensor for the total protein of Nosema bombycis detection without addition of substrate	期刊论文	Wang Qin\|Chai Yaqin\|Yuan Yali\|Yuan Ruo\|
5	Ultrasensitive Apurinic/Apyrimidinic Endonuclease 1 Immunosensing Based on Self-Enhanced Electrochemiluminescence of a Ru(II) Complex	期刊论文	Zhao Min\|Han Jing\|Xiang Yun\|Yuan Ruo\|
6	Highly Effective Protein Converting Strategy for Ultrasensitive Electrochemical Assay of Cystatin C	期刊论文	Yang Zhehan\|Zhuo, Ying\|Yuan, Ruo\|Chai Yaqin\|
7	3,4,9,10-Perylenetetracarboxylic acid/o-phenylenediamine nanomaterials as novel redox probes for electrochemical aptasensor systems based on an Fe3O4 magnetic bead as a nonenzymatic catalyst	期刊论文	Chang Yuanyuan\|Xie Shunbi\|Chai Yaqin\|Yuan Ruo\|
8	L-Cysteine induced hemin/G-quadruplex concatemers electrocatalytic amplification with Pt-Pd supported on fullerene as a nanocarrier for sensing the spore wall protein of Nosema bombycis	期刊论文	Xie Hua\|Chai Yaqin\|Yuan Yali\|Yuan Ruo\|
9	An ultrasensitive electrochemical aptasensor with autonomous assembly of hemin-G-quadruplex DNAzyme nanowires for pseudo triple-enzyme cascade electrocatalytic amplification	期刊论文	Chai Yaqin\|Yuan Ruo\|Zhuo Ying\|Gan Xxianxue\|
10	Self-Enhanced Electrochemiluminescence Nanorods of Tris(bipyridine) Ruthenium(II) Derivative and Its Sensing Application for Detection of N？Acetyl-β？D？glucosaminidase	期刊论文	Yuan Yali\|Zhuo Ying\|Chai Yaqin\|Yuan Ruo\|
11	An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host-guest interaction between ferrocene and beta-cyclodextrin	期刊论文	Zhang Jin\|Yuan Yali\|Chai Yaqin\|Yuan Ruo\|
12	Multiparameter Analysis-Based Electrochemiluminescent Assay for Simultaneous Detection of Multiple Biomarker Proteins on a Single Interface	期刊论文	Zheng, Yingning\|Xiong, Chengyi\|Chai, Yaqin\|Yuan, Ruo\|
13	Cu-Based Metal？Organic Frameworks as a Catalyst To Construct a Ratiometric Electrochemical Aptasensor for Sensitive Lipopolysaccharide Detection	期刊论文	ShenWenjun\|Zhuo Ying\|Chai Yaqin\|Yuan Ruo\|
14	In Situ Electrochemical Generation of Electrochemiluminescent Silver Naonoclusters on Target-Cycling Synchronized Rolling Circle Amplification Platform for MicroRNA Detection	期刊论文	Ma, Shaoyong\|Zhuo, Ying\|Chai, Yaqin\|Yuan, Ruo\|
15	Triple Quenching of a Novel Self-Enhanced Ru(II) Complex by Hemin/G-Quadruplex DNAzymes and Its Potential Application to Quantitative Protein Detection	期刊论文	Zhuo Ying\|Chai Yaqin\|Wang Jipeng\|Yuan Ruo\|
16	Ultrasensitive immunoassay based on a pseudobienzyme amplifying system of choline oxidase and luminol-reduced Pt@Au hybrid nanoflowers	期刊论文	Zhuo Ying\|Liao Ni\|Chai Yaqin\|Yuan Ruo\|
17	Self-enhanced electrochemiluminescence immunosensor based on nanowires obtained by a green approach.Biosens	期刊论文	Wang Haijun\|Yuan Yali\|Chai Yaqin\|Yuan Ruo\|
18	An "Off On" Electrochemiluminescent Biosensor Based on DNAzyme-Assisted Target Recycling and Rolling Circle Amplifications for Ultrasensitive Detection of microRNA	期刊论文	Zhang Pu\|Wu Xiaoyan\|Yuan Ruo\|Chai Yaqin\|
19	Dual-responses for electrochemical and electrochemiluminescent detection based on a bifunctional probe	期刊论文	Han Jing\|Zhuo Ying\|Chai Yaqin\|Yuan Ruo\|
20	Ultrasensitive Lipopolysaccharides Detection Based on Doxorubicin Conjugated N-(Aminobutyl)-N-(ethylisoluminol) as Electrochemiluminescence Indicator and Self-Assembled Tetrahedron DNA Dendrimers as Nanocarriers	期刊论文	Dong, Yongwang\|Yuan, Yali\|Chai, Yaqin\|Yuan, Ruo\|
21	Luminescence-Functionalized Metal–Organic Frameworks Based on a Ruthenium(II) Complex: A Signal Amplification Strategy for Electrogenerated Chemiluminescence Immunosensors	期刊论文	Liang Wenbin\|Yuan Yali\|Yuan Ruo\|Chai Yaqin\|
