构建α-突触核蛋白异构体诱导食蟹猴多系统萎缩模型及相关机制研究

81671267
2016
H0912.神经退行性变及相关疾病
滕军放
面上项目
主任医师
郑州大学
75万元
动物模型;核;多系统萎缩;自主神经系统;α-突触核蛋白;Onuf
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Intranasal Administration of GDNF Protects Against Neural Apoptosis in a Rat Model of Parkinson's Disease Through PI3K/Akt/GSK3beta Pathway 期刊论文 Peijian Yue;Lin Gao;Xuejing Wang;Xuebing Ding;Junfang Teng
2 Pretreatment of glial cell-derived neurotrophic factor and geranylgeranylacetone ameliorates brain injury in Parkinson's disease by its anti-apoptotic and anti-oxidative property 期刊论文 Peijian Yue;Lin Gao;Xuejing Wang;Xuebing Ding;Junfang Teng
3 Propagation of Pathological α-Synuclein from the Urogenital Tract to the Brain Initiates MSA-like Syndrome 期刊论文 Ding X Zhou L Jiang X Liu H Yao J Zhang R Liang D Wang F Ma M Tang B Wu E Teng J;Wang X
4 Ultrasound-triggered effects of the microbubbles coupled to GDNF- and Nurr1-loaded PEGylated liposomes in a rat model of Parkinson's disease 期刊论文 Peijian Yue;Lin Gao;Xuejing Wang;Xuebing Ding;Junfang Teng
5 Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson's disease 期刊论文 Ding XB Wang XX;Wang XJ
6 Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy 期刊论文 Wang XJ Ma MM Zhou LB Jiang XY Hao MM Teng RKF Wu E Tang BS Li JY Teng JF;Ding XB
7 miR-124 promotes proliferation and neural differentiation of neural stem cells through targeting DACT1 and activating Wnt_β-catenin pathways 期刊论文 Shujie Jiao;Yaling Liu;Yaobing Yao;Junfang Teng
8 Long noncoding MIAT acting as a ceRNA to sponge microRNA-204-5p to participate in cerebral microvascular endothelial cell injury after cerebral ischemia through regulating HMGB1 期刊论文 Deng W Fan C Shen R Wu Y Du R;Teng J
9 Role of XIAP gene overexpressed bone marrow mesenchymal stem cells in the treatment of cerebral injury in rats with cerebral palsy 期刊论文 Deng W Fan C Fang Y Zhao Y Wei Y Li M;Teng J
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