基于点击化学的智能型蛋白药物缓释制剂的构建及其免疫协同抗肿瘤的研究

81903546
2019
H3408.药剂学
刘小文
青年科学基金项目
研究员
暨南大学
20万元
蛋白类药物;靶向运输;可控释放;干扰素ɑ;PD-L1抑制剂
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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4 Green synthesis of silver nanoparticles and their antibacterial effects 期刊论文 Xiaoqian Xin;Chunli Qi;Liang Xu;Qin Gao;Xiaowen Liu
5 Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response 期刊论文 Peidi Yin;Huifeng Li;Chao Ke;Guangxu Cao;Xiaoqian Xin;Junjiao Hu;Xiangran Cai;Lingfeng Li;Xiaowen Liu;Bin Du
6 Microneedle-mediated drug delivery for cutaneous diseases 期刊论文 Jian Chen;Hui Ren;Pan Zhou;Shuai Zheng;Bin Du;Xiaowen Liu;Fei Xiao
7 pH-Sensitive Biomaterials for Drug Delivery 期刊论文 Shijie Zhuo;Feng Zhang;Junyu Yu;Xican Zhang;Guangbao Yang;Xiaowen Liu
8 Bioresponsive nanomedicines based on dynamic covalent bonds 期刊论文 Xiaoqian Xin;Zhongxia Zhang;Xican Zhang;Jian Chen;Xi Lin;Pinghua Sun;Xiaowen Liu
9 Click chemistry-conjugated protein-drug micelles with anti-ferroptotic and anti-inflammatory properties promote regeneration in spinal cord injury 期刊论文 Pan Zhou;Xican Zhang;Xiaoqian Xin;Jinpei Yang;Qiaofei Pan;Chao Liu;Yang Liu;Xiang Yu;Zhizhong Li;Genlong Jiao;Xiaowen Liu
10 Protein-drug conjugate programmed by pH-reversible linker for tumor hypoxia relief and enhanced cancer combination therapy 期刊论文 Xican Zhang;Liangzhu Feng;Ziliang Dong;Xiaoqian Xin;Zhijuan Yang;Dashi Deng;Ernst Wagner;Zhuang Liu;Xiaowen Liu
11 Protein nanogels with enhanced pH-responsive dynamics triggered by remote NIR for systemic protein delivery and programmable controlled release 期刊论文 Zhang Xican;Zhou Pan;Zhuo Shijie;Zhang Feng;Yu Junyu;Liu Xiaowen
12 General method to stabilize mesophilic proteins in hyperthermal water 期刊论文 Xiaoqian Xin;Youwei Xu;Hu Shi;Xiaowen Liu
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