靶向CREB1-TGFβ2-ERK信号通路的欧前胡素在食管癌侵袭转移中的作用及机制研究
81803551
2018
H3505.抗肿瘤药物药理
许雯雯
青年科学基金项目
教授
暨南大学
21万元
食管癌转移;定量蛋白质组学;天然产物的高通量筛选;CREB1-TGFβ2-ERK信号通路;欧前胡素
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Benzethonium chloride suppresses lung cancer tumorigenesis through inducing p38-mediated cyclin D1 degradation | 期刊论文 | Huang Xiao-Hui;Wang Yang;Hong Pan;Yang Jie;Zheng Can-Can;Yin Xing-Feng;Song Wen-Bo;Xu Wen Wen;Li Bin;He Qing-Yu |
| 2 | Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1 | 期刊论文 | Zheng Cancan;Zhu Yidong;Liu Qinwen;Luo Tingting;Xu Wenwen |
| 3 | 食管癌微环境研究 | 会议论文 | 许雯雯 |
| 4 | Lomerizine 2HCl inhibits cell proliferation and induces protective autophagy in colorectal cancer via the PI3K/Akt/mTOR signaling pathway | 期刊论文 | Tan XiangPeng;He Yan;Huang YunNa;Zheng CanCan;Li JunQi;Liu QinWen;He MingLiang;Li Bin;Xu WenWen |
| 5 | Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling | 期刊论文 | Xu Wen Wen;Zheng Can Can;Huang Yun Na;Chen Wen You;Yang Qing Sheng;Ren Jia Yi;Wang Yue Ming;He Qing Yu;Liao Hua Xin;Li Bin |
| 6 | Direct targeting of HSP90 with daurisoline destabilizes beta-catenin to suppress lung cancer tumorigenesis | 期刊论文 | Huang Xiao-Hui;Yan Xin;Zhang Qi-Hua;Hong Pan;Zhang Wei-Xia;Liu Ya-Ping;Xu Wen Wen;Li Bin;He Qing-Yu |
| 7 | Epigenetics in Esophageal Cancer: From Mechanisms to Therapeutics | 期刊论文 | Liao Long;Yao Zi-Ting;Fang Wang-Kai;He Qing-Yu;Xu Wen Wen;Li Bin |
| 8 | Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis | 期刊论文 | Hong Pan;Liu Qin-Wen;Xie Yao;Zhang Qi-Hua;Liao Long;He Qing-Yu;Li Bin;Xu Wen Wen |
| 9 | Targeting PP2A with lomitapide suppresses colorectal tumorigenesis through the activation of AMPK/Beclin1-mediated autophagy | 期刊论文 | Zuo Qian;Liao Long;Yao Zi-Ting;Liu Ya-Ping;Wang Ding-Kang;Li Shu-Jun;Yin Xing-Feng;He Qing-Yu;Xu Wen-Wen |
| 10 | 食管癌微环境 | 会议论文 | 许雯雯 |
| 11 | Direct Targeting of CREB1 with Imperatorin Inhibits TGF beta 2-ERK Signaling to Suppress Esophageal Cancer Metastasis | 期刊论文 | Xu Wen Wen;Huang Zhi-Hao;Liao Long;Zhang Qi-Hua;Li Jun-Qi;Zheng Can-Can;He Yan;Luo Ting-Ting;Wang Yang;Hu Hui-Fang;Zuo Qian;Chen Wen-You;Yang Qing-Sheng;Zhao Jian-Fu;Qin Yan-Ru;Xu Li-Yan;Li En-Min;Liao Hua-Xin;Li Bin;He Qing-Yu |
| 12 | 欧前胡素在制备抑制食管癌肿瘤的药物中的应用 | 专利 | 李斌;黄智豪;何庆瑜;许雯雯 |
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