【51172188】纳米相表面修饰多尺度孔隙结构骨再生支架研制国家自然基金项目

纳米相表面修饰多尺度孔隙结构骨再生支架研制

项目批准号： 51172188

批准年份： 2011

学科分类： E0210.无机非金属类生物材料

项目负责人：翁杰

资助类别：面上项目

负责人职称：教授

依托单位：西南交通大学

资助金额： 60万元

关键词：生物材料;血管化;多层次孔隙结构;骨再生支架;纳米相表面修饰

起止时间： 2012-01-01到2015-12-31

中英文摘要
结题摘要
结题报告
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序号	标题	类型	作者
1	羟基磷灰石基多孔复合支架的制备及其表征	期刊论文	许韬韬\|段可\|屈树新\|翁杰\|
2	Room-temperature attachment of PLGA microspheres to titanium surfaces for implant-based drug release	期刊论文	Tao Xie\|Tailin Guo\|Ke Duan\|Jie Weng\|
3	Heterotopic osteogenesis of spherule accumulating scaffolds with different proportions of calcium sulfate/hydroxyapatite in vivo	会议论文	Huitao Luo \|Ke Duan \|Shuxin Qu \|Jie Weng\|
4	Fabrication of Translucent Hydroxyapatite Ceramics with Different Forms by Sol-Gel Method	期刊论文	Duan Ke\|Zhang Cheng-Dong\|Qu Shu-Xin\|Weng Jie\|
5	基于 Micro-CT 不同多孔结构陶瓷支架的建模及其贯通性与液流分布分析	期刊论文	罗品风, 智伟, 张静微, 匙峰, 段可, 汪建新, 鲁雄, 翁杰*\|
6	Triclosan release from PLGA microspheres loaded porous titanium: A general design to impart biofunction to bone implants	会议论文	Ke Duan\|Lin Lan\|Xiaohong Li\|Jie Weng\|
7	Hydrothermal fabrication of nanostructured hydroxyapatite particles tailored by small organic molecules and metallic ions	会议论文
8	血管化生物活性陶瓷骨修复体构建的基础及临床研究	奖励
9	Preparation of highly interconnected porous hydroxyapatite scaffolds via sugar sphere-leaching process	会议论文
10	模板法制备羟基磷灰石纳米结构微球及其机制探讨	期刊论文	姚宁\|张成栋\|段可\|翁杰\|
11	A novel porous bioceramics scaffold by accumulating hydroxyapatite spherulites for large bone tissue engineering in vivo. II. Construct large volume of bone grafts	期刊论文	Qu S\|Li X\|Weng J\|Zhu Z\|
12	Fabrication of porous HA bioceramics with the designed micro/nano structured surfaces	会议论文	Shuxin Qu\|Shaobin Zhou\|Xiong Lu\|Jie Weng\|
13	掺铜羟基磷灰石微球的制备及表征	期刊论文	肖东琴, 姚宁, 王东薇, 任俊臣, 段可, 翁杰*\|
14	Histomorphological researches on large porous hydroxyapatite cylinder tubes with polylactic acid surface coating in different nonskeletal sites in vivo	期刊论文	Feng HZ\|Yao YM\|Li S\|Xia T\|
15	不同类型多孔结构生物材料支架制备及其性能优化	期刊论文	段可\|冯波\|李孝红\|翁杰\|
16	Fabrication of hollowhydroxyapatite particles assisted by small organic molecule and effect ofmicrostructure on protein adsorption	期刊论文	Xiao DQ, Zhou X, Li HY, Duan K, Lu X, Weng J*\|
17	Preparation of translucent hydroxyapatite in different forms by a sol-gel shaping and HIP sintering	会议论文	Jun Ye\|Jinyu Li\|Lin Li\|Jie Weng\|
18	Hydrothermal synthesis of hollow hydroxyapatite microspheres with nano-structured surface assisted by inositol hexakisphosphate	期刊论文	Ke Duan\|Xiaotong Zheng\|Xiong Lu\|Jie Weng\|
19	表面形貌可控的磷酸钙陶瓷的生物响应性研究	会议论文
20	多孔磷酸钙生物陶瓷支架调控体内异位成骨的关键因素	会议论文
21	Modulating cellular behaviors on completely dense hydroxyapatite through biomimic pits	期刊论文	Rongquan Duan\|Wei Zhi\|Yuanyuan Zheng\|Jie Weng\|
