BRG1通过与Wnt/β-catenin信号通路的交互作用诱导肾小管上皮细胞衰老及肾纤维化形成
81900607
2019
H0502.泌尿系统损伤与修复
罗丛伟
青年科学基金项目
主治医师
南方医科大学
22万元
细胞衰老;BRG1;肾纤维化;衰老相关分泌表型;Wnt/β-catenin信号通路
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/beta-catenin/autophagy axis | 期刊论文 | Gong Wangqiu;Luo Congwei;Peng Fenfen;Xiao Jing;Zeng Yiqun;Yin Bohui;Chen Xiaowen;Li Shuting;He Xiaoyang;Liu Yanxia;Cao Huihui;Xu Jiangping;Long Haibo |
| 2 | circRNA_010383 Acts as a Sponge for miR-135a, and Its Downregulated Expression Contributes to Renal Fibrosis in Diabetic Nephropathy | 期刊论文 | Peng Fenfen;Gong Wangqiu;Li Shuting;Yin Bohui;Zhao Chen;Liu Wenting;Chen Xiaowen;Luo Congwei;Huang Qianying;Chen Ting;Sun Lingzhi;Fang Shun;Zhou Weidong;Li Zhijian;Long Haibo |
| 3 | FOXO3a accumulation and activation accelerate oxidative stress-induced podocyte injury | 期刊论文 | Chen Xiaowen;Liu Wenting;Xiao Jing;Zhang Ying;Chen Yihua;Luo Congwei;Huang Qianyin;Peng Fenfen;Gong Wangqiu;Li Shuting;He Xiaoyang;Zhuang Yiyi;Wu Na;Liu Yanxia;Wang Yuxian;Long Haibo |
| 4 | Parthenolide, an NF-kappa B inhibitor, alleviates peritoneal fibrosis by suppressing the TGF-beta/Smad pathway | 期刊论文 | Zhang Ying;Huang Qianyin;Chen Yihua;Peng Xuan;Wang Yuxian;Li Shuting;Wu Jiayu;Luo Congwei;Gong Wangqiu;Yin Bohui;Xiao Jing;Zhou Weidong;Peng Fenfen;Long Haibo |
| 5 | Micheliolide ameliorates diabetic kidney disease by inhibiting Mtdh-mediated renal inflammation in type 2 diabetic db/db mice | 期刊论文 | Liu Wenting;Chen Xiaowen;Wang Yuxian;Chen Yihua;Chen Sijia;Gong Wangqiu;Chen Ting;Sun Lingzhi;Zheng Chenghao;Yin Bohui;Li Shuting;Luo Congwei;Huang Qianyin;Xiao Jing;Xu Zhaozhong;Peng Fenfen;Long Haibo |
| 6 | Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-kappa B/NLRP3 Axis in Renal Tubular Epithelial Cells | 期刊论文 | Lei Xianghong;Li Shuting;Luo Congwei;Wang Yuxian;Liu Yanxia;Xu Zhaozhong;Huang Qianyin;Zou Fangqin;Chen Yihua;Peng Fenfen;Long Haibo |
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