食管鳞癌组织免疫细胞亚群时空分布和靶向突变抗原的免疫干预研究
U1604286
2016
H1111.疫苗和免疫预防
高艳锋
联合基金项目
教授
郑州大学
215万元
食管鳞癌;突变抗原;免疫微环境;免疫治疗
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1 | 期刊论文 | Chen Zhenzhen;Liu Yating;Yao Lintong;Guo Shiying;Gao Yanfeng;Zhu Pingping |
| 2 | Young Peptide Scientist Award | 奖励 | 高艳锋 |
| 3 | The design of high affinity human PD-1 mutants by using molecular dynamics simulations (MD) | 期刊论文 | Jiangfeng Du;Yaping Qin;Yahong Wu;Wenshan Zhao;Wenjie Zhai;Yuanming Qi;Chuchu Wang;Yanfeng Gao |
| 4 | In vitro assay for the development of small molecule inhibitors targeting PD-1/PD-L1. | 期刊论文 | Zhai Wenjie;Zhou Xiuman;Du Jiangfeng;Gao Yanfeng |
| 5 | A Novel Recombinant Multi-Epitope Vaccine Could Induce Specific Cytotoxic T Lymphocyte Response In Vitro and In Vivo | 期刊论文 | Wu Yahong;Zhai Wenjie;Sun Meng;Zou Zhe;Zhou Xiuman;Li Guodong;Yan Zhongyi;Qi Yuanming;Gao Yanfeng |
| 6 | 河南省青年科技奖 | 奖励 | 高艳锋 |
| 7 | A novel D peptide identified by mirror-image phage display blocks TIGIT/PVR for cancer immunotherapy | 期刊论文 | Xiuman Zhou;Chao Zuo;Wanqiong Li;Weiwei Shi;Xiaowen Zhou;Hongfei Wang;Shaomeng Chen;Jiangfeng Du;Guanyu Chen;Wenjie Zhai;Wenshan Zhao;Yahong Wu;Yuanming Qi;Lei Liu;Yanfeng Gao |
| 8 | Sirpa蛋白亲和环肽及其应用 | 专利 | 高艳锋;李艳营;翟文杰;祁元明;王鸿飞 |
| 9 | POTN: A Human Leukocyte Antigen-A2 Immunogenic Peptides Screening Model and Its Applications in Tumor Antigens Prediction | 期刊论文 | Meng Qingqing;Wu Yahong;Sui Xinghua;Meng Jingjie;Wang Tingting;Lin Yan;Wang Zhiwei;Zhou Xiuman;Qi Yuanming;Du Jiangfeng;Gao Yanfeng |
| 10 | Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR | 期刊论文 | Zhou Xiuman;Du Jiangfeng;Wang Hongfei;Chen Chunxia;Jiao Ling;Cheng Xiangrui;Zhou Xiaowen;Chen Shaomeng;Gou Shanshan;Zhao Wenshan;Zhai Wenjie;Chen Junhui;Gao Yanfeng |
| 11 | PD-L1 IgV的亲和肽及其应用 | 专利 | 高艳锋;李琬琼;翟文杰;周秀曼;祁元明 |
| 12 | Characterization of CD103(+) CD8(+) tissue-resident T cells in esophageal squamous cell carcinoma: may be tumor reactive and resurrected by anti-PD-1 blockade | 期刊论文 | Han Lu;Gao Quanli;Zhou Xiuman;Shi Chao;Chen Guanyu;Song Yongping;Yao Yongjie;Zhao Yumiao;Wen Xueyan;Liu Shilei;Qi Yuanming;Gao Yanfeng |
| 13 | 一种人PD-1蛋白胞外段亲和环肽C8及其应用 | 专利 | 高艳锋;翟文杰;吴亚红;周秀曼 |
| 14 | CD47亲和肽及其应用 | 专利 | 高艳锋;王鸿飞;翟文杰;祁元明 |
| 15 | CD47/Sirpα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy. | 期刊论文 | Hongfei Wang;Yixuan Sun;Xiuman Zhou;Chunxia Chen;Ling Jiao;Wanqiong Li;Shanshan Gou;Yanying Li;Jiangfeng Du;Guanyu Chen;Wenjie Zhai;Yahong Wu;Yuanming Qi;Yanfeng Gao |
| 16 | 享受政府特殊津贴专家 | 奖励 | 高艳锋 |
| 17 | A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8(+) T cell responses | 期刊论文 | Zhai Wenjie;Zhou Xiuman;Wang Hongfei;Li Wanqiong;Chen Guanyu;Sui Xinghua;Li Guodong;Qi Yuanming;Gao Yanfeng |
| 18 | Blocking of the PD-1/PD-L1 interaction by a novel cyclic peptide inhibitor for cancer immunotherapy | 期刊论文 | Zhai Wenjie;Zhou Xiuman;Zhai Mingxia;Li Wanqiong;Ran Yunhui;Sun Yixuan;Du Jiangfeng;Zhao Wenshan;Xing Lingxiao;Qi Yuanming;Gao Yanfeng |
| 19 | Intrinsic Expression of Immune Checkpoint Molecule TIGIT Could Help Tumor Growth in vivo by Suppressing the Function of NK and CD8(+) T Cells | 期刊论文 | Zhou Xiuman;Li Wanqiong;Wu Yahong;Han Lu;Cao Xinguang;Yang Xuanming;Wang Hongfei;Zhao Wenshan;Zhai Wenjie;Qi Yuanming;Gao Yanfeng |
| 20 | HLA-A2-Restricted Epitopes Identified from MTA1 Could Elicit Antigen-Specific Cytotoxic T Lymphocyte Response | 期刊论文 | Yahong Wu;Wenjie Zhai;Xiuman Zhou;Zhiwei Wang;Yan Lin;Ling Ran;Yuanming Qi;Yanfeng Gao |
| 21 | TIGIT-IgV的亲和剂及其应用 | 专利 | 高艳锋;周秀曼;李琬琼;翟文杰;吴亚红;赵文珊;祁元明 |
| 22 | 一种亲和PD-1的肽及其应用 | 专利 | 高艳锋;冉云慧;翟文杰;祁元明 |
| 23 | 百千万人才工程国家级人选/国家有突出贡献中青年专家 | 奖励 | 高艳锋 |
| 24 | Computer-aided design of PVR mutants with enhanced binding affinity to TIGIT | 期刊论文 | Xiaowen Zhou;Jiangfeng Du;Xiuman Zhou;Xiaoshuang Niu;Wanqiong Li;Chunxia Chen;Sifan Lv;Aijun Wu;Shanshan Gou;Yixuan Sun;Wenjie Zhai;Lu Qiu;Yuanming Qi;Wenshan Zhao;Yanfeng Gao |
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