BAG5/Hsp70复合体调控外泌体及隧道纳米管介导的TDP-43阳性包涵体在神经元与星形胶质细胞间转运

81471307
2014
H0912.神经退行性变及相关疾病
王雪晶
面上项目
副教授
郑州大学
70万元
热休克蛋白70;TAR;BAG5;隧道纳米管;DNA结合蛋白43;外泌体
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Exposure to ALS-FTD-CSF generates TDP-43 aggregates in glioblastoma cells through exosomes and TNTs-like structure. 期刊论文 Ding Xuebing;Ma Mingming;Teng Junfang;Teng Robert K F;Zhou Shuang;Yin Jingzheng;Fonkem Ekokobe;Huang Jason H;Wu Erxi;Wang Xuejing
2 Numb induces e-cadherin adhesion dissolution, cytoskeleton reorganization, and migration in tubular epithelial cells contributing to renal fibrosis 期刊论文 Xuebing Ding;Mingming Ma;Junfang Teng;Fengmin Shao;Robert K.F. Teng;Shuang Zhou;Ying Zhang;Erxi Wu;Xuejing Wang
3 Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation. 期刊论文 Wang Xuejing;Zhou Shuang;Ding Xuebing;Ma Mingming;Zhang Jiewen;Zhou Yue;Wu Erxi;Teng Junfang
4 Valproate Attenuates 25-kDa C-terminal Fragment of TDP-43- induced Neuronal Toxicity Via Suppressing Endoplasmic Reticulum Stress And Activating Autophagy 期刊论文 Xuejing Wang;Mingming Ma;Junfang Teng;Wenwen Zhang;Fengfei Wang Xiangqian Che;Shuang Zhou;Ying Zhang;Erxi Wu;Xuebing Ding
5 Pretreatment of glial cell-derived neurotrophic factor and geranylgeranylacetone ameliorates brain injury in Parkinson's disease by its anti-apoptotic and anti-oxidative property 期刊论文 Yue P;Gao L;Wang X;Ding X;Teng J
6 Numb Protects Human Renal Tubular Epithelial Cells From Bovine Serum Albumin-Induced Apoptosis Through Antagonizing CHOP/PERK Pathway 期刊论文 Xuebing Ding;Mingming Ma;Junfang Teng;Fengmin Shao;Erxi Wu;Xuejing Wang
7 Intranasal Administration of GDNF Protects Against Neural Apoptosis in a Rat Model of Parkinson's Disease Through PI3K/Akt/GSK3β Pathway 期刊论文 Yue P;Gao L;Wang X;Ding X;Teng J
8 Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation. 期刊论文 Wang Xuejing;Ma Mingming;Teng Junfang;Zhang Jiewen;Zhou Shuang;Zhang Ying;Wu Erxi;Ding Xuebing
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