靶向抑制flot-2对破骨细胞生成和骨破坏的影响及分子免疫机制研究
81773740
2017
H3504.抗炎与免疫药物药理
李晓娟
面上项目
教授
南方医科大学
52万元
分子免疫机制;flot-2;骨破坏;破骨细胞
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Oridonin ameliorates RANKL-induced osteoclastogenesis and inflammation-induced bone loss by suppressing DC-STAMP | 会议论文 | Binhua Zou;Jiehuang Zheng;Wende Deng;Yanhui Tan;Qin Yang;Minhong Ke;Zongbao Ding;Xiaojuan Li |
| 2 | Oridonin ameliorates inflammation-induced bone loss in mice via suppressing DC-STAMP expression | 期刊论文 | Zou Bin-hua;Tan Yan-hui;Deng Wen-de;Zheng Jie-huang;Yang Qin;Ke Min-hong;Ding Zong-bao;Li Xiao-juan |
| 3 | Flot2抑制剂在抑制破骨细胞形成和/或破骨活性中的应用 | 专利 | 李晓娟;邹斌华;郑洁煌 |
| 4 | 骨免疫疾病相关药物研究和新靶点发现 | 会议论文 | 李晓娟 |
| 5 | Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLC gamma 1-Ca2+-NFATc1 signaling pathway | 期刊论文 | Zeng Xiang-zhou;Zhang Yue-yang;Yang Qin;Wang Song;Zou Bin-hua;Tan Yan-hui;Zou Min;Liu Shu-wen;Li Xiao-juan |
| 6 | Kirenol inhibits RANKL-induced osteoclastogenesis and prevents ovariectomized-induced osteoporosis via suppressing the Ca2+-NFATc1 and Cav-1 signaling pathways | 期刊论文 | Zou Binhua;Zheng Jiehuang;Deng Wende;Tan Yanhui;Jie Ligang;Qu Yuan;Yang Qin;Ke Minhong;Ding Zongbao;Chen Yan;Yu Qinghong;Li Xiaojuan |
| 7 | A mutation of cysteine 46 in IKK-beta promotes mPGES-1 and caveolin-1 expression to exacerbate osteoclast differentiation and osteolysis | 期刊论文 | Zou Binhua;Zhang Yueyang;Li Ting;Liu Juan;Deng Wende;Tan Yanhui;Yang Qin;Ding Zongbao;Liao Kangsheng;Xu Jialan;Pan Hudan;Li Xiaojuan;Liu Liang |
| 8 | Sinomenine inhibits osteolysis in breast cancer by reducing IL-8/CXCR1 and c-Fos/NFATc1 signaling | 期刊论文 | Zhang Yueyang;Zou Binhua;Tan Yanhui;Su Jianbing;Wang Yiyuan;Xu Jialan;Tao Lei;Zhou Hua;Liu Liang;Li Xiaojuan |
| 9 | A marine fungus-derived nitrobenzoyl sesquiterpenoid suppresses receptor activator of NF-kappa B ligand-induced osteoclastogenesis and inflammatory bone destruction | 期刊论文 | Tan Yanhui;Deng Wende;Zhang Yueyang;Ke Minhong;Zou Binhua;Luo Xiaowei;Su Jianbin;Wang Yiyuan;Xu Jialan;Nandakumar Kutty Selva;Liu Yonghong;Zhou Xuefeng;Li Xiaojuan |
| 10 | 破骨细胞融合相关分子的研究进展 | 期刊论文 | 邹斌华;郑洁煌;李晓娟 |
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