骨科植入材料的表面功能化构建及基础科学问题研究

U1801252
2018
王迎军
联合基金项目
教授
华南理工大学
255万元
成骨;表面构建;生物活性多肽;植入材料;抗菌多肽
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Dual detection of bioaccumulated Hg2+ based on luminescent bacteria and aggregation-induced emission 期刊论文 Letao Huang;Shiwu Li;Xia Ling;Jun Zhang;Anjun Qin;Jian Zhuang;Meng Gao;Ben Zhong Tang
2 Modulation of Conformational Transition of Polypeptides under Slightly Acidic Environment(dagger). 期刊论文 Li Jie;Zhang Jiajie;Qi Long;Guo Weisheng;Xiong Menghua
3 One-step preparation of the engineered titanium implant by rationally designed linear fusion peptides with spacer-dependent antimicrobial, anti-inflammatory and osteogenic activities. 期刊论文 Xin Haoqian;Chen Junjian;Li Tianjie;Hu Guansong;Fang Zhou;Zhou Haiyan;Guo Kunzhong;Wang Lin;Wang Yingjun
4 Phosphorylated Chitosan Hydrogels Inducing Osteogenic Differentiation of Osteoblasts via JNK and p38 Signaling Pathways 期刊论文 Liu Lei;Miao Yali;Shi Xuetao;Gao Huichang;Wang Yingjun
5 A promoted copper-catalysed Azide-alkyne cycloaddition (CuAAC) for broad spectrum peptide-engineered implants 期刊论文 Hu Guansong;Chen Junjian;Fan Yan;Zhou Haiyan;Guo Kunzhong;Fang Zhou;Xie Liangxu;Wang Lin;Wang Yingjun
6 On-demand storage and release of antimicrobial peptides using Pandora's box-like nanotubes gated with a bacterial infection-responsive polymer 期刊论文 Junjian Chen;Xuetao Shi;Ye Zhu;Yunhua Chen;Meng Gao;Huichang Gao;Lei Liu;Lin Wang;Chuanbin Mao;Yingjun Wang
7 Mitochondria-anchoring and AIE-active photosensitizer for self-monitored cholangiocarcinoma therapy 期刊论文 Tao Zhou;Jianfang Zhu;Dan Shang;Chuxing Chai;Youzhen Li;Haiying Sun;Yongqin Li;Meng Gao;Min Li
8 一种新型点击化学体系构建功能化骨植入材料表面的方法及构建的功能化骨植入材料 专利 王迎军;胡冠松;王琳;陈军建;范燕;郑志雯;李天杰;郝丽静
9 一种融合多肽及其制备方法与应用 专利 王迎军;胡冠松;王琳;陈军建;范燕;郑志雯;李天杰;郝丽静
10 pH敏感的聚甲基丙烯酸酯类高分子化合物及其应用 专利 王迎军;熊梦华;黄雪连;黄炳川;黄良琪
11 一种基于介孔二氧化硅的表面功能化钛基植入体及其制备方法与应用 专利 王迎军;董洎瑀;王琳;邵丹
12 Calcium alendronate-coated composite scaffolds promote osteogenesis of ADSCs via integrin and FAK/ERK signalling pathways 期刊论文 Liu Lei;Gao Xianling;Li Xiaoyu;Zhu Guanglin;Li Nanying;Shi Xuetao;Wang Yingjun
13 Fluorescent In Situ 3D Visualization of Dynamic Corrosion Processes of Magnesium Alloys 期刊论文 Xubo Tong;Dong Bian;Lijing Hao;Lin Wang;Limin Ma;Meng Gao;Yingjun Wang
14 Mechanistic insights into the adsorption and bioactivity of fibronectin on surfaces with varying chemistries by a combination of experimental strategies and molecular simulations 期刊论文 Lijing Hao;Tianjie Li;Lin Wang;Xuetao Shi;Yan Fan;Chang Du;Yingjun Wang
15 Improved Small Extracellular Vesicle Secretion of Rat Adipose-Derived Stem Cells by Microgrooved Substrates through Upregulation of the ESCRT-III-Associated Protein Alix 期刊论文 Yurong Ji;Weiju Han;Xiaoling Fu;Jing Li;Qi Wu;Yingjun Wang
