亚甲基四氢叶酸还原酶基因C677T多态性预测中国高血压人群新发恶性肿瘤风险
81402735
2014
H3010.非传染病流行病学
秦献辉
青年科学基金项目
研究员
南方医科大学
23万元
肿瘤发生;叶酸补充;高血压;亚甲基四氢叶酸还原酶基因C677T多态性;队列研究
2015-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Association of serum uric acid with increased risk of cancer among hypertensive Chinese | 期刊论文 | Yang Juan;Wang Yupeng;Zhao Qianqian;Zhang Xianglin;Wang Xiaobin;Qin Xianhui;Zhang Rong;Shen Lin;Jiang Xiaodong;Jiang Hua;Lei Yu;Wang Binyan;Gu Jin;Hou Fan Fan;Huo Yong;Gao Wei;Xu Xiping |
| 2 | Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions Effect modification by MTHFR C677T polymorphism | 期刊论文 | Xu Benjamin;Kong Xiangyi;Xu Richard;Song Yun;Liu Lishun;Zhou Ziyi;Gu Rui;Shi Xiuli;Zhao Min;Huang Xiao;He Mingli;Fu Jia;Cai Yefeng;Li Ping;Cheng Xiaoshu;Wu Changyan;Chen Fang;Zhang Yan;Tang Genfu;Qin Xianhui;Wang Binyan;Xue Hao;Chen Yundai;Tian Ye;Sun Ningling;Cui Yimin;Hou Fan Fan;Li Jianping;Huo Yong |
| 3 | Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial. | 期刊论文 | Qin Xianhui;Shen Lin;Zhang Rong;Li Youbao;Wang Xiaobin;Wang Binyan;Jiang Xiaodong;Jiang Hua;Lei Yu;Hou Fan Fan;Gu Jin;Huo Yong |
| 4 | Impact of achieved blood pressure on renal function decline and first stroke in hypertensive patients with chronic kidney disease | 期刊论文 | Li Y;Liang M;Jiang C;Wang G;Li J;Zhang Y;Fan F;Sun N;Cui Y;He M;Tang G;Yin D;Cheng X;Wang B;Huo Y;Xu X;Hou FF;Xu X;Qin X |
| 5 | Risk factors for renal function decline in adults with normal kidney function: a 7-year cohort study. | 期刊论文 | Qin Xianhui;Wang Yuejuan;Li Youbao;Xie Di;Tang Genfu;Wang Binyan;Wang Xiaobin;Xu Xin;Xu Xiping;Hou Fanfan |
| 6 | Optimal systolic blood pressure levels for primary prevention of stroke in general hypertensive adults: findings from the China Stroke Primary Prevention Trial (CSPPT) | 期刊论文 | Fan Fangfang;Yuan Ziwen;Qin Xianhui;Li Jianping;Zhang Yan;Li Youbao;Yu Tao;Ji Meng;Ge Junbo;Zheng Meili;Yang Xinchun;Bao Huihui;Cheng Xiaoshu;Gu Dongfeng;Zhao Dong;Wang Jiguang;Sun Ningling;Chen Yundai;Wang Hong;Wang Xiaobin;Parati Gianfranco;Hou Fan Fan;Xu Xiping;Wang Xian;Zhao Gang;Huo Yong |
| 7 | Effect of folic acid supplementation on risk of new-onset diabetes in adults with hypertension in China: Findings from the China Stroke Primary Prevention Trial (CSPPT). | 期刊论文 | Qin Xianhui;Li Jianping;Zhang Yan;Chen Dafang;Wang Binyan;He Mingli;Fu Jia;Tang Genfu;Cai Yefeng;Shi Xiuli;Xu Xin;Hou Fan Fan;Wang Xiaobin;Huo Yong |
| 8 | Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients | 期刊论文 | Li Youbao;Qin Xianhui;Luo Lian;Wang Binyan;Huo Yong;Hou Fan Fan;Xu Xin |
