晚期氧化蛋白产物（AOPP）刺激下滋养细胞外泌体LncRNA AC092115.3调 控EGR1/HSPA1B在子痫前期发病中的机制研究

81971413
2019
H0417.妊娠相关性疾病
钟梅
面上项目
教授
南方医科大学
51万元
晚期氧化蛋白产物;生物标记物;LncRNA;子痫前期;外泌体
2020-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Cyclophilin A inhibits trophoblast migration and invasion in vitro and vivo through p38/ERK/JNK pathways and causes features of preeclampsia in mice 期刊论文 Haoyue Hu;Jiayi Jiang;Qian Chen;Songren Wei;Mian Liu;Xia Chen;Cuixia Fan;Jing Ma;Wenqian Chen;Xuefei Wang;Mei Zhong
2 Association of lncRNA SH3PXD2A-AS1 with preeclampsia and its function in invasion and migration of placental trophoblast cells 期刊论文 Chen Qian;Jiang Sijia;Liu Haihua;Gao Yue;Yang Xiaoxue;Ren Zhonglu;Gao Yunfei;Xiao Lu;Hu Haoyue;Yu Yanhong;Yang Xinping;Zhong Mei
3 Preeclampsia-Associated lncRNA INHBA-AS1 Regulates the Proliferation, Invasion, and Migration of Placental Trophoblast Cells 期刊论文 Jiang Sijia;Chen Qian;Liu Haihua;Gao Yue;Yang Xiaoxue;Ren Zhonglu;Gao Yunfei;Xiao Lu;Zhong Mei;Yu Yanhong;Yang Xinping
4 Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia 期刊论文 Qian Chen;Jiexing He;Haihua Liu;Qiuyu Huang;Shuoshi Wang;Ailan Yin;Shuying Chen;Xinyang Shen;Yanxuan Xiao;Haoyue Hu;Jiayi Jiang;Wenqian Chen;Song Wang;Zhenqin Huang;Jiaqi Li;You Peng;Xiaocong Wang;Xinping Yang;Zhijian Wang;Mei Zhong
5 Cyclosporin A alleviates trophoblast apoptosis and senescence by promoting autophagy in preeclampsia 期刊论文 Haoyue Hu;Wenqian Chen;Zixin Tao;Zhiju Li;Jiexing He;You Peng;Jing Ma;Huiting Wen;Jing Li;Xuefei Wang;Mei Zhong
6 AOPPs induce HTR-8/SVneo cell apoptosis by downregulating the Nrf-2/ARE/HO-1 anti-oxidative pathway: Potential implications for preeclampsia 期刊论文 Shuying Chen;Qian Yin;Haoyue Hu;Qian Chen;Qitao Huang;Mei Zhong
7 子痫前期患者血清晚期氧化蛋白产物及髓过氧化物酶表达水平及其临床意义 期刊论文 王硕石;钟梅;廖义鸿
8 CyPA interacts with SERPINH1 to promote extracellular matrix production and inhibit epithelial-mesenchymal transition of trophoblast via enhancing TGF-β/Smad3 pathway in preeclampsia 期刊论文 Haoyue Hu;Jing Ma;Zhiju Li;Ziling Ding;Wenqian Chen;You Peng;Zixin Tao;Lu Chen;Manling Luo;Chichiu Wang;Xuefei Wang;Jing Li;Mei Zhong
9 GLP-1介导PI3K/Akt通路拮抗AOPP诱导HTR-8/SVneo细胞凋亡的作用 期刊论文 王硕石;钟梅
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