16 Conductive and antimicrobial macroporous nanocomposite hydrogels generated from air-in-water Pickering emulsions for neural stem cell differentiation and skin wound healing 期刊论文 Xu Mingjian;Li Qingtao;Fang Zhou;Jin Min;Zeng Qing;Huang Guozhi;Jia Yong-Guang;Wang Lin;Chen Yunhua
17 3D-printed bioactive ceramic scaffolds with biomimetic micro/nano-HAp surfaces mediated cell fate and promoted bone augmentation of the bone-implant interface in vivo 期刊论文 Xiao Liu;Yali Miao;Haifeng Liang;Jingjing Diao;Lijing Hao;Zhifeng Shi;NaRu Zhao;Yingjun Wang
18 AIE-based cancer theranostics. 期刊论文 Meng Gao;Ben Zhong Tang
19 Visualizing phase transition of upper critical solution temperature (UCST) polymers with AIE 期刊论文 Yong-Guang Jia;Kai-Feng Chen;Meng Gao;Sa Liu;Jin Wang;Xiaohui Chen;Lin Wang;Yunhua Chen;Wenjing Song;Huatang Zhang;Li Ren;Xiao-Xia Zhu;Ben Zhong Tang
20 Controlling the adsorption of osteopontin for mediating cell behaviour by using self-assembled monolayers with varying surface chemistry 期刊论文 Zhuoying Chen;Yan Fan;Lin Wang;Zhengqi Bian;Lijing Hao
21 一种融合多肽修饰的钛基植入体及其制备 方法 专利 王迎军;辛浩千;王琳;陈军建;范燕;胡冠松;方舟;郝丽静
22 一种纳米/微米多级孔结构的生物活性陶瓷 支架及其制备方法 专利 王迎军;刁静静;赵娜如
23 A Water-Stable and Red-Emissive Radical Cation for Mutp53 Cancer Therapy 期刊论文 Zikai Zhou;Jieying Qian;Kai Liu;Yunjiao Zhang;Meng Gao;Ben ZhongTang
24 Upper Critical Solution Temperature Polyvalent Scaffolds Aggregate and Exterminate Bacteria 期刊论文 Chen Kaifeng;Zhang Yiqing;Lin Jiawei;Chen Yun-You;Lin Caihong;Gao meng;Chen Yunhua;Liu sa;Wang Lin;Cui Zhongkai;Jia Yongguang
25 Macroporous Adhesive Nano-Enabled Hydrogels Generated from Air-in-Water Emulsions 期刊论文 Manshan Xie;Zhiwen Zheng;Shiheng Pu;Yong-Guang Jia;Lin Wang;Yunhua Chen
26 Wet-adhesive, haemostatic and antimicrobial bilayered composite nanosheets for sealing and healing soft-tissue bleeding wounds 期刊论文 Xuan Chengkai;Hao Lijin;Liu Xuemin;Zhu Ye;Yang Huishang;Ren Yipeng;Wang Lin;Fujie Toshinori;Wu Hongkai;Chen Yunhua;Shi Xuetao;Mao Chuanbin
27 Constructing a Sr2+-Substituted Surface Hydroxyapatite Hexagon-Like Microarray on 3D-Plotted Hydroxyapatite Scaffold to Regulate Osteogenic Differentiation 期刊论文 Wei Yingqi;Gao Huichang;Hao Lijing;Shi Xuetao;Wang Yingjun
28 Promotion of the immunomodulatory properties and osteogenic differentiation of adipose-derived mesenchymal stem cells in vitro by lentivirus-mediated mir-146a sponge expression 期刊论文 Wan Shuangyan;Wu Qi;Ji Yurong;Fu Xiaoling;Wang Yingjun
29 Mechanistic Insights and Rational Design of a Versatile Surface with Cells/Bacteria Recognition Capability via Orientated Fusion Peptides 期刊论文 Lin Wang;Junjian Chen;Xiangze Zeng;Peter Pak-Hang Cheung;Xiaoyan Zheng;Liangxu Xie;Xuetao Shi;Li Ren;Xuhui Huang;Yingjun Wang
30 一种能够调控间充质干细胞旁分泌的仿生骨单位结构及其制备方法 专利 王迎军;李梦杰;付晓玲
31 一种抗菌金纳米簇及其制备方法与应用 专利 王迎军;陈军建;王琳;辛浩千