| 9 | Prospective study of serum uric acid levels and stroke in a Chinese hypertensive cohort | 期刊论文 | Shi Xiuli;Yang Juan;Wang Liwei;Zhao Min;Zhang Chunyan;He Mingli;Qin Xianhui;Tang Genfu;Li Jianping;Zhang Yan;Huo Yong;Cai Yefeng;Zhao Gang;Dong Qiang;Xu Xiping;Wang Binyan;Fu Jia;Wang Kai |
| 10 | 中国脑卒中高发成因和精准预防的研究与转化 | 奖励 | 霍勇;李建平;侯凡凡;张岩;秦献辉;黄一宁;唐根福;何明利;傅佳;陈韵岱;李小鹰;王建安;肖传实;赵连友;程晓曙;蔡业峰;范芳芳;王滨燕;徐希平;蒋捷;李康;史秀丽 |
| 11 | Homocysteine and Stroke Risk Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention | 期刊论文 | Zhao Min;Wang Xiaobin;He Mingli;Qin Xianhui;Tang Genfu;Huo Yong;Li Jianping;Fu Jia;Huang Xiao;Cheng Xiaoshu;Wang Binyan;Hou Fan Fan;Sun Ningling;Cai Yefeng |
| 12 | Relationship of MTHFR gene 677C --> T polymorphism, homocysteine, and estimated glomerular filtration rate levels with the risk of new-onset diabetes. | 期刊论文 | Qin Xianhui;Li Youbao;Yuan Hui;Xie Di;Tang Genfu;Wang Binyan;Wang Xiaobin;Xu Xin;Xu Xiping;Hou Fanfan |
| 13 | Impact of achieved blood pressure on first stroke in uncomplicated grade 1 hypertension | 期刊论文 | Qin Xianhui;Li Youbao;Sun Ningling;He Mingli;Tang Genfu;Yin Delu;Wang Jiguang;Liang Min;Wang Binyan;Huo Yong;Xu Xin;Xu Xiping;Hou Fan Fan |
| 14 | Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention | 期刊论文 | Xu Richard B.;Kong Xiangyi;Xu Benjamin P.;Song Yun;Ji Meng;Zhao Min;Huang Xiao;Li Ping;Cheng Xiaoshu;Chen Fang;Zhang Yan;Tang Genfu;Qin Xianhui;Wang Binyan;Hou Fan Fan;Dong Qiang;Chen Yundai;Yang Tianlun;Sun Ningling;Li Xiaoying;Zhao Lianyou;Ge Junbo;Ji Linong;Huo Yong;Li Jianping |
| 15 | Independent and Joint Effect of Brachial-Ankle Pulse Wave Velocity and Blood Pressure Control on Incident Stroke in Hypertensive Adults | 期刊论文 | Song Yun;Xu Benjamin;Xu Richard;Tung Renee;Frank Eric;Tromble Wayne;Fu Tong;Zhang Weiyi;Yu Tao;Zhang Chunyan;Fan Fangfang;Zhang Yan;Li Jianping;Bao Huihui;Cheng Xiaoshu;Qin Xianhui;Tang Genfu;Chen Yundai;Yang Tianlun;Sun Ningling;Li Xiaoying;Zhao Lianyou;Hou Fan Fan;Ge Junbo;Dong Qiang;Wang Binyan;Xu Xiping;Huo Yong |
| 16 | Relationship of diabetes with renal dysfunction in hypertensive adults | 期刊论文 | Wang Yuejuan;Zhong Biyan;Li Youbao;Qin Xianhui;Wang Binyan;Xu Xin;Hou Fanfan;Huo Yong;Xu Xiping |
| 17 | China Stroke Primary Prevention Trial: Visit-to-Visit Systolic Blood Pressure Variability Is an Independent Predictor of Primary Stroke in Hypertensive Patients | 期刊论文 | Men Xi;Sun Wei;Fan Fangfang;Zhao Min;Huang Xiao;Wang Yu;Liu Lishun;Liu Ran;Sun Weiping;Peng Qing;Qin Xianhui;Tang Genfu;Li Jianping;Zhang Yan;Cai Yefeng;Hou Fan Fan;Wang Binyan;Xu Xiping;Cheng Xiaoshu;Sun Ningling;Huang Yining;Huo Yong |
