弱电相互作用下钾离子跨膜输运机制的研究
11475053
2014
A2503.统计物理与复杂系统
展永
面上项目
教授
河北工业大学
90万元
弱相互作用;构象变化;钾离子通道;静电相互作用;膜磷脂
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 一种TMEM16A钙激活氯离子通道抑制剂的筛选方法 | 专利 | 展永;陈娅斐;郭鹏;安海龙;耿金鹏;王晖;袁宏博;赵小明;杜昱光 |
| 2 | Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel | 期刊论文 | Ren Shuxi;Pang Chunli;Huang Yayue;Xing Chengfen;Zhan Yong;An Hailong;Zhan Y;An HL |
| 3 | Allosteric Mechanism of Calmodulin Revealed by Targeted Molecular Dynamics Simulation | 期刊论文 | Liang Qian-Yun;Pang Chun-Li;Li Jun-Wei;Zhang Su-Hua;Liu Hui;Zhan Yong;An Hai-Long |
| 4 | Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions | 期刊论文 | Guan Ronghua;Zhou Hui;Li Junwei;Pang Chunli;Chen Yafei;Zhan Yong;An Hailong;Xiao Shaoying;Du Xiangrong;Ke Shaoxi;Tang Qiongyao;Su Jiguo;Zhan Y;An HL |
| 5 | Eag1 Voltage-Dependent Potassium Channels: Structure, Electrophysiological Characteristics, and Function in Cancer | 期刊论文 | Wang Xuzhao;Chen Yafei;Zhang Yuhong;Guo Shuai;Mo Li;An Hailong;Zhan Yong |
| 6 | Identification of Three Interactions to Determine the Conformation Change and to Maintain the Function of Kir2.1 Channel Protein | 期刊论文 | Li Jun-Wei;Xie Xiao-Xiao;Yu Hui;Zhan Yong;An Hai-Long;Xiao Shao-Ying;Zhang Hai-Lin |
| 7 | The Structural Stability of Alpha-Helix Determined by the Preference of Amino Acids | 期刊论文 | Xie Xiaoxiao;Li Junwei;Xiao Shaoying;Liu Yuzhi;Liu Hui;Geng Jinpeng;Zhang suhua;Yu Hui;Zhan Yong;An Hailong |
| 8 | 一种细胞膜电流抑制剂及其在抑制Kir2.1内向电流方面的应用 | 专利 | 展永;任树喜;安海龙;陈娅斐;张素花 |
| 9 | Identification of the Conformational transition pathway in PIP2 Opening Kir Channels | 期刊论文 | Li Junwei;Lu Shouqin;Liu Yuzhi;Pang Chunli;Chen Yafei;Zhang Suhua;Yu Hui;Long Mian;Zhang Hailin;Logothetis Diomedes E.;Zhan Yong;An Hailong |
| 10 | 用作TMEM16A离子通道激活剂的含人参皂苷Rb1的药物组合物 | 专利 | 展永;郭帅;陈娅斐;安海龙;王徐朝;柴燃;韩玥斌;祁金龙;张海林 |
| 11 | 一种TMEM16A钙激活氯离子通道激活剂的筛选方法 | 专利 | 展永;陈娅斐;郭鹏;安海龙;耿金鹏;王晖;袁宏博;赵小明;杜昱光 |
| 12 | 苏合香与细胞浴液混合物在抑制Kir2.1外向电流方面的应用 | 专利 | 展永;任树喜;安海龙;柳辉;李军委;韩玥斌 |
| 13 | Three pairs of weak interactions precisely regulate the G-loop gate of Kir2.1 channel | 期刊论文 | Li Junwei;Xiao Shaoying;Xie Xiaoxiao;Zhou Hui;Pang Chunli;Li Shanshan;Zhang Hailin;Logothetis Diomedes E.;Zhan Yong;An Hailong |
| 14 | Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A | 期刊论文 | Chai Ran;Chen Yafei;Yuan Hongbo;Wang Xuzhao;Guo Shuai;Qi Jinlong;Zhang Hailin;Zhan Yong;An Hailong |
| 15 | Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions | 期刊论文 | Guan Ronghua;Zhou Hui;Li Junwei;Pang Chunli;Chen Yafei;Zhan Yong;An Hailong;Xiao Shaoying;Du Xiangrong;Ke Shaoxi;Tang Qiongyao;Su Jiguo;Zhan Y;An HL |
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