LKB1调节免疫微环境诱导肺癌抗PD-1免疫治疗原发耐药的分子机制研究
81802863
2018
H1806.肿瘤免疫
董忠谊
青年科学基金项目
副主任医师
南方医科大学
21万元
肺肿瘤;耐药;免疫微环境;驱动基因;免疫治疗
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Integrative evaluation of primary and metastatic lesion spectrum to guide anti-PD-L1 therapy of non-small cell lung cancer: results from two randomized studies | 期刊论文 | Ma Si-Cong;Tang Xin-Ran;Long Li-Li;Bai Xue;Zhou Jian-Guo;Duan Zhi-Jiao;Wang Jian;Fu Qiang John;Zhu Hong-Bo;Guo Xue-Jun;Zhang Yan-Pei;Guo Ze-Qin;Wu De-Hua;Dong Zhong-Yi |
| 2 | Combination of TMB and CNA Stratifies Prognostic and Predictive Responses to Immunotherapy Across Metastatic Cancer. | 期刊论文 | Liu Li;Bai Xue;Wang Jian;Tang Xin-Ran;Wu De-Hua;Du Sha-Sha;Du Xiu-Ju;Zhang Yao-Wei;Zhu Hong-Bo;Fang Yuan;Guo Ze-Qin;Zeng Qin;Guo Xue-Jun;Liu Zhu;Dong Zhong-Yi |
| 3 | Development and interpretation of a pathomics-based model for the prediction of microsatellite instability in Colorectal Cancer | 期刊论文 | Rui Cao;Fan Yang;Si-Cong Ma;Li Liu;Yu Zhao;Yan Li;De-Hua Wu;Tongxin Wang;Wei-Jia Lu;Wei-Jing Cai;Hong-Bo Zhu;Xue-Jun Guo;Yu-Wen Lu;Jun-Jie Kuang;Wen-Jing Huan;Wei-Min Tang;Kun Huang;Junzhou Huang;Jianhua Yao;Zhong-Yi Dong |
| 4 | Development and validation of a genomic mutation signature to predict response to PD-1 inhibitors in non-squamous NSCLC: a multicohort study | 期刊论文 | Bai Xue;Wu De-Hua;Ma Si-Cong;Wang Jian;Tang Xin-Ran;Kang Shuai;Fu Qiang John;Cao Chuan-Hui;Luo He-San;Chen Yu-Han;Zhu Hong-Bo;Yan Hong-Hong;Wu Yi-Long;Dong Zhong-Yi |
| 5 | HPV-positive status associated with inflamed immune microenvironment and improved response to anti-PD-1 therapy in head and neck squamous cell carcinoma | 期刊论文 | Wang Jian;Sun Hao;Zeng Qin;Guo Xue-Jun;Wang Hui;Liu Huan-Huan;Dong Zhong-Yi |
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