32 一种大尺寸个性化生物活性陶瓷植入体的制备方法 专利 王迎军;刁静静;赵娜如
33 一种在钙磷硅陶瓷表面原位构建羟基磷灰石微纳米中空管的方法 专利 王迎军;刘骁;赵娜如
34 一种多功能型仿生HA颗粒负载姜黄素前药 微纳米复合材料及其制备方法和应用 专利 王迎军;杜昶;徐东;万宇欣
35 Black phosphorus nanosheets-enabled DNA hydrogel integrating 3D-printed scaffold for promoting vascularized bone regeneration 期刊论文 Yali Miao;Yunhua Chen;Jinshui Luo;Xiao Liu;Qian Yang;Xuetao Shi;Yingjun Wang
36 Photo-triggered Zn2+ release for the regulation of zinc enzymes. 期刊论文 Zhang Minjie;Jia Yongguang;Gao Meng;Ren Li;Tang Benzhong
37 AIE-Based Theranostic Probe for Sequential Imaging and Killing of Bacteria and Cancer Cells 期刊论文 Xiaohui Chen;Letao Huang;Yongguang Jia;Rong Hu;Meng Gao;Li Ren;Ben Zhong Tang
38 Bilayered nanosheets used for complex topography wound anti-infection 期刊论文 Xuan Chengkai;Liu Xuemin;Lai Chen;Shi Xuetao
39 一种具有细胞器依次成像和双色成像功能的光激活探针及其应用 专利 王迎军;张子聪;高蒙
40 一种具高结晶度及长径比双膦酸盐晶体及其制备方法 专利 王迎军;张惠琳;朱光林;施雪涛
41 High-throughput screening and rational design of biofunctionalized surfaces with optimized biocompatibility and antimicrobial activity 期刊论文 Zhou Fang;Junjian Chen;Ye Zhu;Guansong Hu;Haoqian Xin;Kunzhong Guo;Qingtao Li;Liangxu Xie;Lin Wang;Xuetao Shi;Yingjun Wang;Chuanbin Mao
42 一种具有多细胞器依次成像和光动力治疗功能的荧光诊疗探针及其应用 专利 王迎军;潘文萍;高蒙
43 一种pH响应型原位控释钛基植入体及其制备方法与应用 专利 王迎军;陈军建;王琳
44 2019年度广东省科学技术突出贡献奖 奖励 王迎军
45 A Self-Reporting Fluorescent Salicylaldehyde-Chlorambucil Conjugate as a Type-II ICD Inducer for Cancer Vaccines 期刊论文 Minjie Zhang;Xin Jin;Meng Gao;Yunjiao Zhang;Ben Zhong Tang
46 Fusion peptide engineered “statically-versatile” titanium implant simultaneously enhancing anti-infection, vascularization and osseointegration 期刊论文 Junjian Chen;Guansong Hu;Tianjie Li;Yunhua Chen;Meng Gao;Qingtao Li;Lijing Hao;Yongguang Jia;Lin Wang;Yingjun Wang
47 Photoactivatable dihydroalkaloids for cancer cell imaging and chemotherapy with high spatiotemporal resolution. 期刊论文 Xia Ling;Letao Huang;Youzhen Li;Qing Wan;Zhiming Wang;Anjun Qin;Meng Gao;Ben Zhong Tang
48 Polymyxin B engineered polystyrene-divinylbenzene microspheres for the adsorption of bilirubin and endotoxin. 期刊论文 Yang Kangle;Peng Yaotian;Wang Lin;Ren Li
49 A transistor-like pH-sensitive nanodetergent for selective cancer therapy 期刊论文 Mingdong Liu;Liangqi Huang;Weinan Zhang;Xiaochuan Wang;Yuanyuan Geng;Yuhao Zhang;Li Wang;Wenbin Zhang;Yun-Jiao Zhang;Shiyan Xiao;Yan Bao;Menghua Xiong;Jun Wang
50 Red-to-NIR emissive radical cations derived from simple pyrroles. 期刊论文 Zhang Lihua;Zhu Wenchao;Zhou Zikai;Liu Kai;Gao Meng;Tang Benzhong
51 Engineering natural matrices with black phosphorus nanosheets to generate multi-functional therapeutic nanocomposite hydrogels 期刊论文 Yali Miao;Xuetao Shi;Qingtao Li;Lijing Hao;Lei Liu;Xiao Liu;Yunhua Chen;Yingjun Wang
52 一种具有响应效应的多功能植入体及其制备方法与应用 专利 王迎军;陈军建;王琳
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