脓毒症肝细胞中TET2DNA羟甲基化介导HMGB1胞质转位对巨噬细胞焦亡的调控及干预机制研究

U2004110
2020
孙同文
联合基金项目
主任医师
郑州大学
50万元
细胞焦亡;脓毒症;二甲双胍;高迁徙率族蛋白1;染色体10/11易位家族蛋白双加氧酶2
2021-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Efficacy and Safety of Corticosteroid Use in Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis 期刊论文 Yuqing Cui;Yali Sun;Junyi Sun;Huoyan Liang;Xianfei Ding;Xueyi Sun;Dong Wang;Tongwen Sun
2 Association Between Prior Calcium Channel Blocker Use and Mortality in Septic Patients: A Meta-Analysis of Cohort Studies 期刊论文 Xianfei Ding;Yuqing Cui;Huoyan Liang;Dong Wang;Lifeng Li;Quancheng Kan;Lexin Wang;Tongwen Sun
3 中国脓毒症十年研究回顾及展望 期刊论文 刘峰宇;李想;孙同文
4 成人全身播散性单纯疱疹病毒感染诊治经验 期刊论文 秦翠红;张曙光;赵颖颖;杨飞;孙同文
5 [The relationship between the lipid profiles and inflammation in patients with sepsis]. 期刊论文 Ya'nan Xu;Dong Wang;Huan Liu;Xianfei Ding;Xiaojuan Zhang;Shaohua Liu;Tongwen Sun
6 Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis 期刊论文 Xiaojuan Zhang;Yuqing Cui;Xianfei Ding;Shaohua Liu;Bing Han;Xiaoguang Duan;Haibo Zhang;Tongwen Sun
7 Classification of subtypes and identification of dysregulated genes in sepsis 期刊论文 Ran Tong;Xianfei Ding;Fengyu Liu;Hongyi Li;Huan Liu;Heng Song;Yuze Wang;Xiaojuan Zhang;Shaohua Liu;Tongwen Sun
8 一种脓毒血症诊断标志物 专利 孙同文;杨静华;刘欢;李弘毅;张蕾;薛新丽;杨永芳;朱庆庆
9 Clinical outcomes and safety of polymyxin B in the treatment of carbapenem-resistant Gram-negative bacterial infections: a real-world multicenter study 期刊论文 Zhang Xiaojuan;Qi Shaoyan;Duan Xiaoguang;Han Bing;Zhang Shuguang;Liu Shaohua;Wang Haixu;Zhang Haibo;Sun Tongwen
10 宏基因二代测序在肾综合征出血热重症患者中的诊断价值探讨 期刊论文 王海旭;赵颖颖;闫浩;付明森;王彩云;赵阳超;贠文晶;时学秀;孙同文
11 脓毒症心肌病的诊疗进展 期刊论文 刘峰宇;孙同文
12 Early intestinal microbiota changes in aged and adult mice with sepsis 期刊论文 Yangyang Yuan;Shaohua Liu;Xianfei Ding;Ying Li;Xiaojuan Zhang;Heng Song;Xueyan Qi;Zihao Zhang;Kaiyuan Guo;Tongwen Sun
13 西维来司他钠治疗脓毒症患者的有效性和安全性研究 期刊论文 祁雪颜;丁显飞;原阳阳;张晓娟;刘韶华;孙同文
14 Effects of Gabexate Mesylate on the Gut Microbiota and Metabolomics in Rats with Sepsis 期刊论文 Wenju Sun;Yuqing Cui;Xiaojuan Zhang;Yuze Wang;Zihao Zhang;Xianfei Ding;Huoyan Liang;Dong Wang;Yali Sun;Shaohua Liu;Xiaoguang Duan;Yibin Lu;Tongwen Sun
15 以脑梗死为首发表现的特鲁索综合征临床特征分析 期刊论文 时学秀;刘韶华;王岩;王海旭;赵颖颖;贠文晶;孙同文
16 Metformin Improves the Prognosis of Adult Mice with Sepsis-Associated Encephalopathy Better than That of Aged Mice 期刊论文 Gaofei Song;Huoyan Liang;Heng Song;Xianfei Ding;Dong Wang;Xiaojuan Zhang;Tongwen Sun
17 基于16S rDNA测序分析脓毒症大鼠早期肠道微生态的变化 期刊论文 李弘毅;翟瑞卿;梁火燕;朱彦辉;闫岩;王诚扬;丁显飞;宋高飞;孙同文
18 Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats 期刊论文 Yali Sun;Xianfei Ding;Yuqing Cui;Hongyi Li;Dong Wang;Huoyan Liang;Shaohua Liu;Xiaojuan Zhang;Haixu Wang;Tongwen Sun
19 甲磺酸加贝酯改善脓毒症急性肺损伤大鼠的代谢组学研究 期刊论文 王宁;丁显飞;崔玉青;孙亚丽;宋恒;孙俊一;宋高飞;原阳阳;孙同文
20 血必净注射液对脓毒症大鼠肠道菌群及其代谢组学的积极影响 期刊论文 丁显飞;原阳阳;仝然;王坤;刘韶华;祁雪颜;张晓娟;曹杰斌;孙同文
21 Corticosteroids for Treating Sepsis in Adult Patients: A Systematic Review and Meta-Analysis 期刊论文 Huoyan Liang;Heng Song;Ruiqing Zhai;Gaofei Song;Hongyi Li;Xianfei Ding;Quancheng Kan;Tongwen Sun
