CysLT1R在阿尔茨海默病中的作用及机制研究

81573413
2015
H3501.神经精神药物药理
洪浩
面上项目
教授
中国药科大学
62万元
阿尔茨海默病;半胱氨酰白三烯受体1;β淀粉样蛋白
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Mogrol attenuates lipopolysaccharide (LPS)-induced memory impairment and neuroinflammatory responses in mice 期刊论文 Wang Hui;Meng Guo Liang;Zhang Chun Teng;Wang Hao;Hu Mei;Long Yan;Hong Hao;Tang Su Su
2 Zileuton ameliorates depressive-like behaviors, hippocampal neuroinflammation, apoptosis and synapse dysfunction in mice exposed to chronic mild stress 期刊论文 Cai-Hong Liu;Yuan-Zhi Tan;Dan-Dan Li;Su-Su Tang;Xiao-An Wen;Yan Long;Hong-Bin Sun;Hao Hong;Mei Hu
3 CysLT(1)R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice 期刊论文 Ghosh Arijit;Chen Fang;Wu Feng;Tang Su Su;Hu Mei;Long Yan;Sun Hong Bin;Kong Ling Yi;Hong Hao
4 Preventive effect of genetic knockdown and pharmacological blockade of CysLT(1)R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo 期刊论文 Chen Fang;Ghosh Arijit;Wu Feng;Tang Susu;Hu Mei;Sun Hongbin;Kong Lingyi;Hong Hao
5 Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice 期刊论文 Wang Hao;Chen Fang;Du Yi-Feng;Long Y;Suppiramaniam V;Hu M;Reed MN;Hong Hao;Tang SS
6 Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice 期刊论文 Wu Xian;Lv Yang Ge;Du Yi Feng;Hu Mei;Reed Miranda N;Long Yan;Suppiramaniam Vishnu;Hong Hao;Tang Su Su
7 Hippocampal CysLT(1)R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice 期刊论文 Lin Jing ran;Fang Shun chang;Tang Su su;Hu Mei;Long Yan;Ghosh Arijit;Sun Hong bin;Kong Ling yi;Hong Hao
8 Neuroprotective effects of INT-777 against Aβ1-42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice. 期刊论文 Xian Wu;Yang-Ge Lv;Yi-Feng Du;Fang Chen;Miranda N. Reed;Mei Hu;Vishnu Suppiramaniam;Su-Su Tang;Hao Hong
9 SIMVASTATIN AMELIORATES MEMORY IMPAIRMENT AND NEUROTOXICITY IN STREPTOZOTOCIN-INDUCED DIABETIC MICE 期刊论文 Fang Shun Chang;Xie Hang;Chen Fang;Hu Mei;Long Yan;Sun Hong Bin;Kong Ling Yi;Hong Hao;Tang Su Su
10 Pharmacology 专著 朱依谆;殷明;陈忠;魏敏杰;刘叔文;洪浩;等
11 Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice 期刊论文 Dan-Dan Li;Hang Xie;Yi-Feng Du;Yan Long;Miranda N.Reed;Mei Hu;Vishnu Suppiramaniam;Hao Hong;Su-Su Tang
12 ER alpha and/or ER beta activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice 期刊论文 Tang Su Su;Ren Yi;Ren Xiao Qian;Cao Jing Ran;Hong Hao;Ji Hui;Hu Qing Hua
13 1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis 期刊论文 Rong-haoMu;Yuan-zhiTan;Li-liFu;MohammadNazmul Islam;MeiHu;HaoHong;Su-suTang
14 Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice 期刊论文 Wu Xian;Liu Caihong;Chen Liang;Du Yi Feng;Hu Mei;Reed Miranda N;Long Yan;Suppiramaniam Vishnu;Hong Hao;Tang Su Su
15 Neuroprotective effect of mogrol against A beta(1-42)-induced memory impairment neuroinflammation and apoptosis in mice 期刊论文 Chen Gangling;Liu Caihong;Meng Guoliang;Zhang Chunteng;Chen Fang;Tang Susu;Hong Hao;Zhang Chaofeng
16 Cysteinyl Leukotrienes and Their Receptors: Emerging Therapeutic Targets in Central Nervous System Disorders 期刊论文 Ghosh Arijit;Chen Fang;Thakur Abhimanyu;Hong Hao
17 Hippocampal Genetic Knockdown of PPARδ Causes Depression-Like Behaviors and Neurogenesis Suppression 期刊论文 Fang Chen;Xuben Yu;Guoliang Meng;Zhenlin Mei;Yifeng Du;Hongbin Sun;Miranda N Reed;Lingyi Kong;Vishnu Suppiramaniam;Hao Hong;Susu Tang
18 药理学题库 专著 洪浩;邹莉波;杜俊蓉;张雪梅;钱峰;等
19 Protective Effects of 1-Methylnicotinamide on A beta(1-42)-Induced Cognitive Deficits, Neuroinflammation and Apoptosis in Mice 期刊论文 Fu Lili;Liu Caihong;Chen Liang;Lv Yangge;Meng Guoliang;Hu Mei;Long Yan;Hong Hao;Tang Susu
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