VEGF-Src 信号阻断预防激素性骨坏死破坏性骨修复的基础研究

81171771
2011
H0611.运动系统疾病研究新技术与新方法
秦岭
面上项目
教授
中国科学院深圳先进技术研究院
60万元
软骨下塌陷;激素性骨坏死;血管内皮生长因子;破坏性骨修复;Src
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Blockage of Src by Specific siRNA as a Novel Therapeutic Strategy to Prevent Destructive Repair in Steroid-Associated Osteonecrosis in Rabbits 期刊论文 Wang, Xin-luan|Wang, Xin-luan|Qin, Ling|Qin, Ling|
2 Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in rabbit 会议论文
3 Review of various treatment options and potential therapies for osteonecrosis of the femoral head 期刊论文 Ling Qin|Ling Qin|Xinluan Wang|Xinluan Wang|
4 Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity– an in vitro mechanism study for preventing destructive repair of osteonecrosis 期刊论文 Xinluan Wang|Xinluan Wang|Ling Qin|Ling Qin|
5 Systemic drug delivery systems for bone tissue regeneration- a mini review. 期刊论文 Zhijun, Yang|Zhijun, Yang|Ling, Qin|Ling, Qin|
6 Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in rabbit 会议论文
7 Blockage of src by specific sirna as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis 会议论文
8 Src siRNA prevents corticosteroid-associated osteoporosis in a rabbit model 期刊论文 Hui-Juan Cao|Shi-Hui Chen|Le Huang|Ling Qin|
9 Systemic drug delivery systems for bone tissue regeneration- a mini review. 期刊论文 Zhijun, Yang|Zhijun, Yang|Ling, Qin|Ling, Qin|
10 Multiple biomedical imaging modalities for systemic evaluations of Src siRNA developed for prevention of destructive repair of steroid associated osteonecrosis in rabbits 会议论文
11 Blockage of Src by Specific siRNA as a Novel Therapeutic Strategy to Prevent Destructive Repair in Steroid-Associated Osteonecrosis in Rabbits 期刊论文 Wang, Xin-luan|Wang, Xin-luan|Qin, Ling|Qin, Ling|
12 Puerarin promotes osteogenesis and inhibits adipogenesis in vitro 期刊论文 Cheng, Wenxiang|Cao, Huijuan|Zhang, Peng|Qin, Ling|
13 Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity– an in vitro mechanism study for preventing destructive repair of osteonecrosis 期刊论文 Xinluan Wang|Xinluan Wang|Ling Qin|Ling Qin|
14 Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis 会议论文
15 Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis 会议论文
16 VEGF－Src signaling is essential for vascular endothelial permeability and osteoclasts activity 会议论文
17 VEGF-Src signaling blockade reduced both vascular permeability and osteoclastic bone absorption in vitro 会议论文
18 VEGF-Src signaling blockade reduced both vascular permeability and osteoclastic bone absorption in vitro 会议论文
19 Src siRNA维持激素性骨坏死中的骨质代谢平衡的研究 会议论文
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