基于深部肿瘤渗透的新策略高效构建肿瘤靶向治疗的仿生纳米细胞传递系统

81671803
2016
H2809.医用生物材料与仿生材料
陈海燕
面上项目
教授
中国药科大学
56万元
抗肿瘤血管生成;肿瘤深部治疗;免疫逃逸;溶酶体逃逸;纳米细胞
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Design and synthesis of NQO1 responsive fluorescence probe and its application in bio-imaging for cancer diagnosis 期刊论文 Yuan Zhenwei;Xu Mingjun;Wu Tianze;Zhang Xinyi;Shen Yuanzhi;Ernest Umeorah;Gui Lijuan;Wang Fei;He Qing;Chen Haiyan
2 GSH-Activated Light-Up Near-Infrared Fluorescent Probe with High Affinity to αvβ3 Integrin for Precise Early Tumor Identification 期刊论文 Zhenwei Yuan;Lijuan Gui;Jinrong Zheng;Yisha Chen;Sisi Qu;Yuanzhi Shen;Fei Wang;Murat Er;Yueqing Gu;Haiyan Chen
3 Development of photosensitizer-loaded lipid droplets for photothermal therapy based on thiophene analogs 期刊论文 Yue Xu;Hua Li;Lixue Fan;Yisha Chen;Li Li;Xiaojing Zhou;Ruixi Li;Yuru Cheng;Haiyan Chen;Zhenwei Yuan
4 A visible and near-infrared, dual emission fluorescent probe based on thiol reactivity for selectively tracking mitochondrial glutathione in vitro 期刊论文 Xu Yue;Li Ruixi;Zhou Xiaojing;Li Weiqing;Ernest Umeorah;Wan Hao;Li Li;Chen Haiyan;Yuan Zhenwei
5 Thermosensitive drug-loading system based on copper sulfide nanoparticles for combined photothermal therapy and chemotherapy in vivo 期刊论文 Zhenwei Yuan;Sisi Qu;Yuanyuan He;Yue Xu;Li Liang;Xiaojing Zhou;Lijuan Gui;Yuqing Gu;Haiyan Chen
6 Near-infrared off-on fluorescence probe activated by NTR for in vivo hypoxia imaging 期刊论文 Zheng Jinrong;Shen Yuanzhi;Xu Zhiqiang;Yuan Zhenwei;He Yuanyuan;Wei Chen;Er Murat;Yin Jun;Chen Haiyan
7 A family of push-pull bio-probes for tracking lipid droplets in living cells with the detection of heterogeneity and polarity. 期刊论文 Li L;Xu Y;Chen Y;Zheng J;Zhang J;Li R;Wan H;Yin J;Yuan Z;Chen H
8 Biocompatible CuS-based nanoplatforms for efficient photothermal therapy and chemotherapy in vivo 期刊论文 Shuwen Peng;Yuanyuan He;Murat Er;Yuanzhi Sheng;Yueqing Gu;Haiyan Chen
9 Near-Infrared-Light-Responsive Lipid Nanoparticles as an Intelligent Drug Release System for Cancer Therapy 期刊论文 Wang Fei;Yuan Zhenwei;McMullen Patrick;Li Ruixi;Zheng Jinrong;Xu Yue;Xu Mingjun;He Qing;Li Bowen;Chen Haiyan
10 A tumor-targeting probe based on a mitophagy process for live imaging 期刊论文 Gui Lijuan;Yuan Zhenwei;Kassaye Habtamu;Zheng Jinrong;Yao Yuxin;Wang Fei;He Qing;Shen Yuanzhi;Liang Li;Chen Haiyan
11 A new lysosome-targetable fluorescent probe for detection of endogenous hydrogen polysulfides in living cells and inflamed mouse model. 期刊论文 Liang L;Li W;Zheng J;Li R;Chen H;Yuan Z
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