| 18 | Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT). | 期刊论文 | Qin Xianhui;Li Youbao;He Mingli;Tang Genfu;Yin Delu;Liang Min;Wang Binyan;Nie Jing;Huo Yong;Xu Xin;Hou Fan Fan |
| 19 | Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China The CSPPT Randomized Clinical Trial | 期刊论文 | Huo Yong;Li Jianping;Qin Xianhui;Huang Yining;Wang Xiaobin;Gottesman Rebecca F.;Tang Genfu;Wang Binyan;Chen Dafang;He Mingli;Fu Jia;Cai Yefeng;Shi Xiuli;Zhang Yan;Cui Yimin;Sun Ningling;Li Xiaoying;Cheng Xiaoshu;Wang Jian'an;Yang Xinchun;Yang Tianlun;Xiao Chuanshi;Zhao Gang;Dong Qiang;Zhu Dingliang;Wang Xian;Ge Junbo;Zhao Lianyou;Hu Dayi;Liu Lisheng;Hou Fan Fan |
| 20 | Elevated Homocysteine Concentrations Decrease the Antihypertensive Effect of Angiotensin-Converting Enzyme Inhibitors in Hypertensive Patients. | 期刊论文 | Qin Xianhui;Li Youbao;Sun Ningling;Wang Hong;Zhang Yan;Wang Jiguang;Li Jianping;Xu Xin;Liang Min;Nie Jing;Wang Binyan;Cheng Xiaoshu;Li Nanfang;Sun Yingxian;Zhao Lianyou;Wang Xiaobin;Hou Fan Fan;Huo Yong |
| 21 | Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients. | 期刊论文 | Qin Xianhui;Li Jianping;Spence J David;Zhang Yan;Li Youbao;Wang Xiaobin;Wang Binyan;Sun Ningling;Chen Fang;Guo Jingxuan;Yin Delu;Sun Liming;Tang Genfu;He Mingli;Fu Jia;Cai Yefeng;Shi Xiuli;Ye Ping;Chen Hong;Zhao Shuiping;Chen Mao;Gao Chuanyu;Kong Xiangqing;Hou Fan Fan;Huang Yining;Huo Yong |
| 22 | Meta-analysis of folic acid efficacy trials in stroke prevention: insight into effect modifiers | 期刊论文 | Zhao Min;Wu Guangliang;Li Youbao;Wang Xiaobin;Hou Fan Fan;Xu Xiping;Qin Xianhui;Cai Yefeng |
| 23 | Effects of Folic Acid Therapy on the New-Onset Proteinuria in Chinese Hypertensive Patients A Post Hoc Analysis of the Renal Substudy of CSPPT (China Stroke Primary Prevention Trial) | 期刊论文 | Li Youbao;Liang Min;Wang Guobao;Wang Binyan;He Mingli;Tang Genfu;Yin Delu;Xu Xin;Huo Yong;Cui Yimin;Hou Fan Fan;Qin Xianhui |
| 24 | 中国脑卒中精准预防策略的转化应用 | 奖励 | 霍勇;李建平;徐希平;张岩;秦献辉;唐根福;何明利;陈光亮;刘平;王滨燕 |
| 25 | Proteinuria Is an Independent Risk Factor for First Incident Stroke in Adults Under Treatment for Hypertension in China | 期刊论文 | Zhang Chunyan;Wang Xiaobin;He Mingli;Qin Xianhui;Tang Genfu;Xu Xin;Wang Yu;Huo Yong;Cai Yefeng;Fu Jia;Zhao Gang;Dong Qiang;Xu Xiping;Wang Binyan;Hou Fan Fan |
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