【81170630】VitA和TGFβ在腭裂诱发中的相互作用及机制国家自然基金项目

VitA和TGFβ在腭裂诱发中的相互作用及机制

项目批准号： 81170630

批准年份： 2011

学科分类： H0422.生殖系统/围生医学/新生儿疾病研究新技术与新方法

项目负责人：余增丽

资助类别：面上项目

负责人职称：教授

依托单位：郑州大学

资助金额： 65万元

关键词： VitA;TGIF;TGFβ;腭裂

起止时间： 2012-01-01到2015-12-31

中英文摘要
结题摘要
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序号	标题	类型	作者
1	妊早期妇女血清叶酸水平与胎儿出生缺陷发病关系的队列研究	期刊论文	王珊\|潘新娟\|余增丽\|
2	Excessive retinoic acid impaired proliferation and differentiation of human fetal palatal chondrocytes (hFPCs).	期刊论文	Pan, Xinjuan\|Liu, Xiaozhuan\|Li, Xing\|Yu, Zengli\|
3	Negative functional interaction of Retinoic Acid and TGF-β signaling mediated by TG-interacting factor during chondrogenesis	期刊论文	Zhang Hang\|Li Ning\|Tang Yunan\|Zhang Qi\|Yu Zengli\|
4	Negative interplay of retinoic acid and TGF-beta signaling mediated by TG-interacting factor to modulate mouse embryonic palate mesenchymal-cell proliferation.	期刊论文	Li, Zhitao\|Li, Ning\|Li, Haozhe\|Yu, Zengli\|
5	食品安全	专著
6	Retinoic acid remodels extracellular matrix (ECM) of cultured human fetal palate mesenchymal cells (hFPMCs) through down- regulation of TGF-beta/Smad signaling	期刊论文	Liu, Xiaozhuan\|Pan, Xinjuan\|Li, Ning\|Yu, Zengli\|
7	开封市出生缺陷影响因素病例对照研究	期刊论文	王珊\|潘新娟\|余增丽\|
8	妊早期妇女血清叶酸水平与胎儿出生缺陷发病关系的队列研究	期刊论文	王珊\|潘新娟\|余增丽\|
9	The Effects of Early Life Lead Exposure on the Expression of Glycogen Synthase Kinase-3beta and Insulin-like Growth Factor 1 Receptor in the Hippocampus of Mouse Pups.	期刊论文	Zhang, PingAn\|Li, Xing\|Li, Li\|Yu, ZengLi\|
10	葡萄籽提取物改善砷暴露致大鼠肝损伤的作用及机制	期刊论文	潘新娟\|李星\|代玉洁\|余增丽\|
11	河南省2007年至2010年高龄产妇围产儿出生缺陷分析	期刊论文	孙利环\|有风芝\|胡孟彩\|余增丽\|
12	Inhibition of arsenic-induced rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF-beta/Smad activation.	期刊论文	Li, Wenjie\|Liu, Fangli\|Zhao, Yang\|Yu, Zengli\|
13	Excessive Retinoic Acid Impaired Proliferation and Differentiation of Human Fetal Palatal Chondrocytes (hFPCs)	期刊论文	Pan, Xinjuan\|Liu, Xiaozhuan\|Li, Xing\|Yu, Zengli\|
14	视黄酸经TGF-beta3信号途径诱发腭裂的生物学机制	奖励
15	Inhibition of arsenic-induced rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF-beta/Smad activation.	期刊论文	Li, Wenjie\|Liu, Fangli\|Zhao, Yang\|Yu, Zengli\|
16	Association between Maternal MTHFR Polymorphisms and Nonsyndromic CleftLip with or without Cleft Palate in Offspring, A Meta-Analysis Based on 15Case-Control Studies	期刊论文	Pan X, Wang P, Yin X, Liu X, Li D, Li X, Wang Y, Li H, Yu Z*\|
17	Association between Environmental Dioxin-Related Toxicants Exposure andAdverse Pregnancy Outcome: Systematic Review and Meta-Analysis	期刊论文	Pan X, Wang P, Yin X, Liu X, Li D, Li X, Wang Y, Li H, Yu Z*.\|
18	The effects of early life lead exposure on the expression of insulin-like growth factor 1 and 2 (IGF1, IGF2) in the hippocampus of mouse pups.	期刊论文	Liu, Xiaozhuan\|Li, Haozhe\|Li, Xing\|Yu, Zengli\|
19	Inhibition of Smad signaling is implicated in cleft palate induced by all-trans retinoic acid.	期刊论文	Li, Xing\|Chen, Can Ying\|Li, Wenjie\|Yu, Zengli\|
20	Retinoic acid remodels extracellular matrix (ECM) of cultured human fetal palate mesenchymal cells (hFPMCs) through down-regulation of TGF-beta/Smad signaling.	期刊论文	Liu, Xiaozhuan\|Pan, Xinjuan\|Li, Ning\|Yu, Zengli\|
21	过量全反式视黄酸对腭突中嵴上皮细胞迁移的影响	期刊论文	代玉洁\|赵长海\|牛楠楠\|潘新娟\|余增丽\|
22	INHIBITION OF SMAD SIGNALING IS IMPLICATED IN CLEFT PALATE INDUCED BY ALL-TRANS RETINOIC ACID	期刊论文	Li, Xing\|Chen, Can Ying\|Li, Wenjie\|Yu, Zengli\|
23	Grape seed extract attenuates arsenic-induced nephrotoxicity in rats	期刊论文	Wang, Yongchao\|Liu, Xiaozhuan\|Yin, Xinjuan\|Yu, Zengli\|
24	Grape seed extract attenuates arsenic-induced nephrotoxicity in rats.	期刊论文	Wang, Yongchao\|Liu, Xiaozhuan\|Yin, Xinjuan\|Yu, Zengli\|
25	The effects of early life lead exposure on the expression of insulin-like growth factor 1 and 2 (IGF1, IGF2) in the hippocampus of mouse pups	期刊论文	Liu, Xiaozhuan\|Li, Haozhe\|Li, Xing\|Yu, Zengli\|
26	河南省2007年至2010年高龄产妇围产儿出生缺陷分析	期刊论文	孙利环\|有风芝\|胡孟彩\|余增丽\|

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