基于骨质疏松模型猴的大麻素受体治疗靶点的可视化研究
81871383
2018
H2704.核医学诊断与治疗
徐浩
面上项目
教授
暨南大学
57万元
大麻素受体;多模态影像;正电子示踪剂;恒河猴;骨质疏松
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Synthesis and preliminary evaluation of a novel positron emission tomography (PET) ligand for imaging fatty acid amide hydrolase (FAAH) | 期刊论文 | Zhen Chen;Lu Hou;Jiefeng Gan;Qijun Cai;Weijian Ye;Jiahui Chen;Zhiqiang Tan;Chao Zheng;Guocong Li;Hao Xu;Christopher J. Fowler;Steven H. Liang;Lu Wang |
| 2 | The precision study of dual energy X-ray absorptiometry for bone mineral density and body composition measurements in female cynomolgus monkeys | 期刊论文 | Bin Guo;Qijun Cai;Jinci Mai;Lu Hou;Chunyuan Zeng;Jiefeng Gan;Zhiqiang Tan;Yuefeng Li;Yong Cheng;Jingjie Shang;Yongjin Tang;Xueying Ling;Jian Gong;Lu Wang;Hao Xu |
| 3 | PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide | 期刊论文 | Hu Kuan;Shang Jingjie;Xie Lin;Hanyu Masayuki;Zhang Yiding;Yang Zhimin;Xu Hao;Wang Lu;Zhang Ming-Rong |
| 4 | A concisely automated synthesis of TSPO radiotracer [18F] FDPA based on spirocyclic iodonium ylide method and validation for human use | 期刊论文 | Lu Wang;Shaobo Yao;Ruikun Tang;Honghao Zhu;Lingling Zhang;Jian Gong;Qiusong Chen;Thomas Lee Collier;Hao Xu;Steven H. Liang |
| 5 | A fluorinated azine as a versatile scaffold for the development of Cu (II)-specific multi-functional imaging probes | 期刊论文 | Ye Weijian;Xie Mengting;Wei Junjie;Li Guocong;Tang Yongjin;Hou Lu;Wang Lu;Yu Huijuan;Lee Chi-Sing;Xu Hao |
| 6 | Easily automated radiosynthesis of [18F]P10A-1910 and its clinical translation to quantify phosphodiesterase 10A in human brain | 期刊论文 | Huiyi Wei;Junjie Wei;Shaojuan Zhang;Shiliang Dong;Guocong Li;Wenqing Ran;Chenchen Dong;Weibin Zhang;Chao Che;Wenzhao Luo;Hao Xu;Zhiyong Dong;Jinghao Wang;Lu Wang |
| 7 | A population stereotaxic positron emission tomography brain template for the macaque and its application to ischemic model | 期刊论文 | Binbin Nie;Lu Wang;Yichao Hu;Shengxiang Liang;Zhiqiang Tan;Pei Chai;Yongjin Tang;Jingjie Shang;Zhangsheng Pan;Xudong Zhao;Xiaofei Zhang;Jianxian Gong;Chao Zheng;Hao Xu;Hsiao-Ying Wey;Steven H.Liang;Baoci Shan |
| 8 | Imaging the trace amine-associated receptor 1 by positron emission tomography | 期刊论文 | Sun Jiyun;Chen Jiahui;Kumata Katsushi;Xiao Zhiwei;Rong Jian;Haider Ahmed;Shao Tuo;Wang Lu;Xu Hao;Zhang Ming-Rong;Liang Steven H. |
| 9 | Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators | 期刊论文 | Jiyun Sun;Katsushi Kumata;Zhen Chen;Yiding Zhang;Jiahui Chen;Akiko Hatori;Hualong Fu;Jian Rong;Xiaoyun Deng;Tomoteru Yamasaki;Lin Xie;Kuan Hu;Masayuki Fujinaga;Qingzhen Yu;Tuo Shao;Thomas Lee Collier;Lee Josephson;Yihan Shao;Yunfei Du;Lu Wang;Hao Xu;Ming-Rong Zhang;Steven H. Liang |
| 10 | Recent developments on PET radiotracers for TSPO and their applications in neuroimaging | 期刊论文 | Lingling Zhang;Kuan Hu;Tuo Shao;Lu Hou;Shaojuan Zhang;Weijian Ye;Lee Josephson;Jeffrey H. Meyer;Ming-Rong Zhang;Neil Vasdev;Jinghao Wang;Hao Xu;Lu Wang;Steven H. Liang |
| 11 | Analysis of serum bone turnover markers in female cynomolgus monkeys of different ages | 期刊论文 | Ying Li;Qijun Cai;Chenchen Dong;Lu Hou;Yingxin Li;Bin Guo;Chunyuan Zeng;Yong Cheng;Jingjie Shang;Xueying Ling;Jian Gong;Hao Xu |
| 12 | Radiosynthesis and preliminary evaluation of 11C-labeled 4-cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-benzo[e] [1,2,4] thiadiazine 1,1-dioxide for PET imaging AMPA receptors | 期刊论文 | J. Chen;J. Gan;J. Sun;Z. Chen;H. Fu;J. Rong;X. Deng;J. Shang;J. Gong;T. Shao;L. Collier;L. Wang;H. Xu;S. H. Liang |
| 13 | Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development | 期刊论文 | Lu Hou;Jian Rong;Ahmed Haider;Daisuke Ogasawara;Cassis Varlow;Michael A. Schafroth;Linjing Mu;Jiefeng Gan;Hao Xu;Christopher J. Fowler;Ming-Rong Zhang;Neil Vasdev;Simon M. Ametamey;Benjamin F. Cravatt;Lu Wang;Steven H. Liang |
| 14 | Observer agreement and accuracy of 18F-sodium fluoride PET/computed tomography in the diagnosis of skull-base bone invasion and osseous metastases in newly diagnosed nasopharyngeal carcinoma | 期刊论文 | JingXing Xiao;Dong Wang;Bin Guo;Lu Wang;Min Su;Hao Xu |
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