天然药物靶标发现的化学蛋白质组学新技术

81703471
2017
H3410.药物分析
郑秋凌
青年科学基金项目
副教授
中国药科大学
21万元
蛋白质组学;天然药物靶标发现;非变性质谱;解吸附电喷雾电离源;在线酶切辅助结构解析
2018-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Prediction of fibril formation by early-stage amyloid peptide aggregation 期刊论文 Hu Jiaojiao;Sun Huiyong;Hao Haiping;Zheng Qiuling
2 Probing specific ligand-protein interactions by native-denatured exchange mass spectrometry 期刊论文 Zheng Qiuling;Tian Yang;Ruan Xujun;Chen Hao;Wu Xunxun;Xu Xiaowei;Wang Guangji;Hao Haiping;Ye Hui
3 Ligand-protein target screening from cell matrices using reactive desorption electrospray ionization-mass spectrometry via a native-denatured exchange approach 期刊论文 Zheng Qiuling;Ruan Xujun;Tian Yang;Hu Jiaojiao;Wan Ning;Lu Wenjie;Xu Xiaowei;Wang Guangji;Hao Haiping;Ye Hui
4 An improved detection and identification strategy for untargeted metabolomics based on UPLC-MS 期刊论文 Hou Yuanlong;He Dandan;Ye Ling;Wang Guangji;Zheng Qiuling;Hao Haiping
5 Boronic Derivatization of Monoacylglycerol and Monitoring in Biofluids 期刊论文 Zhu Mengle;Xu Xiaowei;Hou Yuanlong;Han Jialing;Wang Jin;Zheng Qiuling;Hao Haiping
6 Drug target discovery by magnetic nanoparticles coupled mass spectrometry 期刊论文 Xia Dandan;Liu Baoling;Xu Xiaowei;Ding Ya;Zheng Qiuling
7 Applications of mass spectrometry in the onset of amyloid fibril formation: focus on the analysis of early-stage oligomers 期刊论文 Hu Jiaojiao;Zheng Qiuling
8 氘代-3-硝基苯硼酸及其制备方法与应用 专利 郝海平;徐小为;郑秋凌;朱梦乐;韩佳玲
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