E3泛素连接酶UBE3B通过HIF-2α调控乳腺癌生长与转移的分子机制研究
81902691
2019
H1808.肿瘤微环境
陈颜
青年科学基金项目
教授
暨南大学
21万元
肿瘤低氧;HIF-2α;泛素化;乳腺癌;UBE3B
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | USP5 promotes breast cancer cell proliferation and metastasis by stabilizing HIF2α | 期刊论文 | Xiong Liu;Weixiao Huang;Yao Zhang;Mingxia Deng;Guangqiang Li;Guo Chen;Li Yu;Lai Jin;Tongzheng Liu;Yijie Wang;Chen Yan |
| 2 | Romance of the three kingdoms in hypoxia: HIFs, epigenetic regulators, and chromatin reprogramming. | 期刊论文 | Yan Chen;Min Liu;Yanling Niu;Yijie Wang |
| 3 | Deubiquitinating enzyme USP9X regulates metastasis and chemoresistance in triple‐negative breast cancer by stabilizing Snail1 | 期刊论文 | Tangming Guan;Xiao Yang;Hui Liang;Jiayi Chen;Yan Chen;Yingjie Zhu;Tongzheng Liu |
| 4 | The intricate interplay between HIFs, ROS, and the ubiquitin system in the tumor hypoxic microenvironment | 期刊论文 | Yijie Wang;Xiong Liu;Weixiao Huang;Junjie Liang;Yan Chen |
| 5 | The multifaceted functions of RNA helicases in the adaptive cellular response to hypoxia: from mechanisms to therapeutics | 期刊论文 | Yijie Wang;Guangqiang Li;Mingxia Deng;Xiong Liu;Weixiao Huang;Yao Zhang;Min Liu;Yan Chen |
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