新型pH响应载体转导靶向Met/VEGFR2受体基因抑制恶性胶质瘤及其放疗增敏功能及机制研究

81673008
2016
H1821.肿瘤治疗抵抗
姚宏
面上项目
教授
昆明医科大学
52万元
pH响应纳米载体;Met/VEGFR2;基因治疗;放疗增敏;恶性神经胶质瘤
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 一种吲哚螺吡咯衍生物的合成及其作为肿瘤治疗药物的应用 专利 姚宏;郑骏年;朱松磊;白津;王静;郭毛毛;刘鸿志
2 Anti-malarial atovaquone exhibits anti-tumor effects by inducing DNA damage in hepatocellular carcinoma 期刊论文 Gao Xiaoge;Liu Xiangye;Shan Wenhua;Liu Qian;Wang Chao;Zheng Jiwei;Yao Hong;Tang Renxian;Zheng Junnian
3 Oral administration of indole substituted dipyrido[2,3-d]pyrimidine derivative exhibits anti-tumor activity via inhibiting AKT and ERK1/2 on hepatocellular carcinoma 期刊论文 Gao Xiaoge;Cen Lanqi;Li Fangyuan;Wen Ren;Yan Hongru;Yao Hong;Zhu Songlei
4 A novel galactose-PEG-conjugated biodegradable copolymer is an efficient gene delivery vector for immunotherapy of hepatocellular carcinoma 期刊论文 Liu Ling;Zong Zhi Min;Liu Qian;Jiang Shuang Shuang;Zhang Qian;Cen Lan Qi;Gao Jian;Gao Xiao Ge;Huang Jian Dong;Liu Yi;Yao Hong
5 An oral 2-hydroxypropyl-beta-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma 期刊论文 Gao Xiaoge;Wei Mengxue;Shan Wenhua;Liu Qian;Gao Jian;Liu Yong;Zhu Songlei;Yao Hong
6 抗癌融合蛋白及其药物组合物和应用 专利 姚宏;高晓鸽;段锐;张健
7 H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma 期刊论文 Zhang Wenyan;Duan Rui;Zhang Jian;Cheung William K C;Gao Xiaoge;Zhang Raymond;Zhang Qing;Wei Mengxue;Wang Gang;Zhang Qian;Mei Peng jin;Chen Hong lin;Kung Hsiangfu;Lin Marie C;Shen Zan;Zheng Junnian;Zhang Longzhen;Yao Hong
8 Peglated-H1/pHGFK1 nanoparticles enhance anti-tumor effects of sorafenib by inhibition of drug-induced autophagy and stemness in renal cell carcinoma 期刊论文 Gao Xiaoge;Jiang Pin;Zhang Qian;Liu Qian;Jiang Shuangshuang;Liu Ling;Guo Maomao;Cheng Qian;Zheng Junnian;Yao Hong
9 A prognosis and impact factor analysis of DC-CIK cell therapy for patients with hepatocellular carcinoma undergoing postoperative TACE 期刊论文 Zhang Jian;Li Huizhong;Gao Dazhi;Zhang Baofu;Zheng Maojin;Lun Mingyin;Wei Mengxue;Duan Rui;Guo Maomao;Hua Jiajun;Liu Qian;Bai Jin;Liu Hui;Zheng Junnian;Yao Hong
10 一种多聚阳离子包被腺病毒组合物的制备方法及其应用 专利 姚宏
11 JNK1/2 and ERK1/2 provides vital clues about tumor recurrence and survival in hepatocellular carcinoma patients 期刊论文 Gao Xiaoge;Shan Wenhua;Liu Xiangye;Zhang Jian;Zheng Junnian;Yao Hong
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