拟除虫菊酯类杀虫剂与遗传因素的相互作用在新疆地区帕金森病发病中的效应及机制研究
U1603281
2016
H2001.康复治疗与康复机制
瞿少刚
联合基金项目
教授
南方医科大学
265万元
易感基因;免疫失调;帕金森病;表观遗传学;环境因素
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Association of DNMT3b gene variants with sporadic Parkinson's disease in a Chinese Han population | 期刊论文 | Xiang Che;Yousheng Xiao;Lei Wei;Yijuan Wu;Jianjun Lu;Wenyuan Guo;Shuxuan Huang;Miaomiao Zhou;Mingshu Mo;Zhe Li;Luan Cen;Shaomin Li;ChaohaoYang;Zhuohua Wu;Sophie Hu;Zhong Pei;XinLing Yang;Shaogang Qu;Pingyi Xu |
| 2 | Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system | 期刊论文 | Zhigang Jiao;Yixuan Wu;Shaogang Qu |
| 3 | Glutamate, Glutamate Transporters, and Circadian Rhythm Sleep Disorders in Neurodegenerative Diseases | 期刊论文 | Suifen He;Xiuping Zhang;Shaogang Qu |
| 4 | Substrate-Induced Motion between TM4 and TM7 of the Glutamate Transporter EAAT1 Revealed by Paired Cysteine Mutagenesis | 期刊论文 | Wenlong Zhang;Xiuping Zhang;Shaogang Qu |
| 5 | Astrocytic glutamatergic transporters are involved in Aβ-induced synaptic dysfunction | 期刊论文 | Shuxuan Huang;Huichun Tong;Ming Lei;Miaomiao Zhou;Wenyuan Guo;Guihua Li;Xiaolu Tang;Zhe Li;Mingshu Mo;Xiuping Zhang;Xiang Chen;Luan Cen;Lei Wei;Yousheng Xiao;Kaiping Li;Qinghui Huang;Xinling Yang;Weiguo Liu;Li Zhang;Shaogang Qu;Shaomin Li;Pingyi Xu |
| 6 | Paired-cysteine scanning reveals conformationally sensitive proximity between the TM4b-4c loop and transmembrane domain 8 of the glutamate transporter EAAT1 | 期刊论文 | Shaogang Qu;Wenlong Zhang;Suifen He;Xiuping Zhang |
| 7 | Pretreatment of Ascorbic Acid Inhibits MPTP-Induced Astrocytic Oxidative Stress through Suppressing NF- κ B Signaling | 期刊论文 | Xiaokang Zeng;Kai Xu;Ji Wang;Yunqi Xu;Shaogang Qu |
| 8 | Generation of a novel mouse model of Parkinson's disease via targeted knockdown of glutamate transporter GLT-1 in the substantia nigra | 期刊论文 | Yunlong Zhang;Xingjun Meng;Shaogang Qu;Zhigang Jiao;Yan Liu;Xiuping Zhang;Shaogang Qu |
| 9 | 5Z-7-oxozeaenol在制备治疗自身免疫性脑脊髓炎药物中的应用 | 专利 | 瞿少刚;陆伶俐;张秀萍;童辉纯;孟行军;麦东媚 |
| 10 | Cysteine Scanning Mutagenesis of TM4b-4c Loop of Glutamate Transporter EAAT1 Reveals Three Conformationally Sensitive Residues | 期刊论文 | Wenlong Zhang;Xiuping Zhang;Shaogang Qu |
| 11 | Gene Dysfunction Mediates Immune Response to Dopaminergic Degeneration in Parkinson’s Disease | 期刊论文 | Zhigang Jiao;Wenlong Zhang;Chaojun Chen;Xiaoqin Zhu;Xiang Chen;Miaomiao Zhou;Guoyou Peng;Hanqun Liu;Jiewen Qiu;Yuwan Lin;Shuxuan Huang;Mingshu Mo;Xinling Yang;Shaogang Qu;Pingyi Xu |
| 12 | Rapamycin upregulates glutamate transporter andIL-6 expression in astrocytes in a mouse model of Parkinson’s disease | 期刊论文 | Yunlong Zhang;Xiaoliang He;Xiaojuan Wu;Ming Lei;Zhiyun Wei;Xiuping Zhang;Lei Wen;Pingyi Xu;Shaomin Li;Shaogang Qu |
| 13 | Amyloid-beta peptide decreases expression and function of glutamate transporters in nervoussystem cells | 期刊论文 | Huichun Tong;Xiuping Zhang;Xingjun Meng;Pingyi Xu;Xiaoming Zou;Shaogang Qu |
| 14 | Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway | 期刊论文 | Shaogang Qu;Xingjun Meng;Yan Liu;Xiuping Zhang;Yunlong Zhang |
| 15 | Peripheral Lymphocyte Subsets as a Marker of Parkinson's Disease in a Chinese Population | 期刊论文 | Luan Cen;Chaohao Yang;Shuxuan Huang;Miaomiao Zhou;Xiaolu Tang;Kaiping Li;Wenyuan Guo;Zhuohua Wu;Mingshu Mo;Yousheng Xiao;Xiang Chen;Xinling Yang;Qinhui Huang;Chaojun Chen;Shaogang Qu;Pingyi Xu |
| 16 | Regulatory Mechanism of miR-543-3p on GLT-1 in a Mouse Model of Parkinson's Disease | 期刊论文 | Xiaojuan Wu;Xingjun Meng;Feng Tan;Zhigang Jiao;Xiuping Zhang;Huichun Tong;Xiaoliang He;Xiaodong Luo;Pingyi Xu;Shaogang Qu |
| 17 | Central administration of 5Z-7-oxozeaenol protects experimental autoimmune encephalomyelitis mice by inhibiting microglia activation | 期刊论文 | Lingli Lu;Xiuping Zhang;Huichun Tong;Wenlong Zhang;Pingyi Xu;Shaogang Qu |
| 18 | Regulation of glutamate transporter trafficking by Nedd4-2 in a Parkinson’s disease model | 期刊论文 | Yunlong Zhang;Xiaoliang He;Xingjun Meng;Xiaojuan Wu;Huichun Tong;Xiuping Zhang;Shaogang Qu |
| 19 | Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo | 期刊论文 | Ming-Shu Mo;Gui-Hua Li;Cong-Cong Sun;Shu-Xuan Huang;Lei Wei;Li-Min Zhang;Miao-Miao Zhou;Zhuo-Hua Wu;Wen-Yuan Guo;Xin-Ling Yang;Chao-Jun Chen;Shao-Gang Qu;Jian-Xing He;Ping-Yi Xu |
| 20 | Simvastatin Inhibits Activation of NADPH Oxidase/p38 MAPK Pathway and Enhances Expression of Antioxidant Protein in Parkinson Disease Models | 期刊论文 | Huichun Tong;Xiuping Zhang;Xingjun Meng;Lingli Lu;Dongmei Mai;Shaogang Qu |
| 21 | Iron promotes α-synuclein aggregation and transmission by inhibiting TFEB-mediated autophagosome-lysosome fusion. | 期刊论文 | Yousheng Xiao;Xiang Chen;Shuxuan Huang;Guihua Li;Mingshu Mo;Li Zhang;Chaojun Chen;Wenyuan Guo;Miaomiao Zhou;Zhuohua Wu;Luan Cen;Simei Long;Shaomin Li;Xinling Yang;Shaogang Qu;Zhong Pei;Pingyi Xu |
| 22 | 科学技术奖励证书 | 奖励 | 瞿少刚 |
查看更多信息请先登录或注册