22 A purified membrane protein from Akkermansia muciniphila blunted the sepsis-induced acute lung injury by modulation of gut microbiota in rats 期刊论文 Bing Han;Ke Chao;Dong Wang;Yali Sun;Xianfei Ding;Xiaojuan Zhang;Shaohua Liu;Jiaxin Du;Yonggang Luo;Haixu Wang;Xiaoguang Duan;Huan Zhao;Tongwen Sun
23 Metformin attenuated sepsis-related liver injury by modulating gut microbiota 期刊论文 Huoyan Liang;Heng Song;Xiaojuan Zhang;Gaofei Song;Yuze Wang;Xianfei Ding;Xiaoguang Duan;Lifeng Li;Tongwen Sun;Quancheng Kan
24 Diagnosis of Mycobacterium tuberculosis Septic Shock in Patients With Anti-synthetase Syndrome Based on Next-Generation Sequencing: A Case Report and Literature Review 期刊论文 Limin Sun;Ziyue Yang;Fei Yang;Zhenhua Wang;Hongqiang Li;Huifen Wang;Tongwen Sun
25 Polymyxin B therapy based on therapeutic drug monitoring in carbapenem-resistant organisms sepsis: the PMB-CROS randomized clinical trial 期刊论文 Shaohua Liu;Ying Wu;Shaoyan Qi;Huanzhang Shao;Min Feng;Lihua Xing;Hongmei Liu;Yanqiu Gao;Zhiqiang Zhu;Shuguang Zhang;Yuming Du;Yibin Lu;Jing Yang;Pingyan Chen;Tongwen Sun
26 Identification of Prognostic Factors in Patients With Streptococcus Bloodstream Infection 期刊论文 Xiaoguang Duan;Ruifang Zhang;Xiaojuan Zhang;Xianfei Ding;Tongwen Sun
27 脓毒症定义变迁及病理机制研究进展 期刊论文 刘峰宇;孙同文
28 艾司洛尔对脓毒症休克患者预后的影响:随机对照研究的Meta分析 期刊论文 张瑞芳;刘欢;余言午;王岩;时学秀;张曙光;张子浩;孙同文
29 Adjunctive sepsis therapy with aminophylline (STAP): a randomized controlled trial 期刊论文 Zhang Ruifang;Liu Huan;Dai Dongmei;Ding Xianfei;Wang Dong;Wang Yan;Shi Xuexiu;Zhang Shuguang;Duan Xiaoguang;Wang Haixu;Luo Yonggang;Liu Shaohua;Han Bing;Zhang Xiaojuan;Fang Yu;Yang Jing;Xu Wangbin;Sun Tongwen
30 Efficacy and safety of low-dose corticosteroids for acute respiratory distress syndrome: A systematic review and meta-analysis 期刊论文 Cui Yuqing;Ding Xianfei;Liang Huoyan;Wang Dong;Zhang Xiaojuan;Li Lifeng;Kan Quancheng;Wang Lexin;Sun Tongwen
31 Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice 期刊论文 Heng Song;Xiaojuan Zhang;Ruiqing Zhai;Huoyan Liang;Gaofei Song;Yangyang Yuan;Yanan Xu;Yan Yan;Lingxiao Qiu;Tongwen Sun
32 Identification of metabolomics-based prognostic prediction models for ICU septic patients 期刊论文 Xianfei Ding;Ran Tong;Heng Song;Guiying Sun;Dong Wang;Huoyan Liang;Junyi Sun;Yuqing Cui;Xiaojuan Zhang;Shaohua Liu;Ming Cheng;Tongwen Sun
33 Association between intake of sweetened beverages with all-cause and cause-specific mortality: a systematic review and meta-analysis 期刊论文 Hongyi Li;Huoyan Liang;Han Yang;Xiaojuan Zhang;Xianfei Ding;Ruifang Zhang;Yimin Mao;Zhangsuo Liu;Quancheng Kan;Tongwen Sun
34 A Machine Learning Model for Accurate Prediction of Sepsis in ICU Patients 期刊论文 Dong Wang;Jinbo Li;Yali Sun;Xianfei Ding;Xiaojuan Zhang;Shaohua Liu;Bing Han;Haixu Wang;Xiaoguang Duan;Tongwen Sun
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