22	生物材料表面微纳结构对成骨相关细胞的影响	期刊论文	鲁雄, 冯波\|翁杰*\|冷扬\|
23	Fabrication of tissue engineering scaffolds with various porous structures and their applications in harvesting vascularized naturally bone-like grafts	会议论文
24	体内仿生培养类自体骨修复体及其承力部位骨缺失修复	会议论文
25	Biomechanical property of tissue engineered grafts constructed in vivo using porous hydroxyapatite scaffolds	会议论文	Lin Li\|Peng Huang\|Xiang Ren\|Jie Weng\|
26	Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite	期刊论文	Wenyuan Kang\|Dongqin Xiao\|Rongquan Duan\|Jie Weng\|
27	Integrating surface topography of stripe pattern on pore surface of 3-dimensional hydroxyapatiye scaffolds	期刊论文	JY Li, TT Xu, Q Wang, JC Ren, K Duan, YD Mu, J Weng*\|
28	Preparation and characterization of hydroxyapatite porous scaffold with controlled multi-scale structure	会议论文	Ke Duan\|Li Sang\|Lin Li\|Jie Weng\|
29	致密羟基磷灰石球粒的制备及其生物学性能研究	期刊论文	李金雨\|鲁雄\|冯波\|翁杰\|
30	生物材料表面微纳结构对成骨相关细胞的影响	期刊论文	鲁雄\|冯波\|翁杰\|冷扬\|
31	生物修饰多孔羟基磷灰石体系的研发	奖励
32	Tissue engineered bone constructs in vivo using hydroxyapatite scaffolds with complimentary porous structures	会议论文	Chengdong Zhang\|Cong Zhang\|Yimin Yao\|Jie Weng\|
33	Hydrothermal fabrication of hierarchical hollow hydroxyapatite microspheres with nano-structured surface assisted by inositol hexakisphosphate	会议论文	DQ Xiao\|CD Zhang\|YK Fu\|K Duan,\|X Lu\|J Weng\|
34	Molecular Docking Characterization of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop with Hydroxyapatite	期刊论文	Xiao, Dongqin\|Duan, Rongquan\|Zhi, Wei\|Weng, Jie\|
35	The Biological Responses of Hydroxyapatite Spherules Accumulating Scaffolds with Different Surface Textures	会议论文
36	Study on themicrostructure and biocompatibility of inositol hexakisphosphate-modifiedtitanium surface	期刊论文	Xiao DQ, Tan Z, Zhang CD, Guo TL, Duan K, Weng J*\|
37	Synthesis of flower-like hydroxyapatite microspheres: morphogenesis via copper doping	会议论文
38	羟基磷灰石微纳结构对蛋白吸附的影响	期刊论文	付亚康, 周雪, 肖东琴, 匙峰, 卢晓英, 翁杰*\|
39	Comparative studies on ectopic bone formation in porous hydroxyapatite scaffolds with complementary pore structures	期刊论文	Duan, Ke\|Duan, Rongquan\|Mu, Yandong\|Weng, Jie\|
40	Vascularized natural bone-like grafts harvested by implanting porous bioceramic scaffolds at non-osseous sites and their application in repairing canine limb defects	会议论文	Peng Huang \| Bo Feng \|Shuxin Qu\|Xiaohong Li\|
41	采用糖球颗粒作为造孔剂制备多孔HA支架	会议论文
42	Comparative Studies on Pore Shapes of Interconnected Porous Hydroxyapatite Scaffolds in Promoting Heterogeneous Bone Formation in Dogs	会议论文
43	蜡球造孔法制备多孔 HA 陶瓷支架及其性能优化	期刊论文	智伟\|鲁雄\|贾治彬\|翁杰\|
44	掺铜羟基磷灰石微球的制备及表征	期刊论文	姚宁\|鲁雄\|郑晓彤\|翁杰\|

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