具有GLUT1主动转运、葡萄糖和RGD肽双重肿瘤识别的脑靶向脂质体的制备及其在耐药脑肿瘤的应用研究

81903448
2019
H3401.合成药物化学
赵毅
青年科学基金项目
助理研究员
郑州大学
21万元
葡萄糖;耐药脑肿瘤;脑靶向脂质体;RGD肽;P-糖蛋白
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 儿童颅内非典型畸胎样/横纹肌样瘤的诊治及预后分析 期刊论文 王蒙;赵毅;赵培超;张鹏;潘圆圆;李天豪;刘学友;王泽明;邱成茗;张仁德;孙红卫
2 Multiple targeted doxorubicin-lonidamine liposomes modified with p-hydroxybenzoic acid and triphenylphosphonium to synergistically treat glioma 期刊论文 Jiaqi Lu;Ru Li;Binsong Mu;Yao Peng;Yi Zhao;Yuesen Shi;Li Guo;Li Hai;Yong Wu
3 Synthesis and preliminary biological evaluation of Naproxen-Probenecid conjugate for central nervous system (CNS) delivery 期刊论文 Bo Jiang;Yi Zhao;Junhan Cao;Yang Yang;Tao Kuang;Qi Zhang;Xiaoqun Liu;Xi Chen;Xin Liu;Xiaolin Liao;Xiaoli Zhou;Zengtao Xu
4 Dual-targeting liposome modified by glutamic hexapeptide and folic acid for bone metastatic breast cancer 期刊论文 Yang Yang;Ze Zhao;Changwei Xie;Yi Zhao
5 Glucose and Triphenylphosphonium Co-Modified Redox-Sensitive Liposomes to Synergistically Treat Glioma with Doxorubicin and Lonidamine 期刊论文 Yao Peng;Jiaqi Lu;Ru Li;Yi Zhao;Li Hai;Li Guo;Yong Wu
6 Recent advances in drug delivery systems for targeting brain tumors 期刊论文 Yi Zhao;Ping Yue;Yao Peng;Yuanyuan Sun;Xing Chen;Ze Zhao
7 神经导航辅助下穿刺抽吸治疗儿童脑脓肿的疗效及预后因素分析 期刊论文 王蒙;赵毅;赵培超;张鹏;潘圆圆;李天豪;刘学友;王泽明;邱成茗;张仁德;孙红卫
8 Design, synthesis and evaluation of liposomes modified with dendritic aspartic acid for bone-specific targeting 期刊论文 Ze Zhao;Changqing Chen;Changwei Xie;Yi Zhao
9 Synthesis and evaluation of novel bone-targeting ibuprofen prodrug based on dendritic aspartic acid 期刊论文 Yi Zhao;Ze Zhao;Yamin Cui;Changqing Chen;Changwei Xie;Yang Yang
10 Design, Preparation and Evaluation of Different Branched Biotin Modified Liposomes for Targeting Breast Cancer 期刊论文 Baolan Tang;Yao Peng;Qiming Yue;Yanchi Pu;Ru Li;Yi Zhao;Li Hai;Li Guo;Yong Wu
11 Fructose and biotin co-modified liposomes for dual-targeting breast cancer 期刊论文 Ru Li;Yao Peng;Yanchi Pu;Yi Zhao;Ruifang Nie;Li Guo;Yong Wu
12 Redox-responsive glycosylated combretastatin A-4 derivative as novel tubulin polymerization inhibitor for glioma and drug delivery 期刊论文 Yi Zhao;Ze Zhao;Yamin Cui;Xing Chen;Changqing Chen;Changwei Xie;Bo Qin;Yang Yang
13 pH-redox responsive cascade-targeted liposomes to intelligently deliver doxorubicin prodrugs and lonidamine for glioma 期刊论文 Yi Zhao;Yao Peng;Zhongzhen Yang;Jiaqi Lu;Ru Li;Yuesen Shi;Yaxin Du;Ze Zhao;Li Hai;Yong Wu
14 Glioma exosomal microRNA-148a-3p promotes tumor angiogenesis through activating the EGFR/MAPK signaling pathway via inhibiting ERRFI1 期刊论文 Meng Wang;Yi Zhao;Zhi-Yun Yu;Ren-De Zhang;Shu-Ang Li;Peng Zhang;Ti-Kun Shan;Xue-You Liu;Ze-Ming Wang;Pei-Chao Zhao;Hong-Wei Sun
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