22	A ferrocene-switched electrochemiluminescence "off-on'' strategy for the sensitive detection of cardiac troponin I based on target transduction and a DNA walking machine	期刊论文	Xu Ziqi\|Dong Yongwang\|Li Jiyang\|Yuan Ruo\|
23	Highly sensitive electrochemiluminescenc assay of acetylcholinesterase activity based on dual biomarkers using Pd-Au nanowires as immobilization platform	期刊论文	Zhong Xia\|Chen Shihong\|Chai Yaqin\|Yuan Ruo\|
24	Manganese porphyrin-double stranded DNA complex guided in situ deposition of polyaniline for electrochemical thrombin detection	期刊论文	Xie Shunbi\|Chai Yaqin\|Yuan Yali\|Yuan Ruo\|
25	A highly sensitive electrochemiluminescence biosensor for the detection of organophosphate pesticides based on cyclodextrin functionalized graphitic carbon nitride and enzyme inhibition	期刊论文	Zhong, Xia\|Chai, Yaqin\|Chen, Shihong\|Yuan, Ruo\|
26	Self-Enhanced Ultrasensitive Photoelectrochemical Biosensor Based on Nanocapsule Packaging Both Donor-Acceptor-Type Photoactive Material and Its Sensitizer	期刊论文	Xiong, Cheng-Yi\|Yuan, Ya-Li\|Chai, Ya-Qin\|Yuan, Ruo\|
27	Competitive method-based electrochemiluminescent assay with protein–nucleotide conversion for ratio detection to efficiently monitor the drug resistance of cancer cells	期刊论文	Zheng Yingning\|Xiong Chengyi\|Chai Yaqin\|Yuan Ruo\|
28	Sensitive Electrochemiluminescence Immunosensor for Detection of N-Acetyl-beta-D-glucosaminidase Based on a "Light-Switch" Molecule Combined with DNA Dendrimer	期刊论文	Yuan, Yali\|Zhuo, Ying\|Chai, Yaqin\|Yuan, Ruo\|
29	Signal-off Electrochemiluminescence Biosensor Based on Phi29 DNA Polymerase Mediated Strand Displacement Amplification for MicroRNA Detection	期刊论文	Zhuo Ying\|Chai Yaqin\|Xiang Yun\|Yuan Ruo\|
30	In Situ Generation of Self-Enhanced Luminophore by β？Lactamase Catalysis for Highly Sensitive Electrochemiluminescent Aptasensor	期刊论文	Zhuo Ying\|Chai Yaqin\|Xiang Yun\|Yuan Ruo\|
31	New type of redox nanoprobe: C60-based nanomaterial and its application in electrochemical immunoassay for doping detection	期刊论文	Zhuo Ying\|Chai Yaqin\|Xiang Yun\|Yuan Ruo\|
32	Tracing Phosphate Ions Generated during Loop-Mediated Isothermal Amplification for Electrochemical Detection of Nosema bombycis Genomic DNA PTP1	期刊论文	Xie Shunbi\|Yuan Yali\|Chai Yaqin\|Yuan Ruo\|
33	A novel electrochemiluminescence aptasensor based on in situ generated proline and matrix polyamidoamine dendrimers as coreactants for signal amplication	期刊论文	Yuan Yali\|Gan Xianxue\|Chai Yaqin\|Yuan Ruo\|
34	A new hybrid signal amplification strategy for ultrasensitive electrochemical detection of DNA based on enzyme-assisted target recycling and DNA supersandwich assemblies	期刊论文	Xu Jin\|Xiang Yun\|Yuan Ruo\|Chai Yaqin\|
35	Self-Enhanced Electrochemiluminescence Nanorods of Tris(bipyridine) Ruthenium(II) Derivative and Its Sensing Application for Detection of N-Acetyl-beta-D-glucosaminidase	期刊论文	Yuan, Yali\|Zhuo, Ying\|Chai, Yaqin\|Yuan, Ruo\|
36	Target protein induced cleavage of a specific peptide for prostate-specific antigen detection with positively charged gold nanoparticles as signal enhancer	期刊论文	Zheng Yingning\|Chai Yaqin\|Yuan Yali\|Yuan Ruo\|
37	A ferrocene-switched electrochemiluminescence "off-on'' strategy for the sensitive detection of cardiac troponin I based on target transduction and a DNA walking machine	期刊论文	Xu Ziqi\|Dong Yongwang\|Li Jiyang\|Yuan Ruo\|
38	An "Off On" Electrochemiluminescent Biosensor Based on DNAzyme-Assisted Target Recycling and Rolling Circle Amplifications for Ultrasensitive Detection of microRNA	期刊论文	Zhang Pu\|Wu Xiaoyan\|Yuan Ruo\|Chai Yaqin\|
39	Sensitive Electrochemiluminescence Immunosensor for Detection of N-Acetyl-beta-D-glucosaminidase Based on a "Light-Switch" Molecule Combined with DNA Dendrimer	期刊论文	Yuan, Yali\|Zhuo, Ying\|Chai, Yaqin\|Yuan, Ruo\|

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